As infection may also lead to worsening symptoms in patients with myasthenia gravis, clinicians must balance prompt and adequate treatment of infection with the risk that some antibiotics can aggravate the condition.
Treatment with oral clindamycin for pregnant women with bacterial vaginosis in their first trimester does not reduce the risk of late miscarriage or very preterm delivery.
Clinicians who prescribe gabapentin for off-label uses should assess available evidence for a given indication.
The clinical profiles of patients taking over-the-counter pain medications were found to be poorer than expected, with a high prevalence of migraine headache and many reporting frequent and disabling pain for extended durations.
Prescription of antibiotics and acid-suppressing medications in early childhood is associated with an increased risk for obesity.
Probiotics provided to reduce the risk for common acute infections may be associated with reduced antibiotic use in infants and children.
Among patients undergoing total knee arthroplasty, aspirin alone may provide protection against postoperative venous thromboembolism that is similar to that of other anticoagulants.
The inappropriate use of antibiotics as prophylaxis and treatment in acute pancreatitis is common, highlighting the efforts required for antibiotic stewardship.
The rates of Group B Streptococcal bacteremia recurrence in infants with an initial course of late-onset infection who received shortened and prolonged IV antibiotic therapy were 1.8% and 2.3%, respectively.
New data suggest an association between general practitioners' prescribing habits for urinary tract infections and UTI-related E coli bacteremia incidence.
For certain patients with endocarditis on the left side of the heart under stable condition, switching from intravenous (IV) antibiotics to orally administered antibiotics is noninferior to staying on IV treatment.
This research rejects any association between increased risk for ADHD and changes in children's microbiota related to cesarean delivery or antibiotic use.
As infections from drug-resistant microbes continue to rise, the development of new antibiotics has declined since the golden age of antibiotic discovery in the mid-20th century.
Findings support ED discharge with oral antibiotics for children with urinary tract infection.
However, completing individual bundle elements in that timeframe does not reduce pediatric mortality.
A systematic literature review, published in Clinical Infectious Diseases, found no evidence supporting a benefit to antibacterial therapy for osteomyelitis in patients with stage IV sacral pressure ulcers.
Antibiotic prophylaxis should be reconsidered with bicuspid aortic valve, mitral valve prolapse.
ACX-362E is a targeted, narrow spectrum oral antibiotic that blocks the DNA replication process through inhibition of polymerase III, which has been shown to be bactericidal.
Antibiotic resistance is a nationwide issue that affects every state, so how do we combat it?
Aortic aneurysm risks are significantly elevated in patients taking fluoroquinolone.
Treating lower UTIs with diclofenac may help in optimizing antibiotic treatments.
Completing the antibiotic course increases the chance of patients developing antibiotic resistance, according to the authors.
Antibiotics do not always need to be used for cutaneous abscesses, but the condition must be evaluated on a case-by-case basis to make a final decision regarding the appropriate course of treatment for any individual.
General practices that prescribe fewer antibiotics may encounter slightly higher incidences of pneumonia and peritonsillar abscess.
Regarding antibiotic use for upper respiratory infections, patients and providers have different perceptions, behaviors, and knowledge.
Research findings support the need to establish a goal of increased antibiotic stewardship among physicians.
Nearly 54% of pediatric UTI cases were resistant to treatment with amoxicillin.
Acute sinusitis is common, affecting 6% to 7% of children presenting with respiratory symptoms.
In outpatient primary care settings, various behavioral interventions can reduce the rate of inappropriate antibiotic prescribing practices.
CDC, ACP issue guidelines for appropriate antibiotic use for acute respiratory tract infection in adultsJanuary 20, 2016
Reducing inappropriate antibiotic prescribing will improve the quality of patient care, decrease healthcare costs, and preserve the effectiveness of antibiotics.