Asthma Information Center Archive

CD63 Ratio May Predict Allergic Reaction Severity in Peanut Food Challenge

Researchers developed a predictive algorithm to identify individuals with a higher risk for severe reactions to the standardized peanut oral food challenge.

Respiratory Pathogens May Increase Treatment Failure Risk in Asthma

Increased risk of treatment failure for children with asthma exacerbations presenting to the ER.

Prevalence of Obese, Allergic Asthma Phenotypes Examined in US Children

The study authors examined data obtained from the 2007-2008 National Survey of Children's Health (NSCH) to determine the prevalence, risk factors, as well as the severity of asthma phenotypes.

Low Neighborhood Walkability Increases Risk of Asthma in Kids

Findings among children for both incident asthma and ongoing asthma.

Early Child Care Attendance and Asthma, Wheeze Risk: Is There a Link?

Early child care attendance increased the risk for wheeze in children ≤2 years of age but decreased the risk for asthma in children 3 to 5 years of age.

Pediatric Asthma Unaffected by 5-fold Increased Inhaled Glucocorticoid Dose

Increasing inhaled glucocorticoid doses at initial signs of exacerbating asthma may not be effective.

Assessing LABA, LAMA treatments for persistent asthma control

Single maintenance and reliever therapy and long-acting muscarinic antagonists are linked to better management of asthma in patients with uncontrolled, persistent asthma.

Asthma, allergic rhinitis prevalence with long-term opioid use

Patients with opioid dependence or abuse may exhibit a higher prevalence of asthma compared with the general population.

Prenatal vitamin D may increase pediatric allergic rhinitis risk

Prenatal vitamin D is associated with an increased risk for allergic rhinitis in children born to African American women, but not white women.

Inhaler use in asthma and COPD: Patient characteristics compared

Researchers examined real-world characteristics of patients receiving albuterol multidose dry powder inhaler or short-acting β2 agonists with short-acting β2 agonists for asthma and chronic obstructive pulmonary disease.

Dupilumab treatment in moderate to severe atopic dermatitis

Researchers assessed whether the administration of dupilumab improves signs and symptoms of atopic dermatitis in patients with or without comorbid asthma.

Sex-based young adult asthma risks associated with acetaminophen use

Data from the Isle of Wight birth cohort study and the Kuwait University Allergy cross-sectional study were used to assess self-reported acetaminophen use and asthma diagnosis.

Race-dependent protective effect of maternal vitamin D on childhood asthma

A cohort from the CANDLE study was assessed to determine if race plays a role in the protective effect of maternal vitamin D levels on childhood asthma.

Obesity in preschoolers leads to exacerbated asthma

Overweight/obese preschools have greater asthma symptoms than normal-weight children when untreated.

FDA removes Boxed Warning from select asthma, COPD medications

New evidence regarding safety is spurring the US FDA to remove a Boxed Warning from certain inhaled medications used to treat asthma and COPD.

Half of adults with work-related asthma receive pneumococcal vaccination

The researchers found that 42% of the estimated 12 million ever-employed adults with current asthma had received a pneumococcal vaccine.

Asthma associated with later development of inflammatory bowel disease

Asthma was associated with Crohn's disease and with early- and late-onset ulcerative colitis.

Oral corticosteroids not effective for lower respiratory tract infection

No significant effects were found from oral corticosteroid use for acute lower respiratory tract infection in adults without asthma.

Eosinophilic COPD vs COPD with asthma: comparing clinical characteristics

Distinct differences occur between eosinophilic COPD and COPD patients with asthma.

Asthma attacks can be triggered by thunderstorms

A 2016 thunderstorm asthma outbreak in Australia occurred when high grass pollen concentrations were dispersed by strong winds.

Low vitamin E in pregnant women increases asthma risk in offspring

Research presented at the AAAAI Annual Meeting suggests a link between maternal vitamin E levels and childhood asthma development.

