Urine acidification/alkalinization:

Indications for UROCIT-K:

Renal tubular acidosis with calcium stones. Hypocitraturic calcium oxalate nephrolithiasis. Uric acid lithiasis.


Take within 30 minutes of meals or bedtime snack. Adjust based on urinary citrate levels and/or pH. Urinary citrate <150mg/day: 30mEq twice daily or 20mEq 3 times daily. Urinary citrate >150mEq/day: 15mEq twice daily or 10mEq 3 times daily. Max 100mEq/day.


Not recommended.


See literature. Hyperkalemia or predisposing conditions. GI narrowing or stricture, delayed gastric emptying or predisposing conditions. Peptic ulcer disease. UTI. Renal insufficiency (GFR <0.7mL/kg per minute).


Restrict salt intake and encourage high fluid intake. Discontinue if severe vomiting, GI pain or bleeding occurs and follow-up. Monitor 24 hour urinary citrate, urinary pH, serum electrolytes, CBC, ECG, at least every 4 months; discontinue if hyperkalemia, significant rise in serum creatinine, or significant fall in hematocrit or hemoglobin occurs. Pregnancy (Cat.C). Nursing mothers.

Pharmacologic Class:

Urinary alkalinizer.


Contraindicated with potassium-sparing diuretics, anticholinergics, other drugs that slow GI motility. Monitor digoxin. May interfere with some urinary tract antibiotics. Caution with drugs that raise serum potassium.

Adverse Reactions:

Hyperkalemia, GI upset, irritation, bleeding.

How Supplied:


Pricing for UROCIT-K

10meq tablet (Qty: 180)
Appx. price $99