A great deal of progress has been made in reducing the burden of diarrheal diseases, but this reduction has not been equal globally.
The test works by measuring levels of anti-cytolethal distending toxin B (CdtB) and anti-vinculin, 2 biomarkers of post-infectious IBS-D and IBS-M.
A 2-week course of treatment with rifaximin for diarrhea-predominant irritable bowel syndrome was found to improve abdominal pain symptoms.
The first step for managing a patient with diarrhea is to determine the severity of dehydration according to the estimated volume loss and the symptoms and signs noted on physical examination.
A 60-year-old man with a history of gastroesophageal reflux disease presents to the emergency department with 2 to 3 days of fever, non-bloody diarrhea, and a worsening non-pruritic rash.
Supplements have no clear effect on mortality and a slight effect on promoting children's growth.
Probiotic supplements do not appear to prevent antibiotic-associated diarrhea (AAD) or diarrhea caused by Clostridium difficile in elderly patients.
For patient's with chemotherapy induced diarrhea, try alternating between these two medications before moving on to something stronger.
What are the next steps after ruling out Clostridium difficile?
The majority of patients with recurrent Clostridium difficile-associated infection recover after undergoing fecal transplantation via colonoscopy.
Post-licensure data from the Vaccine Safety Datalink did not show increases in intussusception among infants aged 4 to 34 weeks in the first week or month after vaccination with the pentavalent rotavirus vaccine.
Advise patients who experience watery stool that does not go away, abdominal pain and fever while taking PPIs to seek medical attention immediately.
Norovirus outbreaks predominated in behavioral health and rehabilitation/long-term care facilities, whereas bacterial infections were more likely to occur in medical and surgical units.
Advising patients to take OTC antidiarrheal medications at specific times in relation to when they eat their meals can help reduce the number of bowel movements.
Fidaxomicin was noninferior to vancomycin among adults with Clostridium difficile-associated diarrhea in two randomized, double blind trials.
Local injections to narrow the anal canal reduced fecal incontinence by 25% at one-year follow-up, data from recent clinical trials indicate.