Endocrinology News Archive
The risk for late-onset epilepsy was lower in patients with higher physical activity levels and moderate alcohol intake.
Day-and-night hybrid closed-loop insulin delivery improves glucose control compared with sensor-augmented pump therapy.
Approximately 28% of stroke patients have diabetes, and the presence of diabetes can increase the risk for poor stroke outcome.
Women with ovarian or endometrial cancer who adhere to a ketogenic diet may benefit from a selective loss of fat mass and a reduction in fasting serum insulin, while still retaining lean mass.
Hypertensive disorders of pregnancy and gestational diabetes may increase the risk for hot flashes during menopause.
Light treatments successfully corrected abnormal timing of melatonin circadian rhythms in perimenopausal women with depression and improved mood and sleep within 2 weeks.
The upper level of vitamin D recommended by the Endocrine Society can result in frequent hypercalciuria.
Continuous positive airway pressure for obstructive sleep apnea in patients with type 2 diabetes offered no improvement in visual acuity compared with usual care alone.
A combined immunosuppressive regimen was found to be a highly effective and safe treatment for patients with type B insulin resistance.
Increased weight loss vs placebo with no rise in rate of extended major cardiovascular events.
But weight loss no different for online, in-person DPP for obese/overweight veterans with prediabetes.
Prevalence of diagnosed and undiagnosed diabetes 9.7 and 4.3%; prevalence increased with age.
SGLT-2i exhibited superior effects in terms of weight loss and did not increase the risk for hypoglycemia in dual therapy with sulfonylurea.
Findings among diverse population of overweight, obese women.
Researchers concluded that physical activity was not associated with risk for early menopause.
Repeated exposure to high levels of HbA1c was associated with increased risk for dementia in a cohort of patients age ≥50 with type 1 diabetes.
Intensive blood pressure therapy is associated with a significantly lower risk for serious cardiovascular events in the adults with diabetes.
Racial/ethnic differences seen in the association of aldosterone with incident type 2 diabetes.
The USPSTF recommends that clinicians refer adults with a body mass index of 30 or higher to intensive, multicompetent behavioral interventions.
According to the Imvexxy prescribing information, women should generally be started at the 4mcg dosage strength with dosage adjustment guided by clinical response.
The 5 topics addressed by the 11-member expert panel include epidemiology, clinical presentation, therapeutic effects of antidepressants, effects of hormone therapy, and the effectiveness of other therapies (eg, psychotherapy, exercise, natural health products).
Researchers found that patients with T1DM and poor glycemic control were more frequently diagnosed with infections.
Excess risk differed by up to 5 times across different diagnosis age groups.
The substantial burden of cardiovascular disease in patients with diabetes has led to the exploration of various cardiovascular disease prevention strategies, including the use of aspirin.
Investigators assessed whether adrenal suppression with low-dose dexamethasone improved IVF outcomes.
The PedsQL 3.2 can assist in identify new and existing therapeutic interventions for individuals with different diabetes-specific health-related quality of life profiles.
Experts in the management of acromegaly provide new recommendations on the medical management of acromegaly since the last published update in 2014.
Obese women have significantly higher bacterial biomass of lower diversity at the incision site.
Compared with uninfected individuals, people with HIV controlled with combination antiretroviral therapy are not at increased risk of developing thyroid dysfunction.
Fills for insulin and newer medications increased by 40 and 39%, respectively.
Stroke risk 19% lower with breastfeeding for 1 to 6 months; stronger link for longer duration.
Prevalences of diabetes and prediabetes higher among racial/ethnic minorities with mental illness.
The International Society for the Study of Women's Sexual Health convened an expert consensus panel to discuss the use of androgens in the management of genitourinary syndrome of menopause.
Investigators sought to determine the safety and efficacy of electroacupuncture for painful diabetic peripheral neuropathy.
Physicians can stress the factors in a patient's control and change messaging about the condition.
The FDA has set a Prescription Drug User Fee Act target date of April 1, 2019.
Investigators examined the relationship between menstrual cycle characteristics in adolescence and early adulthood and the risk for early natural menopause.
There are 14 states that perform a routine second screening in infants at approximately 2 weeks of age.
American Heart Association science advisory recommends healthy eating patterns instead.
No Impact on Carotid Artery Intima-Media Thickness Following Cessation of Menopausal Hormone Therapy
A follow-up study from KEEPS found that cessation of menopausal hormone therapy did not change the expected trajectory of carotid artery intima-media thickness over a 3-year period.
It is critical for us to remember that children are not little adults. Pediatric-onset diabetes is different from adult-onset diabetes due to its distinct epidemiology, pathophysiology, developmental considerations, and response to therapy.
Increasing screen trends may have negative cardiometabolic impact; panel calls for more research.
The insulin sensitivity in post- and premenopausal women along with lipid deposition in the liver and skeletal muscle was examined.
Investigators compared low-carbohydrate with low-fat diet on glucose control and other metabolic and anthropometric variables in T2D.
Circulating hepatic markers may predict the risk for diabetes in women.
The new Flash Glucose Monitoring System enables patients to wear the sensor for up to 14 days compared with the existing FreeStyle Libre System that was approved for 10-day wear.
This represents the prospective study confirming an independent relationship between cardiovascular mortality and oxidative DNA damage in type 2 diabetes.
Childhood obesity continues to be a public health issue that requires improved policies and interventions at both the individual and population level.
