Maria Miklowski

I. What every physician needs to know. Background Henoch Schönlein Purpura (HSP) is the most common small vessel vasculitis seen in children. Though it affects children predominately, 10-28% of patients with HSP are adults. The disease has also been called Schönlein-Henoch purpura, anaphylactoid purpura and purpura rheumatica. The 2012 International Chapel Hill Consensus Conference on…

Goodpasture’s disease (anti-GBM disease) I. What every physician needs to know. Anti-glomerular basement membrane (anti-GBM) disease is a rare autoimmune disease in which anti-GBM antibodies are directed against the NC1 domain of the alpha -3 chain of type IV collagen of glomerular and alveolar basement membranes and clinically may result in rapidly progressing glomerulonephritis and…