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Clinical Quiz

Derm Dx: A diffuse erythematous rash that blanches with pressure

An 8-year-old child presents with a diffuse erythematous made up of punctate popular elevations the size of pinheads that blanche with pressure. The rash began with flushing of the cheeks and forehead and rapidly spread to the trunk and extremities, where it is most marked on the inguinal, axillary, antecubital and abdominal areas. Rash onset…

Derm Dx: Unexplained blisters, primarily on the hands and feet, develop into mild ulcerations and heal without scarring

A child presents with recurrent unexplained blister formation, primarily on the hands and feet that develop into mild ulcerations and heal without scarring. Smaller erosions and vesicles are present on the elbows, arms and shoulders, and the patient has lost several fingernails and toenails. Family history is negative for psoriasis and atopy. What’s your diagnosis?…

Derm Dx: Erythematous, indurated lesions on the face and extremities

A patient presents with erythematous, indurated lesions on the face and extremities that are ulcerated and discharging pus accompanied by low-grade fever, chest pain, cough and hemoptysis. What’s your diagnosis?Submit your answer and read the full explanation below. If you like this activity or have a suggestion, tell us about it in the comment box…

Papules grow to cover patches below knees

A white woman aged 45 years presented with multiple plaques on the anterior and lateral aspects of her lower legs. The lesions began as erythematous papules that enlarged over the past few years to form plaques with raised borders and depressed centers. The patient reported no pain or pruritus. Examination showed multiple well-demarcated plaques with…

Itchy facial rash spread to back and chest

A woman aged 29 years presented with a mildly pruritic facial rash that started suddenly two weeks earlier and spread to her upper chest and upper back over the course of several days. Coincident with the onset of the rash, she experienced malaise, fatigue, and chills that were self-treated with OTC flu medication. Medical and…

Derm Dx: A painful red or purplish rash spreads and blisters

A patient presents with flu-like symptoms, followed by onset of a painful red or purplish rash that spreads and blisters, and may cause the top layer of skin to die and shed. What’s your diagnosis?Submit your answer and read the full explanation below. If you like this activity or have a suggestion, tell us about…

Derm Dx: A single chancre progresses to a diffuse rash

A single chancre that progresses to a diffuse rash made up of macular, discrete, reddish-brown lesions, ≤5 mm diameter. The rash may be accompanied by malaise, fever, myalgias, arthralgias and lymphadenopathy. This eventually progresses to a granuloma made up of necrotic tissue with a rubbery texture. What’s your diagnosis?Submit your answer and read the full…

Derm Dx: Itchy, red patches on the face and nose

A swollen, red, warm, hardened and painful rash with sharply demarcated advancing margins that can appear on the face and spreads across the cheeks and bridge of the nose. Rash onset occurs after an initial 48-hour period in which symptoms including high fever, shaking, chills, fatigue, headaches and vomiting develop. The patient’s lymph nodes may…

Multiple erosions and shallow ulcerations fo the cutaneous and mucosal lips, gingiva and hard palate in an elderly woman. The erosions extended superiorly to the perinasal area and many were covered with hemorrhagic crust.

Painful ulcers on the lips and tongue

Clinical descriptionAn elderly white woman was admitted to the hospital for management of an acute exacerbation of chronic obstructive pulmonary disease. Her treatment includes oxygen, inhaled bronchodilators, antibiotics, and oral corticosteroids. The patient’s respiratory status was improved three days after admission, but she noted new painful ulceration of the lips and tongue. She also reported…

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