Indications for: Benztropine Injection

Adjunct in Parkinsonism, drug-induced extrapyramidal disorders.

Adult Dosage:

Parkinsonism: initially 0.5–1mg at bedtime. May increase by 0.5mg at 5–6 day intervals; max 6mg daily. Extrapyramidal disorders: 1–4mg 1–2 times daily. Acute dystonic reactions: 1–2mg IM or IV.

Children Dosage:

See Contraindications. Use cautiously in older children.

Benztropine Injection Contraindications:

Children <3yrs old.

Benztropine Injection Warnings/Precautions:

Tardive dyskinesia: not recommended. Narrow-angle glaucoma. Tachycardia. Psychosis. Prostatic hypertrophy. GI or GU obstruction. Chronically ill. Alcoholics. CNS disease. Exposure to extreme heat. Elderly. Pregnancy.

See Also:

Benztropine Injection Classification:


Benztropine Injection Interactions:

Paralytic ileus, hyperthermia, heat stroke with phenothiazines, tricyclic antidepressants. Antagonizes psychotropics.

Adverse Reactions:

Anticholinergic and antihistaminic effects, weakness, confusion, anhidrosis, excitement, GI upset, depression, lethargy, heat stroke, dysuria, toxic psychosis, rash.


Formerly known under the brand name Cogentin.


N-oxidation, N-dealkylation, ring hydroxylation. ~95% serum protein bound.

Drug Elimination:

Renal. Half-life: ~36 hours.

How Supplied:

Contact supplier