Diabetes News Archive
The ADA published its 2019 Standards of Medical Care in Diabetes, an evidence-based document intended to provide clinicians, patients, and other stakeholders in the diabetes treatment landscape with up-to-date recommendations.
Treatment of thyroid disease, severe infections, glucagon prescriptions, and diabetic retinopathy occur more frequently in individuals with type 1 diabetes who are subsequently diagnosed with Addison disease.
Patients with stable type 2 diabetes may be unnecessarily self-monitoring blood glucose levels despite this practice being recognized as a low-value service.
Prediction independent of traditional risk factors such as MetS, glucose, HbA1c in general population.
Could type of clinician rendering care influence outcomes for patients with diabetes?
A 12-month intensive lifestyle intervention including an energy-restricted Mediterranean diet, increased physical activity, and behavioral support for overweight/obese patients was found to be beneficial in decreasing adiposity and cardiovascular events.
The American College of Cardiology published an expert consensus statement regarding decision considerations for novel cardiovascular risk reduction therapies in patients with type 2 diabetes and atherosclerotic cardiovascular disease.
Blood pressure, smoking, type 1 and 2 diabetes linked to higher hazard ratios for women than men.
Type 1 diabetes predisposes children and adults to autoimmune diseases, which can impair glucose metabolism and interfere with insulin therapy.
Patients with diabetes and depressive symptoms who received community-based peer support for diabetes management reported less frequent acute care visits and hospitalizations than patients with diabetes without depressive symptoms.
Food assistance may cut number of older adults with diabetes forgoing medications due to cost.
A 12-month interdisciplinary lifestyle intervention program for prediabetic and obese patients was found to significantly reduce the risk for development of diabetes and metabolic syndrome.
Early age of menopause development is associated with lower overall life expectancy and fewer years of life without diabetes.
The American Diabetes Association issued a position statement outlining the recognition, management, and prevention of T2D in the pediatric population.
About 1 in 3 adults with prediabetes has arthritis, and half of those with both conditions are physically inactive and/or obese.
Patients with both Parkinson disease and type 2 diabetes were more likely to have cardiovascular comorbidities than those with only Parkinson disease.
Among older adults prescribed statins, diabetes, anxiety linked to nonadherence, discontinuation.
Access to ready-to-eat outlets that sell food for instant consumption is associated with greater risk for type 2 diabetes.
Based on data from 40 jurisdictions, increase from 5.2 to 5.6% in GDM from 2012 to 2016.
For adults with type 2 diabetes, plant-based diets can improve psychological health, quality of life, hemoglobin A1c levels.
Intensive blood pressure control and fenofibrate use in patients with type 2 diabetes who are at high risk for cardiovascular disease may increase the risk for adverse kidney events.
Gastric banding and metformin resulted in similar improvements in insulin sensitivity in moderately obese adults with impaired glucose tolerance or mild T2D over a 2-year period.
Researchers found that higher levels of fatty acid biomarkers 15:0, 17:0, and trans-16:1n7 were inversely associated with risk for T2D.
Fasting plasma glucose, BMI elevated 10 years before diagnosis of prediabetes, diabetes.
The effect of high-intensity interval training with a bout of moderate-intensity continuous training on glucose levels was examined in T1D.
Investigators examine the effect of a low-fat, plant-based diet on insulin resistance and body composition.
For this analysis, the authors used follow-up data from all 7020 patients included in the EMPA-REG OUTCOME trial to estimate the effect of empagliflozin on all-cause mortality vs placebo over the duration of a patient's lifetime.
Recommendations for the management of type 2 diabetes have been updated, according to a consensus report by the American Diabetes Association and the European Association for the Study of Diabetes.
The risk for late-onset epilepsy was lower in patients with higher physical activity levels and moderate alcohol intake.
Day-and-night hybrid closed-loop insulin delivery improves glucose control compared with sensor-augmented pump therapy.
