Diabetes News Archive

ADA's 2019 Standards of Medical Care in Diabetes Focus on Patient-Centered Care

The ADA published its 2019 Standards of Medical Care in Diabetes, an evidence-based document intended to provide clinicians, patients, and other stakeholders in the diabetes treatment landscape with up-to-date recommendations.

Clinical Indicators of Risk for Addison Disease in Patients With T1D

Treatment of thyroid disease, severe infections, glucagon prescriptions, and diabetic retinopathy occur more frequently in individuals with type 1 diabetes who are subsequently diagnosed with Addison disease.

Low-Risk Patients With T2D May Be Self-Testing Blood Glucose Too Often

Patients with stable type 2 diabetes may be unnecessarily self-monitoring blood glucose levels despite this practice being recognized as a low-value service.

Skin Autofluorescence Predicts T2DM, Heart Disease, Mortality

Prediction independent of traditional risk factors such as MetS, glucose, HbA1c in general population.

Comparative Assessment of Diabetes Outcomes With Physician, NP, PA Providers

Could type of clinician rendering care influence outcomes for patients with diabetes?

Mediterranean Diet, Physical Activity Effective for Weight Loss, Decreased Cardiovascular Events

A 12-month intensive lifestyle intervention including an energy-restricted Mediterranean diet, increased physical activity, and behavioral support for overweight/obese patients was found to be beneficial in decreasing adiposity and cardiovascular events.

ACC Releases Consensus Decision Pathway for CVD Risk Reduction in T2D and ASCVD

The American College of Cardiology published an expert consensus statement regarding decision considerations for novel cardiovascular risk reduction therapies in patients with type 2 diabetes and atherosclerotic cardiovascular disease.

Several Risk Factors More Strongly Linked to MI in Women

Blood pressure, smoking, type 1 and 2 diabetes linked to higher hazard ratios for women than men.

Type 1 Diabetes Confers Extra Risk for Autoimmune Diseases

Type 1 diabetes predisposes children and adults to autoimmune diseases, which can impair glucose metabolism and interfere with insulin therapy.

Peer Support Reduces Hospitalizations in People With Diabetes and Depression

Patients with diabetes and depressive symptoms who received community-based peer support for diabetes management reported less frequent acute care visits and hospitalizations than patients with diabetes without depressive symptoms.

Food Assistance May Help Older Adults Adhere to Diabetes Medications

Food assistance may cut number of older adults with diabetes forgoing medications due to cost.

Lifestyle Intervention Program Reduces Diabetes, Metabolic Syndrome Risk

A 12-month interdisciplinary lifestyle intervention program for prediabetic and obese patients was found to significantly reduce the risk for development of diabetes and metabolic syndrome.

Early Menopause Associated With Shorter Life Expectancy, Early Diagnosis of Type 2 Diabetes

Early age of menopause development is associated with lower overall life expectancy and fewer years of life without diabetes.

ADA Issues Position Statement on Comprehensive Care for Pediatric T2D

The American Diabetes Association issued a position statement outlining the recognition, management, and prevention of T2D in the pediatric population.

CDC: About 1 in 3 Adults With Prediabetes Has Arthritis

About 1 in 3 adults with prediabetes has arthritis, and half of those with both conditions are physically inactive and/or obese.

Type 2 Diabetes May Have Adverse Effect on Parkinson Disease Symptoms, Outcomes

Patients with both Parkinson disease and type 2 diabetes were more likely to have cardiovascular comorbidities than those with only Parkinson disease.

Nonadherence, Discontinuation of Statins High in 1st Year of Prescription

Among older adults prescribed statins, diabetes, anxiety linked to nonadherence, discontinuation.

Exposure to Ready-to-Eat Food Outlets Associated With Risk for Type 2 Diabetes

Access to ready-to-eat outlets that sell food for instant consumption is associated with greater risk for type 2 diabetes.

CDC: Prevalence of Gestational Diabetes 6.0% in 2016

Based on data from 40 jurisdictions, increase from 5.2 to 5.6% in GDM from 2012 to 2016.

