Depression

Work Instability Linked to Fatigue, Depression in Ankylosing Spondylitis

Work Instability Linked to Fatigue, Depression in Ankylosing Spondylitis

Fatigue and depressive symptoms had a negative effect on work stability in patients with ankylosing spondylitis.

Pharmacogenomic-Guided Care May Improve Clinical Outcomes in MDD

Pharmacogenomic-Guided Care May Improve Clinical Outcomes in MDD

Weighted and combined multi-gene pharmacogenomic testing significantly increased clinical response and remission rates for patients with major depressive disorder.

Higher Risk for Depression, Anxiety Seen With Cerebral Palsy

Higher Risk for Depression, Anxiety Seen With Cerebral Palsy

Association seen in patients with cerebral palsy without accompanying intellectual disability.

Web-Based Treatments for Depression in HIV-Infected Individuals

Web-Based Treatments for Depression in HIV-Infected Individuals

Depression is a common comorbidity in people living with HIV, with lifetime prevalence estimates ranging from 22% to 61%.

Long-Term Lithium Use: More Evidence Needed to Associate With Cancer Risk

Long-Term Lithium Use: More Evidence Needed to Associate With Cancer Risk

The European Medicine Agency has reported that there may be an association between long-term lithium use and reports of both renal tumors and thyroid cancer.

Patient Management During the Holiday Season: What Clinicians Should Know

Patient Management During the Holiday Season: What Clinicians Should Know

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Although the holiday season may be joyous for some, others may feel the sting of depression; therefore, it is important to monitor patients during this time of year.

Limiting Social Media May Improve Psychological Well-Being

Limiting Social Media May Improve Psychological Well-Being

Limiting exposure to 30 minutes per day cut loneliness and depression in undergraduates.

For Teen Girls, Depression May Predict Subsequent Alcohol Use

For Teen Girls, Depression May Predict Subsequent Alcohol Use

Depression severity predicts increased likelihood of alcohol use; link for reverse pathway inconsistent.

Peer Support Reduces Hospitalizations in People With Diabetes and Depression

Peer Support Reduces Hospitalizations in People With Diabetes and Depression

Patients with diabetes and depressive symptoms who received community-based peer support for diabetes management reported less frequent acute care visits and hospitalizations than patients with diabetes without depressive symptoms.

Rates of Mental Health Treatment, Diagnosis Up for College Students

Rates of Mental Health Treatment, Diagnosis Up for College Students

2007 to 2017 also saw increases in depression and suicidality, while decrease observed in stigma.

Oral Therapy for Suicidal Bipolar Depression Gets Breakthrough Designation

Oral Therapy for Suicidal Bipolar Depression Gets Breakthrough Designation

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NRX-101 combines D-cycloserine (DCS), an N-methyl-D-aspartate (NMDA) receptor antagonist, and lurasidone, a D2/5-HT2a receptor antagonist.

Buprenorphine, Samidorphan Helpful in Refractory Depression

Buprenorphine, Samidorphan Helpful in Refractory Depression

An adjunctive buprenorphine/samidorphan combination seems beneficial for patients with major depressive disorder with inadequate response to antidepressant therapy.

Poor Diet, Physical Activity Behaviors May Lead to Metabolic Syndrome in Depression

Poor Diet, Physical Activity Behaviors May Lead to Metabolic Syndrome in Depression

Investigators examine the association between depression and metabolic syndrome, factoring in diet and physical activity.

Plant-Based Diets Beneficial for Adults With Type 2 Diabetes

Plant-Based Diets Beneficial for Adults With Type 2 Diabetes

For adults with type 2 diabetes, plant-based diets can improve psychological health, quality of life, hemoglobin A1c levels.

Postpartum Pain Associated With Increased Risk for Postpartum Depression

Postpartum Pain Associated With Increased Risk for Postpartum Depression

Patients at high risk for postpartum depression may need denser analgesia control after delivery.

