Endocrinology News Archive
Increasing screen trends may have negative cardiometabolic impact; panel calls for more research.
The insulin sensitivity in post- and premenopausal women along with lipid deposition in the liver and skeletal muscle was examined.
Investigators compared low-carbohydrate with low-fat diet on glucose control and other metabolic and anthropometric variables in T2D.
Circulating hepatic markers may predict the risk for diabetes in women.
The new Flash Glucose Monitoring System enables patients to wear the sensor for up to 14 days compared with the existing FreeStyle Libre System that was approved for 10-day wear.
This represents the prospective study confirming an independent relationship between cardiovascular mortality and oxidative DNA damage in type 2 diabetes.
Childhood obesity continues to be a public health issue that requires improved policies and interventions at both the individual and population level.
Investigators examined the effect of consuming a Mediterranean-style diet for 1 year on inflammatory response and bone health in the elderly.
Compared with human neutral protamine Hagedorn insulin, basal insulin analogs do not reduce risk of hypoglycemia-linked ED visits or hospital admissions in T2D.
Small changes in health behaviors seen for partners of those newly diagnosed with diabetes.
Effectiveness of care and healthcare resource use for diabetes or cardiovascular disease were comparable among patients receiving care from an NP vs those managed by a PA.
The relationship between bullous pemphigoid and dipeptidyl peptidase-4 inhibitors in type 2 diabetes.
No differences seen with other fat volume measures between recurring, first-time stones.
This retrospective study sought to assess migraine patterns in 69 menopausal women between ages 40 and 60 who were treated at Partners Healthcare Hospitals for concurrent migraine headache.
Women prescribed long- vs short-term opioids for chronic musculoskeletal pain may be at increased risk for menopause and abnormal menstruation.
Patients with type 2 diabetes who were initially treated with multiple daily injections were assessed before and after switching to continuous subcutaneous insulin infusion.
Increased spending per encounter has been the biggest driver of overall rise in spending.
Policy supports evidence-based strategies such as excise taxes, adding warning labels
Cirrhosis is associated with an increased risk for diabetes mellitus among patients living with HIV.
Increased weight loss with risk factor management associated with greater atrial fibrillation freedom.
Investigators examined renal outcomes when controlling cardiovascular risk factors, such as blood pressure, LDL-C, and HbA1c.
Hormone therapy in postmenopausal women with mild cognitive impairment was examined.
Investigators analyzed real world data to examine the risk for below-knee amputations in patients with type 2 diabetes taking canagliflozin vs other medications.
Investigators examined the relationship between the use of β-blockers and incidence of hypoglycemia and risk for mortality in hospitalized patients with diabetes.
Investigators compared 2 methods of delivering bolus insulin, pen vs patch, using metrics from continuous glucose monitoring.
Researchers assessed whether current metabolic parameters are inversely associated with cognitive functioning.
Investigators examined the efficacy of liraglutide for the prevention of dementia in elderly patients with type 2 diabetes.
Investigators examined the effectiveness of oral agents vs insulin as an initial treatment option for people newly diagnosed with type 2 diabetes.
Investigators examined cardiovascular outcomes in patients with elevated triglyceridemia and diabetes treated with statins.
In children with type 1 diabetes, the Omnipod hybrid closed-loop personal model system was safe and performed well.
Investigators examined the incidence and outcomes of pneumonia in patients with acute ischemic stroke and type 2 diabetes.
The ITCA 650, a small titanium osmotic mini-pump, provides a subcutaneous infusion of exenatide over 3 or 6 months.
MEDI0382 reduced body weight and normalized fasting and postprandial blood glucose levels in patients with type 2 diabetes.
Investigators examined the prevalence of chronic kidney disease in adults with type 1 diabetes compared with type 2 diabetes.
The safety assessment included incidence of insertion or procedure-related removal and device-related serious adverse events through 180 after insertion.
Screening with bone measurement recommended for women aged 65, younger women at risk
Postmenopausal women have little awareness of osteoporotic fracture risk and poor understanding that a fragility fracture may be indicative of osteoporosis and that it increases future fracture risk.
Systemic shift in glucose metabolism from oxidative phosphorylation to aerobic glycolysis.
Six of 18 systems met predetermined accuracy standard in three of three studies
Sodium chloride content of intravenous fluids does not affect neurologic events in children with diabetic ketoacidosis.
Fetal genetic score for birth weight affects fetal growth at various maternal fasting plasma glucose levels.
No Additional Benefits With Vaginal Estradiol Tablets, Moisturizers for Postmenopausal Vulvovaginal Symptoms
Prescribed vaginal estradiol tablets and over-the-counter vaginal moisturizers may not be more effective than placebos for postmenopausal vulvovaginal symptoms.
Deficits similar for long-term type 1 diabetes and age-matched patients with type 2 diabetes
Increased risk of subsequent diabetes independent of traditional diabetes risk factors
If trends continue, about one-third of children and one-half of teens will be obese/overweight by 2030.
Equol-containing nutraceuticals may be beneficial for postmenopausal women with vaginal symptoms.
Much steeper decline in adjusted mean eGFR for those with diagnosed diabetes versus those without
The FDA approval was supported by findings from a Phase 3, randomized, double-blind, placebo-controlled study that evaluated Imvexxy (4mcg and 10mcg) vs placebo from baseline to week 12.
Age at diagnosis, sex, BMI, and thyroid-stimulating hormone suppression therapy affect CVD risk
The American Diabetes Association (ADA) has released a public policy statement that outlines long- and short-term recommendations for improving insulin affordability.