Plant-Based Diets Beneficial for Adults With Type 2 Diabetes

For adults with type 2 diabetes, plant-based diets can improve psychological health, quality of life, hemoglobin A1c levels.

ASN: Aggressive Control of BP, Lipids in T2DM May Up Kidney Risk

Intensive blood pressure control and fenofibrate use in patients with type 2 diabetes who are at high risk for cardiovascular disease may increase the risk for adverse kidney events.

Gastric Banding vs Metformin for Improved Insulin Sensitivity in Mild T2D

Gastric banding and metformin resulted in similar improvements in insulin sensitivity in moderately obese adults with impaired glucose tolerance or mild T2D over a 2-year period.

Biomarkers of Dairy Fat Consumption Inversely Associated With Type 2 Diabetes Risk

Researchers found that higher levels of fatty acid biomarkers 15:0, 17:0, and trans-16:1n7 were inversely associated with risk for T2D.

Glucose Dysregulation Seen Years Before Diabetes Diagnosis

Fasting plasma glucose, BMI elevated 10 years before diagnosis of prediabetes, diabetes.

Exercise After Overnight Fasting Stabilizes Glucose Levels in Type 1 Diabetes

The effect of high-intensity interval training with a bout of moderate-intensity continuous training on glucose levels was examined in T1D.

Vegan Diet Associated With Weight Loss and Reduced Insulin Resistance

Investigators examine the effect of a low-fat, plant-based diet on insulin resistance and body composition.

Empagliflozin Impact on Life Expectancy Examined in T2DM Patients With CVD

For this analysis, the authors used follow-up data from all 7020 patients included in the EMPA-REG OUTCOME trial to estimate the effect of empagliflozin on all-cause mortality vs placebo over the duration of a patient's lifetime.

ADA, EASD Issue New Recommendations for Type 2 Diabetes

Recommendations for the management of type 2 diabetes have been updated, according to a consensus report by the American Diabetes Association and the European Association for the Study of Diabetes.

Late-Onset Epilepsy Linked to APOE ε4, Smoking, Diabetes

The risk for late-onset epilepsy was lower in patients with higher physical activity levels and moderate alcohol intake.

Better Glycemic Control With Closed-Loop Insulin Delivery

Day-and-night hybrid closed-loop insulin delivery improves glucose control compared with sensor-augmented pump therapy.

Diabetes Common in Patients With Ischemic, Hemorrhagic Stroke

Approximately 28% of stroke patients have diabetes, and the presence of diabetes can increase the risk for poor stroke outcome.

Gestational Diabetes Associated With Increased Risk for Postpartum Depression

These findings suggest an increased risk for postpartum depressive symptoms in mothers with gestational diabetes, independent of depressive symptomatology during pregnancy.

CPAP for OSA Does Not Improve Diabetic Macular Edema or Visual Acuity

Continuous positive airway pressure for obstructive sleep apnea in patients with type 2 diabetes offered no improvement in visual acuity compared with usual care alone.

Combination Immunosuppressive Therapy Beneficial for Type B Insulin Resistance

A combined immunosuppressive regimen was found to be a highly effective and safe treatment for patients with type B insulin resistance.

Participation Up With Online Diabetes Prevention Program

But weight loss no different for online, in-person DPP for obese/overweight veterans with prediabetes.

Total Diabetes at 14% in US Adults for 2013-2016

Prevalence of diagnosed and undiagnosed diabetes 9.7 and 4.3%; prevalence increased with age.

Lower Hypoglycemia Risk, Greater Weight Loss With SGLT2 Inhibitor, Sulfonylurea in T2D

SGLT-2i exhibited superior effects in terms of weight loss and did not increase the risk for hypoglycemia in dual therapy with sulfonylurea.

Poor Glycemic Control Associated With Higher Risk for Dementia in Older Adults With T1D

Repeated exposure to high levels of HbA1c was associated with increased risk for dementia in a cohort of patients age ≥50 with type 1 diabetes.

