Diabetes News Archive

ADA, EASD Issue New Recommendations for Type 2 Diabetes

Recommendations for the management of type 2 diabetes have been updated, according to a consensus report by the American Diabetes Association and the European Association for the Study of Diabetes.

Late-Onset Epilepsy Linked to APOE ε4, Smoking, Diabetes

The risk for late-onset epilepsy was lower in patients with higher physical activity levels and moderate alcohol intake.

Better Glycemic Control With Closed-Loop Insulin Delivery

Day-and-night hybrid closed-loop insulin delivery improves glucose control compared with sensor-augmented pump therapy.

Diabetes Common in Patients With Ischemic, Hemorrhagic Stroke

Approximately 28% of stroke patients have diabetes, and the presence of diabetes can increase the risk for poor stroke outcome.

CPAP for OSA Does Not Improve Diabetic Macular Edema or Visual Acuity

Continuous positive airway pressure for obstructive sleep apnea in patients with type 2 diabetes offered no improvement in visual acuity compared with usual care alone.

Combination Immunosuppressive Therapy Beneficial for Type B Insulin Resistance

A combined immunosuppressive regimen was found to be a highly effective and safe treatment for patients with type B insulin resistance.

Participation Up With Online Diabetes Prevention Program

But weight loss no different for online, in-person DPP for obese/overweight veterans with prediabetes.

Total Diabetes at 14% in US Adults for 2013-2016

Prevalence of diagnosed and undiagnosed diabetes 9.7 and 4.3%; prevalence increased with age.

Lower Hypoglycemia Risk, Greater Weight Loss With SGLT2 Inhibitor, Sulfonylurea in T2D

SGLT-2i exhibited superior effects in terms of weight loss and did not increase the risk for hypoglycemia in dual therapy with sulfonylurea.

Poor Glycemic Control Associated With Higher Risk for Dementia in Older Adults With T1D

Repeated exposure to high levels of HbA1c was associated with increased risk for dementia in a cohort of patients age ≥50 with type 1 diabetes.

Intensive Blood Pressure Therapy Lowers Cardiovascular Risk in Diabetes

Intensive blood pressure therapy is associated with a significantly lower risk for serious cardiovascular events in the adults with diabetes.

Higher Aldosterone Levels Tied to Incident Type 2 Diabetes Risk

Racial/ethnic differences seen in the association of aldosterone with incident type 2 diabetes.

T1D, Poor Glycemic Control Linked to Infection Development

Researchers found that patients with T1DM and poor glycemic control were more frequently diagnosed with infections.

Excess Cardiac Risk Varies With Age of Onset of T1D

Excess risk differed by up to 5 times across different diagnosis age groups.

FDA: Cases of Rare Gangrene of Genital Area Tied to Diabetes Drug Class

The infection developed within several months of the patients starting SGLT2 therapy and the drug was discontinued in most cases. All patients required surgery and there was 1 reported death.

Assessing the Evidence of Aspirin for Primary Prevention in Diabetes

The substantial burden of cardiovascular disease in patients with diabetes has led to the exploration of various cardiovascular disease prevention strategies, including the use of aspirin.

PedsQL 3.2 Diabetes Modules Display Excellent Measurement Ability

The PedsQL 3.2 can assist in identify new and existing therapeutic interventions for individuals with different diabetes-specific health-related quality of life profiles.

Medicaid Expansion Linked to Increase in Diabetes Prescription Fills

Fills for insulin and newer medications increased by 40 and 39%, respectively.

High Prevalence of Diabetes in Those With Severe Mental Illness

Prevalences of diabetes and prediabetes higher among racial/ethnic minorities with mental illness.

Treating Painful Diabetic Peripheral Neuropathy With Electroacupuncture

Investigators sought to determine the safety and efficacy of electroacupuncture for painful diabetic peripheral neuropathy.

Two Strategies for Preventing Diabetes in Minority Patients

Physicians can stress the factors in a patient's control and change messaging about the condition.

FDA to Review Gimoti for Diabetic Gastroparesis in Adult Women

The FDA has set a Prescription Drug User Fee Act target date of April 1, 2019.

Fasting Insulin vs Hemoglobin A1c: Are We Getting It Right?

The early diagnosis and management of prediabetes will have a significant impact on patient outcomes and healthcare spending.

Low-Carb Diet May Reduce HbA1c More Than Low-Fat Diet in T2D

Investigators compared low-carbohydrate with low-fat diet on glucose control and other metabolic and anthropometric variables in T2D.

Hepatic Markers Linked to Early Predictors of Type 2 Diabetes Risk in Women

Circulating hepatic markers may predict the risk for diabetes in women.

