Findings for those with systolic BP 130 mm Hg at age 50 years
Administering a visual association test in patients with a small decline on the Mini-Mental State Examination during a 2-year period has substantial incremental value for identifying those at elevated risk for developing dementia.
Anticholinergic drugs for depression, urologic conditions, or Parkinson disease are associated with potential dementia occurrences up to 20 years after drug exposure.
Review of 4 studies shows positive link for clinically significant anxiety in midlife, future dementia
Alcohol use disorders are the strongest modifiable risk factors for onset of all types of dementia, especially early-onset dementia.
Apathy and depressive symptoms are independently associated with incident dementia in community-dwelling older people.
Higher BMI is associated with increased dementia risk when weight was measured more than 20 years before dementia diagnosis, but this association is reversed when BMI was assessed less than 10 years before dementia diagnosis.
Among women, but not men, mid-adulthood hypertension correlated with a 65% increased dementia risk.
Birth in a high stroke mortality state was associated with a significantly increased risk of dementia.
However, those who used PPIs were also more likely to use anticholinergic medicines that have been linked to cognitive difficulties.
Results from a 27-year follow-up study found no association between physical activity and a lower risk of dementia.
Regular proton pump inhibitor use in the elderly was associated with an increased risk of incident dementia compared with no proton pump inhibitor use, according to researchers.
The prevalence of dementia dropped about 24% between 2000 and 2012.
Facing dementia with strength and courage can inspire and comfort patients' families.
Both prescription and OTC proton pump inhibitors have been linked to an increased risk for development of dementia.
Patients administered low doses of benzodiazepines have an elevated risk of dementia and Alzheimer's disease compared with patients who received higher doses.
People who lose greater amounts of weight per decade later in life have an increased risk of mild cognitive impairment.
Older adults with dementia who took cholinesterase inhibitors had an increased risk of weight loss.
Diabetes patients who had a greater number of diabetes-related complications had an increased risk for dementia.
Research findings suggest the link between dementia risk and anticholinergic medications may persist and may not be reversible years after people stop taking these drugs.
Many nursing home residents incur substantial costs associated with questionable medication prescriptions.
The odds of severe memory impairment more than doubled with a history of alcohol use disorders.
Leisure-time physical activity has previously been shown to have a positive impact on health.
After adjustments, researchers suggest psychosocial and life-style related risk factors may be modifiable targets for intervention.
The AAPA's Clinical Health Affairs Commission cites childhood immunization, post-traumatic stress disorder, obesity, celiac disease and dementia as topics to watch in 2013.
Among metabolically abnormal individuals, the obese showed faster global cognitive decline.