Probiotics, Depression, and the Role of Inflammation

Probiotics, Depression, and the Role of Inflammation

Researchers examined evidence suggesting that probiotics may exert antidepressant effects via anti-inflammatory mechanisms.

High Burden of Depression, Anxiety Reported Among Adults With Arthritis

High Burden of Depression, Anxiety Reported Among Adults With Arthritis

Data from the CDC show that the prevalence of anxiety and depression is higher among adults with arthritis compared with the general population.

Retirement Associated With Increased Risk for Depressive Symptoms

Retirement Associated With Increased Risk for Depressive Symptoms

Employment status displayed a lagged effect on depression, with retirement preceding higher levels of depression 2 years after initial retirement status report.

Improvement in Guidelines for Monitoring Patients Receiving Lithium Essential

Improvement in Guidelines for Monitoring Patients Receiving Lithium Essential

The quality of patient monitoring may improve if the clinical practice guidelines are improved, as many healthcare professionals use the guidelines in their monitoring of patients taking lithium.

Discrepancy Between Primary Care Screening for Alcohol Use and Screening for Depression

Discrepancy Between Primary Care Screening for Alcohol Use and Screening for Depression

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Screening of adult patients with significant depressive symptoms is often inadequate in the primary care setting, especially among those with hazardous alcohol consumption.

Light Therapy Offers Nonpharmacologic Treatment for Perimenopausal Depression

Light Therapy Offers Nonpharmacologic Treatment for Perimenopausal Depression

Light treatments successfully corrected abnormal timing of melatonin circadian rhythms in perimenopausal women with depression and improved mood and sleep within 2 weeks.

Selective Serotonin Reuptake Inhibitors May Increase Risk for Suboptimal Fetal Growth

Selective Serotonin Reuptake Inhibitors May Increase Risk for Suboptimal Fetal Growth

Use of serotonin reuptake inhibitors for maternal depression may increase the risk for low birth weight in children.

Effects of Pain, Depression, and Insomnia on Health Care Use in Older Adults With Osteoarthritis

Effects of Pain, Depression, and Insomnia on Health Care Use in Older Adults With Osteoarthritis

The combined effects of pain with insomnia and pain with depression increased diverse types of health care use.

Perinatal Photoperiod May Influence Lifetime Depression in Offspring

Perinatal Photoperiod May Influence Lifetime Depression in Offspring

Extreme differences in daily photoperiod during pregnancy may be related to risk for lifetime depression in offspring.

Combinatorial Pharmacogenetics Useful in Treatment for Depression

Combinatorial Pharmacogenetics Useful in Treatment for Depression

These data support the clinical use of combinatorial pharmacogenetics for patients with major depressive disorder.

Guidelines for Managing Perimenopausal Depression Now Available

Guidelines for Managing Perimenopausal Depression Now Available

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The 5 topics addressed by the 11-member expert panel include epidemiology, clinical presentation, therapeutic effects of antidepressants, effects of hormone therapy, and the effectiveness of other therapies (eg, psychotherapy, exercise, natural health products).

Testing the Current Guidelines for Antidepressant Treatment of New Onset Depression

Testing the Current Guidelines for Antidepressant Treatment of New Onset Depression

Investigators determined that titrating sertraline to 100 mg/day vs 50 mg/day for initial antidepressant therapy for a new MDD episode has no added benefit and increases cost.

Parental Depression Ups Odds of Child Use of Health Services

Parental Depression Ups Odds of Child Use of Health Services

Findings seen across spectrum of care -- outpatient, emergency department, inpatient.

Antidepressants and Bleeding Risk: What's the Link?

Antidepressants and Bleeding Risk: What's the Link?

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Results showed an increased risk of bleeding with SRIs by 1.16-2.36 times with an even higher 3.17- to 10.9-fold risk with concomitant NSAIDs.

Prenatal Depression More Common in Young Moms Today

Prenatal Depression More Common in Young Moms Today

Depressed mood more common in young pregnant women today than in their mothers' generation.

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