FDA Approves FreeStyle Libre 14 Day Flash Glucose Monitoring System

The new Flash Glucose Monitoring System enables patients to wear the sensor for up to 14 days compared with the existing FreeStyle Libre System that was approved for 10-day wear.

Independent Relationship Between CV Mortality, Oxidative DNA Damage in Type 2 Diabetes

This represents the prospective study confirming an independent relationship between cardiovascular mortality and oxidative DNA damage in type 2 diabetes.

Basal Insulin Analogs vs NPH Insulin to Reduce Hypoglycemia-Linked ED Visits in T2D

Compared with human neutral protamine Hagedorn insulin, basal insulin analogs do not reduce risk of hypoglycemia-linked ED visits or hospital admissions in T2D.

Diabetes Diagnosis May Impact Health Behaviors of Family

Small changes in health behaviors seen for partners of those newly diagnosed with diabetes.

NP, PA Treatment Comparable for Patients With CVD or Diabetes

Effectiveness of care and healthcare resource use for diabetes or cardiovascular disease were comparable among patients receiving care from an NP vs those managed by a PA.

Link Between Bullous Pemphigoid and Dipeptidyl Peptidase-4 Inhibitors

The relationship between bullous pemphigoid and dipeptidyl peptidase-4 inhibitors in type 2 diabetes.

Continuous Subcutaneous Insulin Infusion May Reduce Basal Hyperglycemia in T2D

Patients with type 2 diabetes who were initially treated with multiple daily injections were assessed before and after switching to continuous subcutaneous insulin infusion.

1996 to 2013 Saw Large Increase in Diabetes Spending

Increased spending per encounter has been the biggest driver of overall rise in spending.

Diabetes Risk Associated With Cirrhosis, Not Chronic HCV Infection, in HIV Positive Patients

Cirrhosis is associated with an increased risk for diabetes mellitus among patients living with HIV.

Empagliflozin Reduces Risk for Nephropathy Regardless of Blood Pressure, LDL Cholesterol, HbA1c

Investigators examined renal outcomes when controlling cardiovascular risk factors, such as blood pressure, LDL-C, and HbA1c.

Risk for Below Knee Amputations With Canagliflozin vs Other Antihyperglycemic Agents

Investigators analyzed real world data to examine the risk for below-knee amputations in patients with type 2 diabetes taking canagliflozin vs other medications.

Beta-Blockers Show Varied Effects on Hypoglycemic Mortality Risk in Diabetes

Investigators examined the relationship between the use of β-blockers and incidence of hypoglycemia and risk for mortality in hospitalized patients with diabetes.

Pen vs Patch Bolus Insulin Delivery for T2D Using CGM

Investigators compared 2 methods of delivering bolus insulin, pen vs patch, using metrics from continuous glucose monitoring.

Liraglutide May Prevent Dementia in Elderly With Type 2 Diabetes

Investigators examined the efficacy of liraglutide for the prevention of dementia in elderly patients with type 2 diabetes.

Age, Baseline HbA1c May Predict Glycemic Control in Newly Diagnosed Type 2 Diabetes

Investigators examined the effectiveness of oral agents vs insulin as an initial treatment option for people newly diagnosed with type 2 diabetes.

Elevated Triglycerides, Diabetes May Be Predictors of Major Cardiovascular Events

Investigators examined cardiovascular outcomes in patients with elevated triglyceridemia and diabetes treated with statins.

Safety and Performance of Omnipod HCL for Children With Type 1 Diabetes

In children with type 1 diabetes, the Omnipod hybrid closed-loop personal model system was safe and performed well.

Type 2 Diabetes Does Not Affect Pneumonia Incidence, Outcomes After Stroke

Investigators examined the incidence and outcomes of pneumonia in patients with acute ischemic stroke and type 2 diabetes.

ITCA 650 Shows Efficacy in Reducing Weight, HbA1c in Type 2 Diabetes

The ITCA 650, a small titanium osmotic mini-pump, provides a subcutaneous infusion of exenatide over 3 or 6 months.

MEDI0382 Safe, Effective for Normalizing Glucose, Weight Loss in Type 2 Diabetes

MEDI0382 reduced body weight and normalized fasting and postprandial blood glucose levels in patients with type 2 diabetes.

Chronic Kidney Disease More Common in Type 2 Diabetes Than in Type 1 Diabetes

Investigators examined the prevalence of chronic kidney disease in adults with type 1 diabetes compared with type 2 diabetes.

Implantable Continuous Glucose Monitoring Device Safe, Effective for Adolescents

The safety assessment included incidence of insertion or procedure-related removal and device-related serious adverse events through 180 after insertion.

