Hypertension:
Indications for: Labetalol HCl Tablets
Hypertension.
Adult Dosage:
Individualize. Initially 100mg twice daily. Titrate at 2–3 day intervals in increments of 100mg twice daily. Usual maintenance: 200–400mg twice daily; max 2.4g/day.
Children Dosage:
Not recommended.
Labetalol HCl Tablets Contraindications:
Asthma. 2nd- or 3rd-degree AV block. Overt cardiac failure. Cardiogenic shock. Severe bradycardia, other conditions associated with prolonged or severe hypotension.
Labetalol HCl Tablets Warnings/Precautions:
History of heart failure; withdraw gradually if cardiac failure continues despite adequate digitalization and diuretic. Monitor hepatic function; discontinue at first sign of liver injury. COPD. Pheochromocytoma. Diabetes. Surgery. Avoid abrupt cessation (ischemic heart disease may be exacerbated). Elderly. Pregnancy (Cat.C). Nursing mothers.
Labetalol HCl Tablets Classification:
Noncardioselective beta-blocker/alpha-1 blocker.
Labetalol HCl Tablets Interactions:
Caution with verapamil. Potentiates hypotension with nitroglycerin. May block epinephrine, β-agonist bronchodilators. Adjust antidiabetic medication. Potentiated by cimetidine. Tremor with tricyclic antidepressants. Synergism with halothane; do not use high concentrations.
Adverse Reactions:
Dizziness, GI upset, fatigue, nasal stuffiness, ejaculation failure, headache, dyspnea, vertigo, rash, orthostatic hypotension, edema, heart failure, bronchospasm, jaundice.
Note:
Formerly known under the brand names Normodyne, Trandate.
How Supplied:
Contact supplier.