Inhaled corticosteroids not tied to pneumonia in children with asthma

Results showed no link between inhaled corticosteroids and risk of pharyngitis, otitis media, or sinusitis.

One-third of asthma patients may be misdiagnosed

About one-third of adults with physician-diagnosed asthma in the last 5 years may not have a current diagnosis.

Monitoring asthma control in children: AAP recommendations for clinicians

Recent advances in measuring asthma control tools have enhanced ongoing assessment and monitoring of asthma.

Prenatal fish oil supplementation may reduce asthma risk in children

Supplementation during pregnancy was associated with reduction in risk of persistent wheezing and asthma in offspring.

Higher cured meat intake linked to worsening asthma

Cured meat intake levels also had an indirect effect mediated by body mass index.

Exposure to mold and dampness may increase risk of asthma and rhinitis

Exposure during infancy was associated with increased risk up to 16 years of age, especially for nonallergic disease.

Indoor environmental control strategies to manage asthma in children

Strategies include source removal, source control, and asthma education.

Omalizumab effective for asthma and overlapping COPD

Omalizumab is useful in the management of severe asthma with overlapping COPD.

Children with farm exposure have decreased regulatory T cells

Regulatory T cells are decreased with farm exposure and increased among those with asthma.

Endoscopic sinus surgery may improve asthma quality of life in rhinosinusitis

Endoscopic sinus surgery improved asthma quality of life and control in patients with uncontrolled asthma.

Allergic sensitization is common in pediatric asthma

Children were assessed for allergic sensitization by two microarray system. As a result, 47% of children had allergic sensitization.

Food allergies in children linked to high risk of asthma, rhinitis

Researchers measured rates of childhood allergic conditions with data from healthcare provider-based diagnoses.

Rates of asthma, ADHD increasing among children living in poverty

Rates of chronic conditions are on the rise in children, and children living in poverty have a higher risk of ADHD and asthma, compared with wealthier children.

Pediatric asthma is regularly overdiagnosed

Inhalers are often inappropriately prescribed to children assumed to have asthma without proper diagnostic testing.

Asthma prevalence higher in obese adults

A National Center for Health Statistics study found significantly higher rates of asthma prevalence among obese women compared with men.

People with asthma more likely to develop chronic migraine

In a study of 4,446 Americans, more than 5% of people with asthma developed chronic migraine, compared to 2.5% of those without.

Stepping down asthma meds 
can be safe

Patients with well-controlled asthma may safely reduce their current level of medication, according to a study published in the Journal of Allergy and Clinical Immunology.

Vitamin D does not reduce cold severity, frequency in adults with asthma

The use of vitamin D supplements does not reduce the severity or frequency of colds in adults with mild-to-moderate asthma.

Children with asthma fare better with specialized treatment from allergists

Research presented at the ACAAI Annual Scientific Meeting shows that asthmatic children treated by allergists fare better than those treated by general practitioners.

LABAs, tiotropium perform similarly in black patients with asthma

The addition of tiotropium or LABAs results in similar outcomes for black patients with asthma being treated with inhaled corticosteroids.

Asthma treatment less likely to work as patients age

Patients aged 30 years are older are more likely to experience unsuccessful asthma treatment.

Asthma risk increased by prenatal exposure to H2Bs, PPIs

Pregnant women who use H2 blockers or PPIs increase their offspring's risk for asthma.

Asthma treatment failure more likely in older adults

Having respiratory condition for longer time, lower lung function may be factors

Aerobic exercise may help reduce asthma severity

Improved airway function in those who had more vigorous workouts

Magnesium helps prevent, manage asthma attacks

Daily oral supplements and a magnesium-rich diet is efficient in managing mild, moderate and severe asthma exacerbation.

Asthma clinic improves triage from emergency department to primary care

An express clinic implemented in the ED can help bridge the gap to primary care after acute asthma exacerbations.

