For patients with chronic sciatica, gabapentin is superior to pregabalin, with fewer and less severe adverse events.
Integrating graded in vivo exposure into the management of chronic lower back pain may result in improved treatment efficacy and reduced pain-related fear.
Spinal manipulative therapy plus exercise more effective than exercise alone over 1-year period.
Differences exist in race and gender in patients with chronic lower back pain, especially in pain sensitivity and severity due to aftersensations from mechanical punctuate pain and deep muscle hyperalgesia.
There is a lack of evidence supporting the benefits of combination drug therapy over monotherapy for the management of low back pain and sciatica.
Chronic low back pain (LBP) defined as persistent or fluctuating musculoskeletal pain of lower back and lumbar spine lasting >3 months.
The phase 3 SUMMIT-07 trial assessed the safety, efficacy, and tolerability of a new mu-opioid receptor agonist analgesic in adults with moderate to severe chronic lower back pain.
Adding corticosteroids to epidural lidocaine injections does not improve patient-reported pain or function at 12 months.
Improvements in low back pain intensity and disability among active-duty military personnel
The researchers found that patients who received the injection had significantly lower intensity of pain at six weeks and at three months compared with patients who didn't.
For patients with chronic low back pain, opioids may provide some short-term relief but are unlikely to be effective within recommended doses.
Mindfulness-based stress reduction and cognitive behavior therapy may be useful to improve chronic low back pain.
Standing for five or more hours at work leads to increased muscle fatigue.
Researchers have developed a way to determine back pain patients' risk for chronic pain.
Acetaminophen provided a small benefit in the reduction of pain and disability in patients with osteoarthritis of the hip or knee and provided no benefit in reducing pain in patients with lower back pain.
The risk of back pain was highest between 7 a.m. and noon.
Compared with the control group, the changes in pain intensity were higher in the bright light group.
Fluctuating nature of low back pain suggests measuring outcomes more frequently may aid prediction.
A woman suffers cyclic pain after multiple abdominal and pelvic surgeries.
Opioids may provide some short-term relief for low back pain, but evidence on long-term outcomes lacking.
One in five patient encounters do not include palpation.
Patients' perception that their pain will persist significantly predict worse short- and long-term outcomes for low back pain.
Epidural corticosteroid injections only offers short-term relief of leg pain and disability for patients with sciatica.
Review shows use of self-management techniques has minimal effect on pain and disability.
Symptom-guided therapy relieves back pain and improves outcomes for patients with severe sciatica.
Relaxation massage and structural massage each surpassed usual care in improving pain and function in patients with chronic low back pain.
Fulranumab no more efficacious than placebo for treating patients with chronic low back pain.
What are the side effects of fentanyl?
Mixed evidence supporting duloxetine for treatment of chronic low-back pain.
Nothing offered more than temporary relief for the aching, constant pain, which was unaccompanied by other symptoms.