Gestational Diabetes Tied to Subsequent Glucose Disorders

Long-term effects seen in mothers, but offspring not significantly overweight, obese.

Intensive Blood Pressure Therapy Lowers Cardiovascular Risk in Diabetes

Intensive blood pressure therapy is associated with a significantly lower risk for serious cardiovascular events in the adults with diabetes.

Higher Aldosterone Levels Tied to Incident Type 2 Diabetes Risk

Racial/ethnic differences seen in the association of aldosterone with incident type 2 diabetes.

T1D, Poor Glycemic Control Linked to Infection Development

Researchers found that patients with T1DM and poor glycemic control were more frequently diagnosed with infections.

Excess Cardiac Risk Varies With Age of Onset of T1D

Excess risk differed by up to 5 times across different diagnosis age groups.

FDA: Cases of Rare Gangrene of Genital Area Tied to Diabetes Drug Class

The infection developed within several months of the patients starting SGLT2 therapy and the drug was discontinued in most cases. All patients required surgery and there was 1 reported death.

Assessing the Evidence of Aspirin for Primary Prevention in Diabetes

The substantial burden of cardiovascular disease in patients with diabetes has led to the exploration of various cardiovascular disease prevention strategies, including the use of aspirin.

PedsQL 3.2 Diabetes Modules Display Excellent Measurement Ability

The PedsQL 3.2 can assist in identify new and existing therapeutic interventions for individuals with different diabetes-specific health-related quality of life profiles.

Medicaid Expansion Linked to Increase in Diabetes Prescription Fills

Fills for insulin and newer medications increased by 40 and 39%, respectively.

High Prevalence of Diabetes in Those With Severe Mental Illness

Prevalences of diabetes and prediabetes higher among racial/ethnic minorities with mental illness.

Treating Painful Diabetic Peripheral Neuropathy With Electroacupuncture

Investigators sought to determine the safety and efficacy of electroacupuncture for painful diabetic peripheral neuropathy.

Two Strategies for Preventing Diabetes in Minority Patients

Physicians can stress the factors in a patient's control and change messaging about the condition.

FDA to Review Gimoti for Diabetic Gastroparesis in Adult Women

The FDA has set a Prescription Drug User Fee Act target date of April 1, 2019.

Thyroid Dysfunction Linked to Gestational Diabetes

fT3 and fT3-to-fT4 ratio correlated positively with gestational diabetes at the first and second trimester.

Fasting Insulin vs Hemoglobin A1c: Are We Getting It Right?

The early diagnosis and management of prediabetes will have a significant impact on patient outcomes and healthcare spending.

Low-Carb Diet May Reduce HbA1c More Than Low-Fat Diet in T2D

Investigators compared low-carbohydrate with low-fat diet on glucose control and other metabolic and anthropometric variables in T2D.

Hepatic Markers Linked to Early Predictors of Type 2 Diabetes Risk in Women

Circulating hepatic markers may predict the risk for diabetes in women.

FDA Approves FreeStyle Libre 14 Day Flash Glucose Monitoring System

The new Flash Glucose Monitoring System enables patients to wear the sensor for up to 14 days compared with the existing FreeStyle Libre System that was approved for 10-day wear.

Independent Relationship Between CV Mortality, Oxidative DNA Damage in Type 2 Diabetes

This represents the prospective study confirming an independent relationship between cardiovascular mortality and oxidative DNA damage in type 2 diabetes.

Basal Insulin Analogs vs NPH Insulin to Reduce Hypoglycemia-Linked ED Visits in T2D

Compared with human neutral protamine Hagedorn insulin, basal insulin analogs do not reduce risk of hypoglycemia-linked ED visits or hospital admissions in T2D.

Diabetes Diagnosis May Impact Health Behaviors of Family

Small changes in health behaviors seen for partners of those newly diagnosed with diabetes.

NP, PA Treatment Comparable for Patients With CVD or Diabetes

Effectiveness of care and healthcare resource use for diabetes or cardiovascular disease were comparable among patients receiving care from an NP vs those managed by a PA.

