In patients with COPD and hypercapnia, the use of home noninvasive positive pressure ventilation compared with no device was significantly associated with improved clinical outcomes but no significant differences in quality of life.
Investigators sought to identify neurobiological and psychological predictors for risk for psychosis.
Researchers suggest that childhood trauma exposure exerts illness-specific effects on hippocampal structures in patients who are women with first-episode schizophrenia.
From a small cohort in China, researchers found data that showed in patients with early-stage schizophrenia, peripheral multisystemic and central nervous system abnormalities may interact through the choroid plexus.
In a small Chinese cohort, investigators found that insular functional dysconnectivity within the sensory cortex may be a system-level neural substrate that precedes the onset of psychosis.
Future advancements in delivery technologies of antipsychotics and their evaluation in clinical trials could help increase the number of available antipsychotic formulations for the treatment of psychiatric disorders, including transdermal antipsychotic drug formulations for patients with schizophrenia.
Real-world data suggest that, before determining that a patient has clozapine-resistant schizophrenia, combination antipsychotic therapy should be sought.
In Brazil, researchers assessed blood serum identified with the use of proton nuclear magnetic resonance spectroscopy in an effort to differentiate individuals with psychiatric disorders, including schizophrenia and bipolar disorder.
Sleep abnormalities are common in schizophrenia, often even before psychosis onset, but the mechanisms behind this are unclear; therefore, researchers analyzed a possible link between genetic risk for schizophrenia and sleep phenotypes.
In The Netherlands, researchers found that in patients with schizophrenia, coping skills are a determinant in recovery.
