Allergy & Immunology News Archive
Investigators examined whether excessive food allergy testing in patients with atopic dermatitis might lead to food intolerance when certain foods are removed from the diet.
Omalizumab rescue therapy produced rapid results in a patient with refractory status asthmaticus.
Providers believe stressing fetal protection is most effective strategy against refusal.
The study utilized the Vaccine Safety Datalink and included children who received the first dose of a measles-containing vaccine between 12 and 23 months old during the study period of January 1, 2003 to September 20, 2015.
Pediatric patients with peanut allergy may benefit from an oral immunomodulatory treatment that can reduce the severity of symptoms associated with peanut protein ingestion.
Significant reduction in attack rate compared with placebo seen for 3 dose regimens of lanadelumab.
Among children with food allergy, 53% of infants have milk allergy vs 15% of teens.
However, adjuvant recombinant subunit vaccine tied to more injection site adverse events.
Influenza Vaccines May Protect Against Lab-Confirmed Influenza-Linked Hospitalization During Pregnancy
For women who are pregnant, influenza vaccines may moderately protect against laboratory-confirmed influenza-associated hospitalization.
The prevalence of atopic dermatitis is 7.3% among US adults, and patients with atopic dermatitis and more severe disease have worse quality of life.
A second dose of Tdap, a reduced-antigen-content tetanus-diphtheria-acellular pertussis vaccine, 9 years after initial vaccination was well tolerated and immunogenic.
Vital wheat gluten oral immunotherapy induces desensitization in about half of patients with wheat allergy after a year of treatment.
Prior-season vaccination is not associated with reduced vaccine effectiveness among children aged 2 to 17 years.
Health officers and immunization staff reported concerns including an increase in medical exemptions.
Research results indicated vaccination rates declined as clinic day progressed and that active choice intervention was linked with increased vaccinations.
Viaskin Peanut, an epicutaneous immunotherapy (EPIT), delivers small amounts of peanut protein through a wearable patch to induce desensitization.
While primary care physicians overwhelmingly recommend pneumococcal vaccines, there is a gap in their knowledge of how to implement related vaccine recommendations.
In-hospital postnatal education about infant pain management at vaccinations leads to more frequent use of pain relief interventions
Third Trimester Immunization With Tdap Vaccine Optimal for Pertussis Toxin Antibody Concentrations in Newborns
Immunization with Tdap vaccine during the third trimester of pregnancy resulted in higher concentrations of pertussis toxin antibodies in newborns.
The burden of childhood and infant pneumonia can be effectively reduced through the use of the pneumococcal Haemophilus influenzae protein D conjugate vaccine.
The approval of the expanded age range was based on data from a clinical trial which evaluated the efficacy of Gardasil (quadrivalent human papillomavirus recombinant vaccine) in 3253 women 27-45 years of age with a median duration of follow-up of 3.5 years post-dose 3.
14 million need to receive two doses of vaccine to reach goal of 80% vaccination by 2026.
Wide variations in influenza vaccine coverage have been noted across healthcare personnel based on occupation and worksite.
Active Choice Intervention Effective in Increasing Influenza Vaccination Rates at Primary Care Practices
Influenza vaccination rates decline as the clinic day progresses.
Changes in allergy records were suggested by the allergy service consult for 62% of the patients.
Both doses will be supplied in single-dose, prefilled syringes for manual injection.
A documented β -lactam allergy was found in more than one-third of patients receiving broad-spectrum antibiotics, however, only 10% of patients were found to be truly allergic.
Monovalent Acellular Pertussis Vaccine Safe and Effective for Neonates With Mothers Unvaccinated for Tdap
The monovalent acellular pertussis vaccine may be beneficial to neonates whose mothers did not receive Tdap vaccine during pregnancy.
From 2008 to 2015, both cervical intraepithelial neoplasia grades 2, 3 and adenocarcinoma in situ rates and cervical cancer screening declined in women age 18 to 24 years.
Cockroach and mouse allergies were most often associated with poorly controlled asthma and exacerbations in urban adolescents.
Children of East Asian-born parents had an increased risk for allergic rhinitis and aeroallergen sensitization compared with children of Caucasian ancestry.