Congenital Anomalies Not Linked to Metformin Use After First Trimester

Metformin use during the first trimester of pregnancy is not correlated with an increased risk of congenital anomalies.

Link Between Bullous Pemphigoid and Dipeptidyl Peptidase-4 Inhibitors

The relationship between bullous pemphigoid and dipeptidyl peptidase-4 inhibitors in type 2 diabetes.

Continuous Subcutaneous Insulin Infusion May Reduce Basal Hyperglycemia in T2D

Patients with type 2 diabetes who were initially treated with multiple daily injections were assessed before and after switching to continuous subcutaneous insulin infusion.

1996 to 2013 Saw Large Increase in Diabetes Spending

Increased spending per encounter has been the biggest driver of overall rise in spending.

Vitamin D and Gestational Hypertension, Preeclampsia Risk: Is There a Connection?

Researchers from the University of Bristol found no association between 25-hydroxyvitamin D level and pregnancy-related hypertensive disorders.

Diabetes Risk Associated With Cirrhosis, Not Chronic HCV Infection, in HIV Positive Patients

Cirrhosis is associated with an increased risk for diabetes mellitus among patients living with HIV.

Empagliflozin Reduces Risk for Nephropathy Regardless of Blood Pressure, LDL Cholesterol, HbA1c

Investigators examined renal outcomes when controlling cardiovascular risk factors, such as blood pressure, LDL-C, and HbA1c.

Risk for Below Knee Amputations With Canagliflozin vs Other Antihyperglycemic Agents

Investigators analyzed real world data to examine the risk for below-knee amputations in patients with type 2 diabetes taking canagliflozin vs other medications.

Beta-Blockers Show Varied Effects on Hypoglycemic Mortality Risk in Diabetes

Investigators examined the relationship between the use of β-blockers and incidence of hypoglycemia and risk for mortality in hospitalized patients with diabetes.

Pen vs Patch Bolus Insulin Delivery for T2D Using CGM

Investigators compared 2 methods of delivering bolus insulin, pen vs patch, using metrics from continuous glucose monitoring.

Liraglutide May Prevent Dementia in Elderly With Type 2 Diabetes

Investigators examined the efficacy of liraglutide for the prevention of dementia in elderly patients with type 2 diabetes.

Age, Baseline HbA1c May Predict Glycemic Control in Newly Diagnosed Type 2 Diabetes

Investigators examined the effectiveness of oral agents vs insulin as an initial treatment option for people newly diagnosed with type 2 diabetes.

Elevated Triglycerides, Diabetes May Be Predictors of Major Cardiovascular Events

Investigators examined cardiovascular outcomes in patients with elevated triglyceridemia and diabetes treated with statins.

Safety and Performance of Omnipod HCL for Children With Type 1 Diabetes

In children with type 1 diabetes, the Omnipod hybrid closed-loop personal model system was safe and performed well.

Type 2 Diabetes Does Not Affect Pneumonia Incidence, Outcomes After Stroke

Investigators examined the incidence and outcomes of pneumonia in patients with acute ischemic stroke and type 2 diabetes.

ITCA 650 Shows Efficacy in Reducing Weight, HbA1c in Type 2 Diabetes

The ITCA 650, a small titanium osmotic mini-pump, provides a subcutaneous infusion of exenatide over 3 or 6 months.

MEDI0382 Safe, Effective for Normalizing Glucose, Weight Loss in Type 2 Diabetes

MEDI0382 reduced body weight and normalized fasting and postprandial blood glucose levels in patients with type 2 diabetes.

Chronic Kidney Disease More Common in Type 2 Diabetes Than in Type 1 Diabetes

Investigators examined the prevalence of chronic kidney disease in adults with type 1 diabetes compared with type 2 diabetes.

Implantable Continuous Glucose Monitoring Device Safe, Effective for Adolescents

The safety assessment included incidence of insertion or procedure-related removal and device-related serious adverse events through 180 after insertion.

