Cardiovascular Information Center Archive

Peripheral Arterial Disease Diagnosis and Management Updates

A review of the 2016 American Heart Association and American College of Cardiology guidelines for management and diagnosis of peripheral arterial disease.

Artificial Intelligence Can Use Routine ECGs to Identify Heart Disease

Those with positive AI screen 4 times more likely to develop future ventricular dysfunction.

FDA-Approved Wearable Blood Pressure Monitor Now Available

HeartGuide is designed as a wrist watch that uses the oscillometric cuff method, the standard for medical-grade personal blood pressure measurement.

Exercise Can Consistently Lower Blood Pressure

Exercise can consistently yield reductions in blood pressure.

Hypertension With Psoriasis Tied to More Cardiac Interventions

In patients with hypertension, psoriasis linked to increased risk for cardiovascular procedures, surgeries.

In-Hospital Morbidity, Mortality Up With Flu in Heart Failure

Higher incidence seen for in-hospital mortality, acute respiratory failure, acute kidney injury.

Reducing Systolic Blood Pressure With Liraglutide: Predictors and Correlates

Patients with type 2 diabetes treated with liraglutide experience a greater reduction in systolic BP if they have lower baseline continuous glucose monitoring values and higher diastolic BP.

Moderate Drinking Not Harmful for Seniors With Heart Failure

Compared with abstinence from alcohol, increased survival seen with moderate drinking.

Do More Aggressive Periprocedural Antibiotic Regimens Reduce Risk of Device-Related Infections?

The clinical effectiveness of incremental periprocedural antibiotics for patients receiving cardiac implantable electronic devices was examined.

IVUS-Guided DES Implantation Improves Clinical Outcomes in Broad Range of Patients

IVUS-guided DES implantation resulted in a lower incidence of target-vessel failure at 12 months for patients undergoing PCI.

Exposure to Metals, Pesticides Tied to CVD in Hispanics/Latinos

Prevalence ratio for any cardiovascular disease was 2.18 for those working with pesticides.

Blunted Cardiovascular Stress Reactivity in Fibromyalgia With Comorbid PTSD

For women with fibromyalgia, comorbid posttraumatic stress disorder may contribute to blunted cardiovascular reactivity to stress.

Cognitive Decline Similar After Cardiac Surgery, Catheterization

No subjective memory decline observed in association with cardiac surgery in older adults.

ACC, AHA Publish Appropriate Use Criteria Guidelines for Peripheral Artery Intervention

In publishing updated appropriate use criteria, the organizations hope to provide guidance to clinicians who may refer patients for revascularization therapy.

Study Finds Cottonseed Oil Better Than Olive Oil at Improving Cholesterol Profiles, Triglyceride Levels

A diet rich in cottonseed oil was found to improve cholesterol and triglyceride levels in healthy men.

Medication Errors Resulting in Death Most Common in Elderly

Most common medication error category was omitted medicine or ingredient.

Pregnancy Losses Linked to Risk for Cardiovascular Disease

Women with 5 or more live births at increased risk for coronary heart disease, hospitalized MI.

Flu Vaccine Linked to Reduced Risk for Death in Heart Failure

After adjustment for confounders, vaccine linked to lower all-cause, cardiovascular death.

Western Culture, Not Age, Linked to Elevated Blood Pressure

Members of 2 remote Venezuelan tribes were found to have elevated blood pressure following exposure to Western culture.

Survival Similar With Donor Hearts From Hepatitis C+ Donors

Second study shows no significant difference in patients' survival based on donor BMI.

Childhood Behavioral Interventions May Promote Adult Cardiovascular Health

Focusing on children for health promotion, strategies for program implementation, and gaps in research may be a successful approach for lifelong cardiovascular health.

Botox Injections Explored to Cut Postop Atrial Fibrillation in Cardiac Surgery

Findings of early trials based on epicardial fat pad injections during cardiac surgery.

Subclinical Myocardial Inflammation Common in Rheumatoid Arthritis

Data show that myocardial inflammation in rheumatoid arthritis is related to disease activity and may contribute to increased risk for heart failure.

Skin Autofluorescence Predicts T2DM, Heart Disease, Mortality

Prediction independent of traditional risk factors such as MetS, glucose, HbA1c in general population.

Marathon Runners Show Markers of Cardiac Strain

Amateur marathoners had highest troponin I and T vs half-marathon and 10-km racers.

Younger Patients Account for Increasing Proportion of AMI

Increase especially great among women, who were less likely to receive guideline-based treatment.

