Apixaban in Patients With ESRD and Atrial Fibrillation
There are limited published data on the efficacy and safety of direct-acting oral anticoagulants (DOACs) in patients with end-stage renal disease (ESRD) on dialysis and atrial fibrillation.
There are limited published data on the efficacy and safety of direct-acting oral anticoagulants (DOACs) in patients with end-stage renal disease (ESRD) on dialysis and atrial fibrillation.
Questions about the generalizability of previous data on dual antiplatelet therapy after minor ischemic stroke or high-risk transient ischemic attack lead investigators of the POINT trial to conduct a similar study in an international population.
Albiglutide is available in other countries, and this trial may serve as an impetus for its reintroduction in the United States, particularly if follow-up results show a survival advantage with albiglutide.
Starting with physical therapy and having surgery only if that failed was as effective as immediate surgery in patients with osteoarthritis of the knee.
Although the American Academy of Dermatology recommends the direct application of emollients to the skin in patients with atopic dermatitis, the addition of oils, emollients, or other additives to bath water is not recommended due to insufficient evidence regarding their efficacy.
Although endocrine therapy following surgery is recommended for HR-positive/HER2-negative, axillary node-negative breast cancers, the value of adjuvant chemotherapy in the setting of moderate risk is unclear.
Although exclusive breastfeeding for the first 6 months of life is recommended by several health organizations, there may be a delay before abundant maternal milk production is established.
The SYGMA trials assessed the use of an as-needed combined corticosteroid/beta-agonist inhaler in patients with mild asthma.
The decreased rate of respiratory complications with betamethasone suggests antenatal steroids may improve the respiratory status in late preterm infants.
Regular proton pump inhibitor use in the elderly was associated with an increased risk of incident dementia compared with no proton pump inhibitor use, according to researchers.