BCG Vaccine Tied to Reduced Hyperglycemia in Type 1 Diabetes

Systemic shift in glucose metabolism from oxidative phosphorylation to aerobic glycolysis.

Cleared Blood Glucose Monitor Systems Not Always Accurate

Six of 18 systems met predetermined accuracy standard in three of three studies

Sodium Chloride Fluid Infusion Rates Do Not Affect Pediatric Diabetic Ketoacidosis

Sodium chloride content of intravenous fluids does not affect neurologic events in children with diabetic ketoacidosis.

Long-Term Type 1 Diabetes Associated With Cognitive Decline

Deficits similar for long-term type 1 diabetes and age-matched patients with type 2 diabetes

Cancer Development Linked to Increased Diabetes Risk

Increased risk of subsequent diabetes independent of traditional diabetes risk factors

More Rapid Decline in Kidney Function for Diagnosed Diabetes

Much steeper decline in adjusted mean eGFR for those with diagnosed diabetes versus those without

Improving Insulin Access: ADA Public Policy Recommendations

The American Diabetes Association (ADA) has released a public policy statement that outlines long- and short-term recommendations for improving insulin affordability.

US Nursing Home Costs Due to Diabetes Vary Greatly by State

Per-person diabetes-attributable costs ranged from 374 in New Mexico to 1,610 in Washington, D.C.

Diabetes and Mortality: Comparing SGLT-2 Inhibitors, GLP-1 Agonists, and DPP-4 Inhibitors

For patients with type 2 diabetes, sodium-glucose cotransporter 2 inhibitors and glucagon-like peptide 1 agonists significantly reduce mortality rates compared with dipeptidyl peptidase 4 inhibitors.

Diabetes Prevalence by Type in the United States: CDC Report

The CDC conducted a study to estimate the prevalence of diagnosed diabetes among adults in 2016 by primary type.

FDA Approves AI Device to Detect Diabetic Retinopathy

Artificial intelligence software that can detect diabetic retinopathy has been approved by the U.S. Food and Drug Administration.

Eating Pecans May Cut Risk of Cardiovascular Disease, Diabetes

Benefits seen in markers of cardiometabolic disease, including insulin sensitivity

ACP supports higher HbA1c targets for pharmacotherapy in adults with T2D

ACP responds to criticism from the ADA, the Endocrine Society, the AACE, and the AADE of guidance that clinicians should aim to achieve an HbA1c level between 7% and 8% in most people with type 2 diabetes.

Early Care Transitions Beneficial for Adolescents with Type 1 Diabetes

A diabetes transition registry may help adolescents with type 1 diabetes plan and prepare for independent adult care.

Better glycemic control, weight reduction with surgical treatment for youths with T2D, severe obesity

For adolescents with type 2 diabetes and severe obesity, surgical therapy facilitates glycemic control and weight reduction better than medical therapy.

High fiber diet beneficial for gut bacteria development in type 2 diabetes

A high fiber diet promotes gut bacteria that helps blood glucose control in patients with type 2 diabetes.

New Type 2 Diabetes Guideline Recommends More Moderate HbA1c Target

The American College of Physicians has developed recommendation statements to guide clinicians in selecting targets for pharmacologic treatment of type 2 diabetes.

HbA1C levels linked to cognitive decline in diabetes

HbA1C, diabetes status, and cognitive decline during a span of 10 years were compared using data from the English Longitudinal Study of Ageing.

Standards of Medical Care in Diabetes modified for cardiovascular disease

The ADA's updates include a modified patient-focused care algorithm as well as improved risk management for CVD.

Gestational diabetes increases T2D, hypertension, heart disease risk

Women with gestational diabetes have a greater risk of developing T2D and cardiovascular events than women who were not previously diagnosed with the disease.

FDA approves shock wave device to treat diabetic foot ulcers

The FDA has approved the Dermapace System for treatment of chronic, full-thickness diabetic foot ulcers.

Sign Up for Free e-newsletters