Mediterranean Diet, Physical Activity Effective for Weight Loss, Decreased Cardiovascular Events

A 12-month intensive lifestyle intervention including an energy-restricted Mediterranean diet, increased physical activity, and behavioral support for overweight/obese patients was found to be beneficial in decreasing adiposity and cardiovascular events.

ASH: New Venous Thromboembolism Clinical Practice Guideline

The guidelines were developed by over 100 experts, including hematologists, patient representatives, and other specialists.

ACC Releases Consensus Decision Pathway for CVD Risk Reduction in T2D and ASCVD

The American College of Cardiology published an expert consensus statement regarding decision considerations for novel cardiovascular risk reduction therapies in patients with type 2 diabetes and atherosclerotic cardiovascular disease.

Several Risk Factors More Strongly Linked to MI in Women

Blood pressure, smoking, type 1 and 2 diabetes linked to higher hazard ratios for women than men.

Climate Change Ups Heat Deaths, Especially Among Elderly

More people vulnerable to heat exposure, potentially causing heat stress, heart and kidney disease.

Vitamin D Levels Linked to Cardiorespiratory Fitness

Individuals in top quartile of vitamin D levels have significantly higher CRF than those in lowest quartile.

Clinical Decision Support System Ups Outpatient PE Management

Home discharge rate increased at intervention sites; no increase in return visits, adverse outcomes.

Smoke-Free Policies Linked to Lower Systolic Blood Pressure

Lower systolic BP found for those living in areas with public smoke-free policies.

Arterial Stiffness May Predict Dementia Risk

Adjustment for subclinical brain disease markers did not reduce link between arterial stiffness, dementia.

Gender Differences in ASCVD Care, Quality of Life, and Outcomes

Women with ASCVD are at an increased risk for poor patient experience, lower health-related QOL, and inferior perception of their health compared with men.

Empagliflozin Effectively Reduces Risk for Heart Failure Hospitalization

Approximately 50% of deaths in people with type 2 diabetes worldwide, and approximately two-thirds of deaths in people with type 2 diabetes in the US are caused by cardiovascular disease.

Vitamin D Plus Calcium Supplementation May Not Modify Atrial Fibrillation Risk

Baseline serum 25(OH)D level was not predictive of long-term incident atrial fibrillation risk.

Onset of Musculoskeletal Adverse Events Varies Between Statins

Significantly faster onset with atorvastatin, rosuvastatin vs simvastatin during monotherapy.

Curcumin Not Beneficial For Reducing Inflammation, Postoperative Complications Following Elective Abdominal Aortic Aneurysm Repair

Researchers found that, compared with placebo, perioperative oral curcumin did not affect the inflammatory response and risk of postoperative complications after elective abdominal aortic aneurism repair.

Use of Both Aspirin and NSAIDs Associated With Incident Heart Failure Risk

The use of both NSAID and aspirin was positively associated with incident HF in adults with no prior history of CVD.

Heart Disease Leading Cause of Death in Low-Income Counties

Greatest shift to cancer as leading cause of death seen in highest-income counties in United States.

AHA: Limited Benefit for n-3 Fatty Acids in CVD, Cancer Prevention

Second study shows no significant results for vitamin D supplementation vs placebo.

AHA/ACC Release Updated Guidelines for Cholesterol Management

Updated cholesterol guidelines offer more personalized cardiovascular disease risk assessment.

Does Antihypertensive Therapy Reduce CVD Risk in Low-Risk Patients With Mild Hypertension?

Treatment of low-risk patients presenting with mild hypertension with antihypertensive medication should be done with caution.

ACC/AHA/HRS Release Updated Bradycardia Diagnosis and Management Guidelines

The American College of Cardiology, the American Heart Association, and the Heart Rhythm Society have released a guideline on the evaluation and management of patients with bradycardia and cardiac conduction delay.

Type 2 Diabetes May Have Adverse Effect on Parkinson Disease Symptoms, Outcomes

Patients with both Parkinson disease and type 2 diabetes were more likely to have cardiovascular comorbidities than those with only Parkinson disease.

Nonadherence, Discontinuation of Statins High in 1st Year of Prescription

Among older adults prescribed statins, diabetes, anxiety linked to nonadherence, discontinuation.

Some Weather Conditions Linked to Myocardial Infarction Risk

Certain weather conditions are associated with an increased risk for myocardial infarction.

ASN: Aggressive Control of BP, Lipids in T2DM May Up Kidney Risk

Intensive blood pressure control and fenofibrate use in patients with type 2 diabetes who are at high risk for cardiovascular disease may increase the risk for adverse kidney events.

Disagreements in Blood Pressure Guidelines Lead to Physician, Patient Confusion

Discord among international, organizational blood pressure guidelines have led to confusion between physicians and patients alike.