BCG Vaccine Tied to Reduced Hyperglycemia in Type 1 Diabetes

Systemic shift in glucose metabolism from oxidative phosphorylation to aerobic glycolysis.

Cleared Blood Glucose Monitor Systems Not Always Accurate

Six of 18 systems met predetermined accuracy standard in three of three studies

Sodium Chloride Fluid Infusion Rates Do Not Affect Pediatric Diabetic Ketoacidosis

Sodium chloride content of intravenous fluids does not affect neurologic events in children with diabetic ketoacidosis.

Long-Term Type 1 Diabetes Associated With Cognitive Decline

Deficits similar for long-term type 1 diabetes and age-matched patients with type 2 diabetes

Cancer Development Linked to Increased Diabetes Risk

Increased risk of subsequent diabetes independent of traditional diabetes risk factors

More Rapid Decline in Kidney Function for Diagnosed Diabetes

Much steeper decline in adjusted mean eGFR for those with diagnosed diabetes versus those without

Improving Insulin Access: ADA Public Policy Recommendations

The American Diabetes Association (ADA) has released a public policy statement that outlines long- and short-term recommendations for improving insulin affordability.

US Nursing Home Costs Due to Diabetes Vary Greatly by State

Per-person diabetes-attributable costs ranged from 374 in New Mexico to 1,610 in Washington, D.C.

Diabetes and Mortality: Comparing SGLT-2 Inhibitors, GLP-1 Agonists, and DPP-4 Inhibitors

For patients with type 2 diabetes, sodium-glucose cotransporter 2 inhibitors and glucagon-like peptide 1 agonists significantly reduce mortality rates compared with dipeptidyl peptidase 4 inhibitors.

Diabetes Prevalence by Type in the United States: CDC report

The CDC conducted a study to estimate the prevalence of diagnosed diabetes among adults in 2016 by primary type.

FDA Approves AI Device to Detect Diabetic Retinopathy

Artificial intelligence software that can detect diabetic retinopathy has been approved by the U.S. Food and Drug Administration.

Eating Pecans May Cut Risk of Cardiovascular Disease, Diabetes

Benefits seen in markers of cardiometabolic disease, including insulin sensitivity

ACP supports higher HbA1c targets for pharmacotherapy in adults with T2D

ACP responds to criticism from the ADA, the Endocrine Society, the AACE, and the AADE of guidance that clinicians should aim to achieve an HbA1c level between 7% and 8% in most people with type 2 diabetes.

Early Care Transitions Beneficial for Adolescents with Type 1 Diabetes

A diabetes transition registry may help adolescents with type 1 diabetes plan and prepare for independent adult care.

Better glycemic control, weight reduction with surgical treatment for youths with T2D, severe obesity

For adolescents with type 2 diabetes and severe obesity, surgical therapy facilitates glycemic control and weight reduction better than medical therapy.

High fiber diet beneficial for gut bacteria development in type 2 diabetes

A high fiber diet promotes gut bacteria that helps blood glucose control in patients with type 2 diabetes.

New type 2 diabetes guideline recommends more moderate HbA1c target

The American College of Physicians has developed recommendation statements to guide clinicians in selecting targets for pharmacologic treatment of type 2 diabetes.

HbA1C levels linked to cognitive decline in diabetes

HbA1C, diabetes status, and cognitive decline during a span of 10 years were compared using data from the English Longitudinal Study of Ageing.

Standards of Medical Care in Diabetes modified for cardiovascular disease

The ADA's updates include a modified patient-focused care algorithm as well as improved risk management for CVD.

FDA approves shock wave device to treat diabetic foot ulcers

The FDA has approved the Dermapace System for treatment of chronic, full-thickness diabetic foot ulcers.

FDA approves new "follow-on" insulin for diabetes

The new FDA approved short-acting insulin drug can be used to treat T1 and T2 diabetes.

Type 2 diabetes may be reversed with weight loss, physician care

With the help of a doctor and a weight loss plan, new research suggests type 2 diabetes can be reversed in less than a year.

FDA approves weekly diabetes drug that may also be beneficial for weight loss

The FDA has approved semaglutide injection as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Oral insulin does not prevent type 1 diabetes in relatives of patients

Oral insulin usage does not prevent the development of type 1 diabetes in relatives of patients.

Commercial weight loss program may help prevent diabetes in obese patients

Primary care referral to Weight Watchers meetings is associated with weight loss, HbA1c reduction.

Statins associated with increased risk of diabetes in high-risk individuals

Statins are associated with an increased risk for developing type 2 diabetes, especially for high-risk individuals.