Approximately 28% of stroke patients have diabetes, and the presence of diabetes can increase the risk for poor stroke outcome.
These findings suggest an increased risk for postpartum depressive symptoms in mothers with gestational diabetes, independent of depressive symptomatology during pregnancy.
Continuous positive airway pressure for obstructive sleep apnea in patients with type 2 diabetes offered no improvement in visual acuity compared with usual care alone.
A combined immunosuppressive regimen was found to be a highly effective and safe treatment for patients with type B insulin resistance.
But weight loss no different for online, in-person DPP for obese/overweight veterans with prediabetes.
Prevalence of diagnosed and undiagnosed diabetes 9.7 and 4.3%; prevalence increased with age.
SGLT-2i exhibited superior effects in terms of weight loss and did not increase the risk for hypoglycemia in dual therapy with sulfonylurea.
Repeated exposure to high levels of HbA1c was associated with increased risk for dementia in a cohort of patients age ≥50 with type 1 diabetes.
Long-term effects seen in mothers, but offspring not significantly overweight, obese.
Intensive blood pressure therapy is associated with a significantly lower risk for serious cardiovascular events in the adults with diabetes.
Racial/ethnic differences seen in the association of aldosterone with incident type 2 diabetes.
Researchers found that patients with T1DM and poor glycemic control were more frequently diagnosed with infections.
Excess risk differed by up to 5 times across different diagnosis age groups.
The infection developed within several months of the patients starting SGLT2 therapy and the drug was discontinued in most cases. All patients required surgery and there was 1 reported death.
The substantial burden of cardiovascular disease in patients with diabetes has led to the exploration of various cardiovascular disease prevention strategies, including the use of aspirin.
The PedsQL 3.2 can assist in identify new and existing therapeutic interventions for individuals with different diabetes-specific health-related quality of life profiles.
Fills for insulin and newer medications increased by 40 and 39%, respectively.
Prevalences of diabetes and prediabetes higher among racial/ethnic minorities with mental illness.
Investigators sought to determine the safety and efficacy of electroacupuncture for painful diabetic peripheral neuropathy.
Physicians can stress the factors in a patient's control and change messaging about the condition.
The FDA has set a Prescription Drug User Fee Act target date of April 1, 2019.
fT3 and fT3-to-fT4 ratio correlated positively with gestational diabetes at the first and second trimester.
The early diagnosis and management of prediabetes will have a significant impact on patient outcomes and healthcare spending.
Investigators compared low-carbohydrate with low-fat diet on glucose control and other metabolic and anthropometric variables in T2D.
Circulating hepatic markers may predict the risk for diabetes in women.
The new Flash Glucose Monitoring System enables patients to wear the sensor for up to 14 days compared with the existing FreeStyle Libre System that was approved for 10-day wear.
This represents the prospective study confirming an independent relationship between cardiovascular mortality and oxidative DNA damage in type 2 diabetes.
Compared with human neutral protamine Hagedorn insulin, basal insulin analogs do not reduce risk of hypoglycemia-linked ED visits or hospital admissions in T2D.
Small changes in health behaviors seen for partners of those newly diagnosed with diabetes.
Effectiveness of care and healthcare resource use for diabetes or cardiovascular disease were comparable among patients receiving care from an NP vs those managed by a PA.
Metformin use during the first trimester of pregnancy is not correlated with an increased risk of congenital anomalies.
The relationship between bullous pemphigoid and dipeptidyl peptidase-4 inhibitors in type 2 diabetes.
Patients with type 2 diabetes who were initially treated with multiple daily injections were assessed before and after switching to continuous subcutaneous insulin infusion.
Increased spending per encounter has been the biggest driver of overall rise in spending.
Researchers from the University of Bristol found no association between 25-hydroxyvitamin D level and pregnancy-related hypertensive disorders.
Cirrhosis is associated with an increased risk for diabetes mellitus among patients living with HIV.