The new program, announced by AAPA, will allow its participants to obtain 30 CME credits and an OMA-issued Certificate of Primary-Care Obesity Management after completion.
Recognizing the obesity epidemic and educating physician assistants on the implications of this condition and how they should be caring for obese patients should be prioritized, according to the study authors.
Per-person diabetes-attributable costs ranged from 374 in New Mexico to 1,610 in Washington, D.C.
The study authors examined data obtained from the 2007-2008 National Survey of Children's Health (NSCH) to determine the prevalence, risk factors, as well as the severity of asthma phenotypes.
Artificial pancreas treatments are safe and effective for managing type 1 diabetes.
For patients with type 2 diabetes, sodium-glucose cotransporter 2 inhibitors and glucagon-like peptide 1 agonists significantly reduce mortality rates compared with dipeptidyl peptidase 4 inhibitors.
The CDC conducted a study to estimate the prevalence of diagnosed diabetes among adults in 2016 by primary type.
Artificial intelligence software that can detect diabetic retinopathy has been approved by the U.S. Food and Drug Administration.
Benefits seen in markers of cardiometabolic disease, including insulin sensitivity
Increased adiposity in childhood may negatively impact liver function in children as young as 8 years old.
The two most prevalent HIV symptoms, fatigue and muscle aches, are more common in women than men and can worsen with menopause.
BMI is positively correlated with increased hepatocellular carcinoma in patients with chronic HBV, though the risk is greater in women.
A diabetes transition registry may help adolescents with type 1 diabetes plan and prepare for independent adult care.
Better glycemic control, weight reduction with surgical treatment for youths with T2D, severe obesity
For adolescents with type 2 diabetes and severe obesity, surgical therapy facilitates glycemic control and weight reduction better than medical therapy.
The American College of Physicians has developed recommendation statements to guide clinicians in selecting targets for pharmacologic treatment of type 2 diabetes.
Obesity is affiliated with elevated morbidity, cardiovascular disease related mortality, and shorter longevity compared with individuals with a normal body mass index.
Bacterial vaginosis may cause an increased risk for HIV acquisition in women taking oral or injectable hormonal contraception.
HbA1C, diabetes status, and cognitive decline during a span of 10 years were compared using data from the English Longitudinal Study of Ageing.
The ADA's updates include a modified patient-focused care algorithm as well as improved risk management for CVD.
Weight loss in obese individuals may lead to reduced pain, affect, and somatic symptoms associated with chronic pain.
Severe obesity may decline in children enrolled in specialized diet programs.
The investigators studied the association between abdominal fat, inflammation, and fitness by measuring body weight, dimensions, and blood samples.
A positive correlation between increased BMI and risk of prostate cancer recurrence was observed in patients undergoing radical prostatectomy.
Some of the comorbidities include increased lipid levels, hypertension, and diabetes.
There is no statistically significant difference in weight loss at 5 years after laparoscopic sleeve gastrectomy vs laparoscopic Roux-en-Y gastric bypass in morbidly obese patients.
The FDA has approved the Dermapace System for treatment of chronic, full-thickness diabetic foot ulcers.
More than 40 diet plans across 9 categories have been ranked to help those dieting achieve healthier lifestyles in U.S News & World Report.
Overweight/obese preschools have greater asthma symptoms than normal-weight children when untreated.
Findings do not support routine vitamin D and calcium supplementation in community-dwelling older adults for lowering the incidence of osteoporosis-related fractures.
The new FDA approved short-acting insulin drug can be used to treat T1 and T2 diabetes.
Body mass index BMI at a cut-point of 30 kg/m2 may not be an appropriate indicator of obesity in postmenopausal women.
Cocoa, dark chocolate, and raw almonds may help improve lipid profiles in overweight individuals.
Adult obesity by age of 35 is likely in about 57% of today's children.
The USPSTF has updated its recommendations on the use of menopausal hormone therapy for the primary prevention of chronic conditions.
The FDA has approved semaglutide injection as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
Oral insulin usage does not prevent the development of type 1 diabetes in relatives of patients.
Weight-loss diets low in fat and saturated fat consumption, with or without added exercise, may reduce the risk for all-cause mortality in obese adults.
The USPSTF has updated its recommendations on osteoporosis screening and testing in women and men.
Incidence rates of overweight- and obesity-related cancers have increased in the United States.
Early menopause risk is highest in weight-cycling and severely underweight women.
Primary care referral to Weight Watchers meetings is associated with weight loss, HbA1c reduction.
The meta-analysis showed that short-term probiotic supplementation reduced body weight, BMI, and fat percentage, but the effect sizes were small.
Statins are associated with an increased risk for developing type 2 diabetes, especially for high-risk individuals.
With a little creativity, children with diabetes can enjoy the festivities of Halloween.
Among women who are attempting to conceive naturally, diminished ovarian reserve is not associated with infertility.
Type 2 diabetes risk is increased in young adults through antidepressant use, specifically the duration of use and the cumulative dose.
CBGT did not prevent overweight and obese patients with type 2 diabetes from regaining weight lost during weight loss programs.
Type 2 diabetes is greater with second-generation antipsychotics than with non-second-generation antipsychotic psychotropic medications for patients aged 6 to 25 years.
The AAP Section for Endocrinology compiled the list of tests for height and puberty, which should prompt careful discussion between parents and physicians.
Insulin pump therapy is linked to lower risks of severe hypoglycemia and diabetic ketoacidosis and better glycemic control than insulin injection therapy.