Halloween tips for children with diabetes

With a little creativity, children with diabetes can enjoy the festivities of Halloween.

Antidepressant use linked to type 2 diabetes in young adults

Type 2 diabetes risk is increased in young adults through antidepressant use, specifically the duration of use and the cumulative dose.

Diabetes risk greater in children, young adults on second-generation antipsychotics

Type 2 diabetes is greater with second-generation antipsychotics than with non-second-generation antipsychotic psychotropic medications for patients aged 6 to 25 years.

Insulin pump linked to better glycemic control in young patients with type 1 diabetes

Insulin pump therapy is linked to lower risks of severe hypoglycemia and diabetic ketoacidosis and better glycemic control than insulin injection therapy.

FDA approves glucose monitoring system to eliminate fingerstick testing

The system uses a small sensor implanted below the skin and a mobile reader to continuously monitor blood glucose.

Evidence finds link between antidepressant drug use and type 2 diabetes

After the inclusion of recent negative studies, a statistically significant association between AD use and diabetes was observed.

Gastric bypass surgery effective for weight loss, diabetes prevention for 12 years

The 12-year results show that Roux-en-Y gastric bypass offered long-term durability of weight loss and was associated with fewer obesity-related coexisting conditions compared with those who did not have the surgery.

Managing hypertension in diabetes: a position statement from the ADA

The statement includes advances in care since the ADA's last position statement was published in 2003.

Shorter sleep duration linked to higher diabetes risk in children

Sleep duration for 1 hour longer was associated with lower BMI, fat mass, insulin resistance, and fasting glucose but had no effect on HbA1c or cardiovascular risk.

Lifestyle intervention provides minimal benefit in improving glycemic control in type 2 diabetes

Lifestyle interventions maintain glycemic control in patients with type 2 diabetes.

Regular alcohol consumption associated with lower risk of diabetes

Consumption of alcohol 3 to 4 days weekly is associated with a significantly lower risk for diabetes in men and women.

Maternal lifestyle interventions reduce the odds of cesarean section

Lifestyle interventions reduce gestational weight gain across various subgroups of women and lower the odds of cesarean section without affecting offspring outcomes.

A link between antiretroviral therapy and diabetes in HIV patients?

HIV-infected patients on ART had approximately 4 and 1.5 greater odds of developing diabetes mellitus and metabolic syndrome, respectively.

Degludec vs glargine in type 2 diabetes for cardiovascular events

Degludec is noninferior to glargine regarding the incidence of major cardiovascular events among patients with type 2 diabetes.

Side effects may affect medication nonadherence in patients with chronic disease

Almost half of participants reported that they never received information regarding the side effects of their medication from their prescriber.

Cardiometabolic Disease Staging score calculates diabetes risk in obese individuals

The score can predict the effectiveness of weight-loss therapy for preventing diabetes in overweight or obese individuals.

Depression among diabetes patients may affect long-term drug adherence

Patients exhibiting moderate-to-severe depressive symptoms had worse adherence than nondepressed patients.

Probiotics may lower risk of gestational diabetes

Women who took probiotics in their second trimester had lower rates of gestational diabetes.

Using information technology to tailor diabetes care

A study of one tracking system's effect finds improvement in the management of diabetes.

Anti-inflammatory effects of linagliptin in diabetes patients

Patients taking linagliptin had decreased HbA1c as well as reactive oxygen species generation and plasma lipid peroxide levels.

Insulin pump therapy improves quality of life in adolescents with type 2 diabetes

Adolescents with type 2 diabetes decreased HbA1c levels after using insulin pump therapy for a 3-month period.

Diabetes and glucose intolerance increase with higher outdoor temperature

Diabetes incidence rates in the US and glucose intolerance worldwide increased per 1°C increase in temperature.

Insulin initiation in primary care improves HbA1c levels

The Stepping Up model of care produced a clinically and significantly significant improvement in HbA1c among adults with type 2 diabetes managed in primary care.

Gluten-free diet may increase risk of type 2 diabetes

Individuals who consume the least amount of gluten are more likely to develop type 2 diabetes.

Metformin, vildagliptin have differing effects on heart rate, blood pressure in diabetes

Vildagliptin lowers blood pressure and elevates heart rate, while metformin increases heart rate with no effect on blood pressure.

Managing diabetic retinopathy: ADA releases new position statement

The position statement by the ADA incorporates updates in treatment and screening for patients with diabetic retinopathy.

Depression is often untreated in dialysis patients

Depression is common in patients receiving chronic hemodialysis but seems to be ineffectively treated.

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