High population immunity is an indicator of the decline in serotype 2 Sabin vaccine poliovirus after serotype 2 oral poliovirus vaccine withdrawal.
Children born by cesarean delivery who were large for gestational age and had low Apgar scores may be at increased risk of developing a food allergy.
Although allergic sensitization and hay fever rates increased as children grew older, the rates of asthma dropped.
As infections from drug-resistant microbes continue to rise, the development of new antibiotics has declined since the golden age of antibiotic discovery in the mid-20th century.
This effort is in response to epinephrine auto-injector supply issues reported by manufacturers to the Food and Drug Administration (FDA).
According to the report, the patient complained of a non-productive cough, accumulation of mucus, and post-nasal drip and requested a thorough assessment of her medical conditions.
No association was observed between prenatal vaccination of Tdap vaccination and an increased risk of autism spectrum disorder risk in children.
All children age 6 months and older, including teens, advised to undergo annual immunization.
Overall response of platelet count 50,000/L seen in 43% of patients.
Specimens of the rapidly evolving virus are needed to develop vaccines and treatments.
Due to a gap in knowledge regarding serogroup B meningococcal (MenB) disease and vaccination, the majority of clinicians are not discussing MenB vaccines with their adolescent patients during routine visits.
In general, routine annual vaccination is recommended for all patients ≥6 months of age who have no contraindications.
A malaria transmission-blocking vaccine, Pfs25H-EPA in Alhydrogel®, was well tolerated and safe and induced significant blockage of parasite transmission, but this activity was only seen at peak titers after 4 vaccine doses.
What's the best way to tell your anti-vaccine patients the truth about vaccines?
Researchers sought to identify parental predictors of HIV vaccination in low-income adolescent Hispanic girls.
Unlike other generic approvals, epinephrine auto-injectors are considered "combination products" because they consist of both a drug and a device, making the approval process more challenging.
Immunization with Tdap vaccine during pregnancy results in higher levels of antibodies early in infancy but lower levels after the primary vaccine series.
First to be vaccinated will be health workers, contacts of confirmed Ebola patients.
Children and young adults with asthma and multiple food allergies may be at risk for reduced small airway lung function than children with a single food allergy.
Research shows that patients diagnosed with atopic dermatitis experience feelings of dissatisfaction with regard to lifestyle, as well as impaired health and wellness.
Sensitization to Aspergillus fumigatus increased the risk for severe asthma.
Oral administration of BCX7353 at dose of 125 mg results in lower rate of attacks vs placebo.
For adolescents and young adults, the co-administration of quadrivalent meningococcal conjugate vaccine with incorporated tetanus toxoid with diphtheria-tetanus-acellular pertussis vaccine is noninferior to isolated vaccination and does not compromise immunity.
Grass, other weeds, and unclassified pollen were significantly associated with increased risk for asthma hospitalization in young children.
A significant decline in rotavirus disease-associated hospitalization, emergency department visits, and physician office visits was demonstrated in children younger than 5 years following implementation of the rotavirus vaccine.
Women receiving the inactivated influenza vaccine demonstrated superior antibody response compared with those receiving the live attenuated influenza vaccine.
Less than a year following the initial direct-to-tumor vaccine injection, all treated tumors disappeared.
Vaccinated women and girls living with HIV may be at greater risk for HPV vaccine failure compared with women and girls without HIV.
Exemption from vaccination is common in Arizona school districts due to lack of trust in medical establishments.
Respiratory symptoms were more common in older children compared with infants who presented with food-induced anaphylaxis.
Inverse association identified between NME rate and MMR vaccine coverage of kindergarteners.
The administration of PCV7 and PCV13 reduced the number of ambulatory visits for otitis media in pediatric patients.
Lone star tick is most common in the South, but may be spreading to new areas
Using state- and individual-level data from the 1995-2014 National Immunization Survey, the effect of a state's Universal Purchase adoption on vaccination rates was estimated.
Others have argued that dismissal is ethically problematic because it can deprive children of comprehensive pediatric care and undermine public health.
