Hyperacidity, GERD, and ulcers:

Indications for Nizatidine Oral Solution:

Active duodenal ulcer. Maintenance of healed duodenal ulcer. Benign gastric ulcer. Gastroesophageal reflux disease (GERD): including heartburn and erosive and ulcerative esophagitis.

Adult:

Active duodenal or benign gastric ulcer: 300mg daily at bedtime or 150mg twice daily, both for up to 8 weeks. Maintenance: 150mg daily at bedtime. GERD: 150mg twice daily for up to 12 weeks. Renal impairment (CrCl ≤50mL/min): reduce dose (see full labeling).

Children:

<12yrs: not established. Use oral soln. Erosive esophagitis, GERD (≥12yrs): 150mg twice daily for up to 8 weeks; max 300mg/day. Renal impairment (CrCl ≤50mL/min): reduce dose (see full labeling).

Warnings/Precautions:

Rule out malignant gastric ulceration. Renal impairment. Elderly. Pregnancy (Cat.B). Nursing mothers: not recommended.

Pharmacologic Class:

H2 blocker.

Interactions:

May elevate serum salicylate levels in high-dose aspirin patients.

Adverse Reactions:

Headache, anemia, diarrhea, dizziness, sweating, rhinitis, urticaria.

Note:

Formerly known under the brand name Axid.

How Supplied:

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