Tibia Lead Levels Linked to Risk of Resistant-Hypertension

Tibia lead levels are associated with resistant-hypertension.

Severity of Metabolic Syndrome Indicates Risk for T2D, CVD in Prediabetes Treatment

Researchers analyzed how improvements in metabolic syndrome may impact the risk of developing type 2 diabetes and cardiovascular disease in patients with prediabetes.

Atherosclerosis Progression Differs According to Timing of Estradiol Therapy After Menopause

Higher levels of estradiol were inversely associated with carotid artery intima-media thickness progression in the early postmenopausal cohort but positively associated with it in the late postmenopausal group.

Preeclampsia Tied to Increased Risk for Vascular Dementia

Preeclampsia seems to be associated with an increased risk for dementia, especially vascular dementia, with a stronger correlation for late-onset disease.

AF Patients With Cancer Less Likely to See Cardiologist

Those who do see a cardiologist are more likely to fill anticoagulant prescription and have reduced risk for stroke.

Aspirin, Anticoagulants Similarly Prevent VTE After TKA

Among patients undergoing total knee arthroplasty, aspirin alone may provide protection against postoperative venous thromboembolism that is similar to that of other anticoagulants.

Harvard: Heart Researcher's Papers Contain Fraudulent Data

31 scientific publications from the laboratory of Piero Anversa contain falsified and/or fabricated data.

High Risk for Readmission for Takotsubo Syndrome

Of TTS survivors, 11.9% readmitted within 30 days, with associated mortality of 3.5%.

β-Blockers in Early Pregnancy Not Linked to Significant Risk for Overall, Cardiac Malformations

The use of β-blockers in the first trimester of pregnancy may not greatly increase the risk for major congenital malformations in offspring.

CDC: Many Children With Heart Conditions Have Special Needs

One in 77 US children reportedly had heart conditions in 2016, with special needs in 60%.

Empagliflozin Impact on Life Expectancy Examined in T2DM Patients With CVD

For this analysis, the authors used follow-up data from all 7020 patients included in the EMPA-REG OUTCOME trial to estimate the effect of empagliflozin on all-cause mortality vs placebo over the duration of a patient's lifetime.

Wall Thickness Measured by MRI More Consistently Linked to CVD

Common carotid artery wall thickness measured using magnetic resonance imaging is more consistently associated with incident cardiovascular disease outcomes than intima-media thickness measured by ultrasound.

Updated Hypertension Guideline Directs Treatment to Those With High CVD Risk

Implementing ACC/AHA guideline would direct antihypertensive meds to adults at high CVD risk.

Morbidity, Mortality Up for Youth With CHD Presenting to ED

Children with congenital heart disease presenting to ED at increased risk for morbidity, mortality.

Lixisenatide Cuts Kidney Damage in Type 2 Diabetes and Coronary Syndrome

Lixisenatide reduces progression of urinary albumin-creatinine ratio in patients with macroalbuminuria.

Family History Linked to Early-Onset A-Fib in Minorities

Probands of African or Hispanic/Latino descent with early-onset atrial fibrillation are more likely than European Americans to have a first-degree relative with AF.

Diabetes Common in Patients With Ischemic, Hemorrhagic Stroke

Approximately 28% of stroke patients have diabetes, and the presence of diabetes can increase the risk for poor stroke outcome.

Southern Dietary Pattern Mediates Racial Difference in Hypertension

For both men and women, Southern dietary pattern is largest mediating factor for difference in hypertension.

Switching IV to Oral Antibiotics Noninferior for Some Endocarditis Events

For certain patients with endocarditis on the left side of the heart under stable condition, switching from intravenous (IV) antibiotics to orally administered antibiotics is noninferior to staying on IV treatment.

Risk of Venous Thromboembolism Recurrence High

At 6 months, rates for provoked, unprovoked, cancer-related VTE are 6.8, 6.92, 9.06 per 100 person-years.

Guidelines Updated for Adult Congenital Heart Disease

New classification system intended to capture complexity of anatomy and physiology of ACHD.

Policies Should Encourage Healthy Food Consumption

Aim should be to prevent CVD with environment where healthy foods are accessible, desirable.

Lorcaserin Facilitates Weight Loss in Overweight, Obese

Increased weight loss vs placebo with no rise in rate of extended major cardiovascular events.

Enlarged Kidneys in Neonates With Congenital Heart Disease

Kidneys of neonates with left heart obstruction consistently found to be larger than normal.