Adherence and completion to multidose vaccine schedules for hepatitis A, B, and A-B are low, thereby rendering vaccination ineffective.
From 2007 to 2015, the majority of initial hepatitis A, B, and A/B vaccinations were administered by primary care providers.
The 2017-2018 influenza season in the United States (October 1, 2017-May 19, 2018) was a high-severity season.
Systemic shift in glucose metabolism from oxidative phosphorylation to aerobic glycolysis.
The risk of intussusception within 1 to 7 days and 8 to 21 days after rotavirus vaccination was assessed in infants age 28 to 245 days.
Researchers developed a predictive algorithm to identify individuals with a higher risk for severe reactions to the standardized peanut oral food challenge.
Early vaccination of autologous hemopoietic stem-cell transplant (auto-HSCT) recipients during the peri-transplant period can be effective for the prevention of infections such as herpes zoster.
Significant, positive link for common allergies, especially food allergy, with autism
In a phase 3 clinical trial, early vaccination effectively prevented herpes zoster in auto-HSCT recipients.
Between October 20, 2017 and February 20, 2018, the Vaccine Adverse Event Reporting System (VAERS) received 155 reports involving RZV, with 13 (8%) involving an administrative error.
The hexavalent DTPa-HBV-IPV/Hib vaccine may not affect Hib vaccine efficacy.
The CDC recommends 2 doses of the MMR vaccine, which provides 97% protection against measles, prior to international travel.
Humoral response seen for 97.8% of HZ/su vaccine recipients vs 2% of placebo
High-certainty evidence for protection in adolescent girls and young women aged 15 to 26 years
The US Food & Drug Administration (FDA) has released updated tips for the treatment of seasonal allergies.
The researchers enrolled 25 platinum-pretreated, immunotherapy-naïve patients with recurrent advanced epithelial ovarian cancer (EOC) for the trial.
This updated Committee Opinion includes more recent data on the safety and efficacy of influenza vaccination during pregnancy, as well as recommendations for treatment and postexposure chemoprophylaxis.
Intake may lead to aggravation of symptoms in patients with atopic dermatitis, birch pollen allergy
Some allergic diseases associated with acid-suppressive, antibiotic intake in infants younger than 6 months old include food allergies, anaphylaxis, asthma, and allergic rhinitis.
Maternal diet may be correlated with certain autoimmune-associated diseases in offspring.
TDF did not reduce mother-to-child HBV transmission in mothers taking hepatitis B Ig and HBV vaccine.
Clinicians using communication training and fact sheets to inform adolescents about HPV, significantly increased vaccination initiation and completion rates among their patients.
Increasing awareness of and access to newer HIV testing options such as free or reduced price on home and self-tests and couples HIV testing and counseling can facilitate increased levels of consistent testing among young, Black MSM, and transgender women.
Researchers sought to assess the effect of seasonal dose adjustments on the rate of systemic reactions in pediatric patients receiving standardized allergen subcutaneous immunotherapy.
Researchers assessed the use of dupilumab in adults with chronic rhinosinusitis and nasal polyps who did not respond to treatment with intranasal corticosteroids.
The 2017 to 2018 influenza vaccine reduces the chance of getting the disease by about 33%, but is only 25% effective against H3N2, otherwise known as influenza A.
The Advisory Committee on Immunization Practices updated its immunization recommendations for adults.
The updates contain new or revised ACIP recommendations for poliovirus, influenza, and measles, mumps, and rubella vaccines, as well as a clarification of the recommendations for rotavirus and pneumococcal vaccines.
Herpes zoster subunit vaccine more effective, less expensive than live attenuated herpes zoster vaccine
The adjuvanted herpes zoster subunit vaccine is more effective and less expensive than the live attenuated herpes zoster vaccine at all ages.
Younger adults are more likely to have provider-ordered flu testing than older adults.
Intensive care and death were greatly prevented in patients who were annually vaccinated.
Inactivated and live attenuated flu vaccines can be safely administered to people with egg allergies.
Day-care centers have more allergens from pets and mites than in homes.
A Minnesota-based hospital chain fires about 50 employees for refusal to receive the influenza vaccine.