Investigators examined renal outcomes when controlling cardiovascular risk factors, such as blood pressure, LDL-C, and HbA1c.
Investigators analyzed real world data to examine the risk for below-knee amputations in patients with type 2 diabetes taking canagliflozin vs other medications.
Investigators examined the relationship between the use of β-blockers and incidence of hypoglycemia and risk for mortality in hospitalized patients with diabetes.
Investigators compared 2 methods of delivering bolus insulin, pen vs patch, using metrics from continuous glucose monitoring.
Investigators examined the efficacy of liraglutide for the prevention of dementia in elderly patients with type 2 diabetes.
Investigators examined the effectiveness of oral agents vs insulin as an initial treatment option for people newly diagnosed with type 2 diabetes.
Investigators examined cardiovascular outcomes in patients with elevated triglyceridemia and diabetes treated with statins.
In children with type 1 diabetes, the Omnipod hybrid closed-loop personal model system was safe and performed well.
Investigators examined the incidence and outcomes of pneumonia in patients with acute ischemic stroke and type 2 diabetes.
The ITCA 650, a small titanium osmotic mini-pump, provides a subcutaneous infusion of exenatide over 3 or 6 months.
MEDI0382 reduced body weight and normalized fasting and postprandial blood glucose levels in patients with type 2 diabetes.
Investigators examined the prevalence of chronic kidney disease in adults with type 1 diabetes compared with type 2 diabetes.
The safety assessment included incidence of insertion or procedure-related removal and device-related serious adverse events through 180 after insertion.
Systemic shift in glucose metabolism from oxidative phosphorylation to aerobic glycolysis.
Six of 18 systems met predetermined accuracy standard in three of three studies
Sodium chloride content of intravenous fluids does not affect neurologic events in children with diabetic ketoacidosis.
Deficits similar for long-term type 1 diabetes and age-matched patients with type 2 diabetes
Increased risk of subsequent diabetes independent of traditional diabetes risk factors
Much steeper decline in adjusted mean eGFR for those with diagnosed diabetes versus those without
The American Diabetes Association (ADA) has released a public policy statement that outlines long- and short-term recommendations for improving insulin affordability.
Per-person diabetes-attributable costs ranged from 374 in New Mexico to 1,610 in Washington, D.C.
For patients with type 2 diabetes, sodium-glucose cotransporter 2 inhibitors and glucagon-like peptide 1 agonists significantly reduce mortality rates compared with dipeptidyl peptidase 4 inhibitors.
The CDC conducted a study to estimate the prevalence of diagnosed diabetes among adults in 2016 by primary type.
Artificial intelligence software that can detect diabetic retinopathy has been approved by the U.S. Food and Drug Administration.
Benefits seen in markers of cardiometabolic disease, including insulin sensitivity
ACP responds to criticism from the ADA, the Endocrine Society, the AACE, and the AADE of guidance that clinicians should aim to achieve an HbA1c level between 7% and 8% in most people with type 2 diabetes.
A diabetes transition registry may help adolescents with type 1 diabetes plan and prepare for independent adult care.
Better glycemic control, weight reduction with surgical treatment for youths with T2D, severe obesity
For adolescents with type 2 diabetes and severe obesity, surgical therapy facilitates glycemic control and weight reduction better than medical therapy.
A high fiber diet promotes gut bacteria that helps blood glucose control in patients with type 2 diabetes.
The American College of Physicians has developed recommendation statements to guide clinicians in selecting targets for pharmacologic treatment of type 2 diabetes.
HbA1C, diabetes status, and cognitive decline during a span of 10 years were compared using data from the English Longitudinal Study of Ageing.
The ADA's updates include a modified patient-focused care algorithm as well as improved risk management for CVD.
Women with gestational diabetes have a greater risk of developing T2D and cardiovascular events than women who were not previously diagnosed with the disease.
The FDA has approved the Dermapace System for treatment of chronic, full-thickness diabetic foot ulcers.