Risk Factors for Atherosclerotic Cardiovascular Disease in the South Asian Population

South Asians exhibit the highest rates of ASCVD among all ethnic groups, and the highest prevalence is in younger age groups; up to 25% of myocardial infarctions in India occur in individuals younger than 40 years of age.

New Risk Factors Identified for Varicose Vein Disease

Mendelian randomization analysis provides evidence that increased height causally tied to varicose veins.

Including Hypertensive Disorders of Pregnancy in CVD Risk Score Does Not Improve CVD Risk Prediction

Adding history of hypertensive disorders of pregnancy to the current cardiovascular disease (CVD) risk score does not improve CVD prediction in low-risk women.

No Clear Benefit for Rivaroxaban After Hospital Discharge

Incidence of major bleeding low with rivaroxaban, but clot risk not lower.

Intensive Blood Pressure Therapy Lowers Cardiovascular Risk in Diabetes

Intensive blood pressure therapy is associated with a significantly lower risk for serious cardiovascular events in the adults with diabetes.

ASPREE Trial: Aspirin Associated With Higher Mortality, Hemorrhage Risk in Older Adults

The use of aspirin in healthy elderly patients as a preventative strategy was associated with no prolongation of long-term disability-free survival compared with placebo.

Prurigo Nodularis More Likely in African-Americans

PN linked to chronic kidney disease, hepatitis C, congestive heart failure, HIV, psychiatric comorbidities.

AHA: Resistant Hypertension Diagnosis, Treatment Guidelines Updated

Ruling out prescription non-compliance, white coat syndrome, and interfering medications necessary.

Single, Fixed-Dose Combo Pills Improve Hypertension Outcomes

Findings show improved outcomes may be due to better medication adherence.

AHA: Update on Diagnosis, Treatment for Chagas Cardiomyopathy

Prevalence has increased in US; statement aims to increase recognition, improve care.

Increased Dairy Consumption Linked to Reduced CVD, Mortality Risk in Low-, Middle-Income Countries

The consumption of whole-fat dairy products may reduce cardiovascular disease and mortality risk, contrary to current dietary guidelines that advise limited consumption of fat-free or low-fat dairy products.

Reducing HF Hospitalization Risk: Antidiabetic Drug Classes Compared

The authors searched for randomized placebo-controlled trials (December 1, 2008 to November 24, 2017) involving 3 pharmacologic classes of antidiabetic medications to compare the effects of these agents on the risk of hospitalization for HF in T2DM patients.

Labor Induction Linked to Hypertensive Complication Prevention in Women With Chronic Hypertension

For expectant mothers with chronic hypertension, labor induction after 38 weeks of gestation may prevent hypertensive complications without increasing the risk of cesarean delivery.

New Guidelines Target Pharmacological Hypertension Management to High-Risk Patients

A guideline-based approach directing pharmacological treatment to adults more likely to have CVD events may maximize absolute risk reduction of treatment.

Excess Cardiac Risk Varies With Age of Onset of T1D

Excess risk differed by up to 5 times across different diagnosis age groups.

Assessing the Evidence of Aspirin for Primary Prevention in Diabetes

The substantial burden of cardiovascular disease in patients with diabetes has led to the exploration of various cardiovascular disease prevention strategies, including the use of aspirin.

CHEST Releases Guideline for Antithrombotic Therapy in Atrial Fibrillation

Patients with atrial fibrillation who have ≥1 non-sex CHA2DS2VASc stroke risk factor should receive oral anticoagulation as antithrombotic therapy.

Laryngeal Tube Insertion Beats Endotracheal Intubation in OHCA

And, 30-day functional outcomes similar with supraglottic airway device or tracheal intubation.

High LDL in Young, Healthy Adults Leaves Them Vulnerable to CVD

Findings may have implications for future cholesterol treatment paradigms.

Lower Long-Term Survival for In-Hospital Cardiac Arrests in Blacks

Black survivors of in-hospital cardiac arrest have lower survival at 1, 3, 5 years vs whites.

AHA/ACC: Updated Management Guidelines for Adult Congenital Heart Disease

The American College of Cardiology and American Heart Association developed updated guidelines on the evaluation, management, and monitoring of adults with congenital heart disease.

Triple Combo Blood Pressure Pill Can Improve BP Control

Proportion achieving target BP increased with use of triple combo pill vs usual care at 6 months.

Perspectives on USPSTF AF Screening Recommendation

Physicians weigh in on the need to develop a screening strategy.

Healthy Lifestyle With Diabetes Cuts Cardiovascular Risk

Benefit seen for adoption of healthy lifestyle even after T2DM diagnosis made.

AHA: A Diverse Diet May Not Promote a Healthy Weight

American Heart Association science advisory recommends healthy eating patterns instead.

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