Joslyn Kirby, Author at Clinical Advisor

Joslyn Kirby

All articles by Joslyn Kirby

Lymphomatoid Granulomatosis

Are You Confident of the Diagnosis? What to be alert for in the history Lymphomatoid granulomatosis (LYG) should be considered when a patient presents with multiple papules, plaques or nodules, constitutional symptoms (fever, fatigue, night sweats, weight loss) and pulmonary symptoms (dyspnea, sinusitis, cough). LYG is a multisystem lymphoproliferative disease due to B-lymphocytes latently infected…

Leukemia Cutis (Leukemia specific skin lesions, myelosarcoma, granulocytic sarcoma, monoblastic sarcoma, chloroma, primary extramedullary leukemia, aleukemic leukemia cutis)

Are You Confident of the Diagnosis? The term leukemia cutis (LC) describes the skin changes caused by infiltration of extramedullary leukemic cells. Leukemia can be myeloid or lymphoid and acute or chronic. Acute leukemias are due to malignant transformation of leukocytes early in development while chronic leukemias arise from more differentiated malignant leukocytes. Most pateints…

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