Peanut allergy underdiagnosed in kids with asthma

Similarities in symptom presentation makes it easy to miss peanut allergies in children with asthma.

Soy provides no benefits for asthma care

Clinical trial refutes prior notion that the nutrient might boost lung function

Patient education essential for improving asthma control

Consider designating dedicated clinic personal to educate patients about proper inhaler use.

High albuterol inhaler costs linked to chlorofluorocarbon ban

An FDA ban on chlorofluorocarbon increased the cost of albuterol inhalers, which before the ban, contained chlorofluorocarbon.

VNN1 gene may be potential biomarker for childhood asthma

The activity of a gene called vanin-1 (VNN1) affected whether they were good or poor responders to corticosteroid treatment.

Bariatric surgery cuts asthma-related hospital visits

Significantly fewer ED visits or hospitalizations for asthma exacerbation occurred within 12 months after bariatric surgery.

Intervention cuts inappropriate PPI prescriptions

Increase in proportion of PPIs discontinued at hospital discharge after intervention implementation.

Parents' depression ups asthma risk for baby

And older antidepressants in pregnancy showed similarly increased odds.

Work-related asthma goes unaddressed in many adult patients

Only 14.6% of patients surveyed who discussed their asthma and work with a health-care professional.

Demographics, not location, explain high inner-city asthma rates

Associations with asthma morbidity were very similar to those with prevalent asthma.

Acetaminophen use during pregnancy: is it safe?

A meta-analysis reveals a weak association between acetaminophen use during pregnancy and the development of childhood asthma.

Asthma, COPD linked with more inflammatory bowel disease

People with airway diseases are more likely to have inflammatory bowel disease.

Many colleges lack resources to care for students with chronic health conditions

Only 24% of college medical directors reported contacting students to make a first-time appointment.

Overweight, obese kids with asthma overuse rescue meds

Overweight/obese children reported more frequent rescue treatments despite lower fraction of exhaled nitric oxide and reduced methacholine responsiveness.

Poverty linked to increased respiratory-related hospitalizations

Low income patients had nearly three times the odds of hospitalization compared with high income patients.

Asthma mortality rate highest in older women

Risk for osteoporosis, glaucoma, cataracts, and adrenal suppression elevated among women with asthma aged 65 years and older.

Obesity, gestational weight gain associated with child asthma risk

Each 1-kg/m2 increase in maternal BMI was associated with a 2% to 3% increase in the odds of childhood asthma.

Antibiotics in infancy may increase asthma risk

Patients treated with antibiotics in the first 12 months of life had more asthma exacerbations and related hospitalizations later in life.

FDA reviews OTC Singulair use

Inappropriate use in children under 15 years old and patients seeking relief for asthma cited as top concerns.

ALA: Almost half of all Americans breathe unhealthy air

High-risk patients include those with pulmonary diseases, heart diseases and diabetes.

Asthma drug treats food allergy

Omalizumab (Xolair) may help people minimize food allergies.

Pediatric asthma cases peak in September

Increase in asthma exacerbations, asthma meds prescriptions and asthma-related primary care visits.

Proper asthma inhaler technique lacking in urban minorities

Very few caregivers of urban minority children with persistent asthma are familiar with the the correct steps for using a metered-dose inhaler.

Novel drug effective for asthma, COPD

Drug is an effective bronchodilator, bronchoprotector, and anti-inflammatory

One in five children outgrow asthma

About one fifth of children with asthma will experience remission; however, this outcome is less likely for girls and those with animal allergies.

Sucking on pacifier may reduce child's allergy risk

Parents who suck on their child's pacifier to clean it may be decreasing their child's risk for developing eczema and asthma.

Pesticides, antibacterials linked to asthma Rxs

Patients with high levels of urinary phenols were more likely to be prescribed asthma medication than those with low concentrations.

Respiratory virus patterns differ in urban, suburban kids

Adenovirus is more prevalent among children living in inner-city areas, and may help explain higher asthma prevalence in urban populations.

Asthma treatment response reduced in obese patients

Higher levels of neutrophilic inflammation may explain why obese patients with asthma respond less to corticosteroid treatment.

Nurse-initiated steroids improve pediatric asthma care

Time to clinical improvement and discharge was shortened for children with asthma admitted to the pediatric emergency department.

Common products may contain endocrine-disrupting chemicals

A wide range of consumer products contain hormone-disrupting and asthma-related chemicals, results of a large peer-reviewed study indicate.

Obese children with asthma need higher corticosteroid doses

High BMI linked to decreased corticosteroid response among children with asthma.

Allergy-related diseases affect majority of children

More than 50% of children in a population-based cohort study developed eczema, asthma and rhinitis before the age of 12 years.

Heavy soda drinking linked to lung disease

Participants in an Australian study who drank at least a half a liter of sugar-sweetened beverages per day more than doubled their chances of developing asthma or chronic obstructive pulmonary disease.

Proton-pump inhibitors overused for non-GERD pediatric asthma

Treatment with lansoprazole did not improve asthma control in children without overt gastroesophageal reflux disease (GERD), and was associated with adverse events including increased risk for respiratory infection, sore throat and bronchitis.

Prescription replacements necessary for OTC asthma inhalers

Patients with asthma will not be able to purchase over-the-counter epinephrine inhalers after Dec. 31, 2011.

Power of placebo evident in asthma treatment

Clinicians should interpret patient self-reports with caution, and clinical trials should rely more heavily on objective outcomes when determining optimal asthma care.

Sunlight can help kids avoid asthma

Summertime may become even more youth-friendly with the recent discovery that the vitamin D produced from sun exposure plays a role in protecting against childhood asthma.

Asthma benefit of GERD drugs too small

Magnitude of proton pump inhibitor therapy unlikely to be of meaningful clinical significance.

Early pet exposure reduces later allergy development

People exposed to pets during their first year of life were less likely to develop allergies in adolescence and adulthood.

One-third of kids with asthma forgo flu vaccine

Many parents of kids with asthma are not having their children vaccinated against influenza due to unfounded fears about the vaccine's adverse events.

Antibiotics overused in children with asthma

Nearly one-in-six children who visit a pediatric ambulatory care center for asthma are prescribed an unnecessary antibiotic.

Anti-leukotrienes equivalent to standard asthma care

Leukotriene-receptor antagonists were just as effective as inhaled glucocorticoids as first-line controller and add-on asthma therapy, study finds.

Immunosupression in kids with asthma

A short course of oral corticosteroids in children with acute asthma may temporarily depress immune response to a new antigen, but this situation resolves within six weeks and has no apparent impact on response to known antigens.

Health outcomes of Gulf oil spill still uncertain

Public health officials criticize the National Institute of Environmental Health Sciences study, currently underway to measure the impact of the disaster, for late start and faulty design.

Omalizumab improves asthma control in inner-city children

Anti-IgE antibody significantly reduced seasonal peaks in asthma exacerbations and the need for medication.

Only OTC asthma inhaler to be withdrawn from market

Primatene Mist will be discontinued next year as part of international environmental initiative.

School-based intervention improved asthma symptoms

A simple intervention implemented by school nurses may serve as a model for improving asthma care in urban communities.

Combination therapy effective for asthma rescue

Administering beclamethasone with albuterol better than albuterol alone.

Asthma drug not safe for obstetric use

Terbutaline can cause maternal heart problems and death, FDA warns.

Slightly elevated bilirubin may protect against lung cancer, COPD

Higher bilirubin levels among people with levels in the normal range reduced the risk of lung cancer, death and chronic obstructive pulmonary disease.

Vitamin D deficiency may hasten autoimmune lung disease

Vitamin D supplements may be a cheap, natural treatment for patients with autoimmune lung diseases.

Provider interest helps asthma compliance

Keep a close watch over medication use and review detailed electronic prescription information.

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