Investigators examined the effect of consuming a Mediterranean-style diet for 1 year on inflammatory response and bone health in the elderly.
Compared with human neutral protamine Hagedorn insulin, basal insulin analogs do not reduce risk of hypoglycemia-linked ED visits or hospital admissions in T2D.
Small changes in health behaviors seen for partners of those newly diagnosed with diabetes.
Effectiveness of care and healthcare resource use for diabetes or cardiovascular disease were comparable among patients receiving care from an NP vs those managed by a PA.
The relationship between bullous pemphigoid and dipeptidyl peptidase-4 inhibitors in type 2 diabetes.
No differences seen with other fat volume measures between recurring, first-time stones.
This retrospective study sought to assess migraine patterns in 69 menopausal women between ages 40 and 60 who were treated at Partners Healthcare Hospitals for concurrent migraine headache.
Women prescribed long- vs short-term opioids for chronic musculoskeletal pain may be at increased risk for menopause and abnormal menstruation.
Patients with type 2 diabetes who were initially treated with multiple daily injections were assessed before and after switching to continuous subcutaneous insulin infusion.
Increased spending per encounter has been the biggest driver of overall rise in spending.
Policy supports evidence-based strategies such as excise taxes, adding warning labels
Cirrhosis is associated with an increased risk for diabetes mellitus among patients living with HIV.
Increased weight loss with risk factor management associated with greater atrial fibrillation freedom.
Investigators examined renal outcomes when controlling cardiovascular risk factors, such as blood pressure, LDL-C, and HbA1c.
Hormone therapy in postmenopausal women with mild cognitive impairment was examined.
Investigators analyzed real world data to examine the risk for below-knee amputations in patients with type 2 diabetes taking canagliflozin vs other medications.
Investigators examined the relationship between the use of β-blockers and incidence of hypoglycemia and risk for mortality in hospitalized patients with diabetes.
Investigators compared 2 methods of delivering bolus insulin, pen vs patch, using metrics from continuous glucose monitoring.
Researchers assessed whether current metabolic parameters are inversely associated with cognitive functioning.
Investigators examined the efficacy of liraglutide for the prevention of dementia in elderly patients with type 2 diabetes.
Investigators examined the effectiveness of oral agents vs insulin as an initial treatment option for people newly diagnosed with type 2 diabetes.
Investigators examined cardiovascular outcomes in patients with elevated triglyceridemia and diabetes treated with statins.
In children with type 1 diabetes, the Omnipod hybrid closed-loop personal model system was safe and performed well.
Investigators examined the incidence and outcomes of pneumonia in patients with acute ischemic stroke and type 2 diabetes.
The ITCA 650, a small titanium osmotic mini-pump, provides a subcutaneous infusion of exenatide over 3 or 6 months.
MEDI0382 reduced body weight and normalized fasting and postprandial blood glucose levels in patients with type 2 diabetes.
Investigators examined the prevalence of chronic kidney disease in adults with type 1 diabetes compared with type 2 diabetes.
The safety assessment included incidence of insertion or procedure-related removal and device-related serious adverse events through 180 after insertion.
Screening with bone measurement recommended for women aged 65, younger women at risk
Postmenopausal women have little awareness of osteoporotic fracture risk and poor understanding that a fragility fracture may be indicative of osteoporosis and that it increases future fracture risk.
Systemic shift in glucose metabolism from oxidative phosphorylation to aerobic glycolysis.
Six of 18 systems met predetermined accuracy standard in three of three studies
Sodium chloride content of intravenous fluids does not affect neurologic events in children with diabetic ketoacidosis.
Fetal genetic score for birth weight affects fetal growth at various maternal fasting plasma glucose levels.
No Additional Benefits With Vaginal Estradiol Tablets, Moisturizers for Postmenopausal Vulvovaginal Symptoms
Prescribed vaginal estradiol tablets and over-the-counter vaginal moisturizers may not be more effective than placebos for postmenopausal vulvovaginal symptoms.
Deficits similar for long-term type 1 diabetes and age-matched patients with type 2 diabetes
Increased risk of subsequent diabetes independent of traditional diabetes risk factors
If trends continue, about one-third of children and one-half of teens will be obese/overweight by 2030.
Equol-containing nutraceuticals may be beneficial for postmenopausal women with vaginal symptoms.
Much steeper decline in adjusted mean eGFR for those with diagnosed diabetes versus those without
The FDA approval was supported by findings from a Phase 3, randomized, double-blind, placebo-controlled study that evaluated Imvexxy (4mcg and 10mcg) vs placebo from baseline to week 12.
Age at diagnosis, sex, BMI, and thyroid-stimulating hormone suppression therapy affect CVD risk
The American Diabetes Association (ADA) has released a public policy statement that outlines long- and short-term recommendations for improving insulin affordability.
The new program, announced by AAPA, will allow its participants to obtain 30 CME credits and an OMA-issued Certificate of Primary-Care Obesity Management after completion.
Recognizing the obesity epidemic and educating physician assistants on the implications of this condition and how they should be caring for obese patients should be prioritized, according to the study authors.
Per-person diabetes-attributable costs ranged from 374 in New Mexico to 1,610 in Washington, D.C.
The study authors examined data obtained from the 2007-2008 National Survey of Children's Health (NSCH) to determine the prevalence, risk factors, as well as the severity of asthma phenotypes.
Artificial pancreas treatments are safe and effective for managing type 1 diabetes.
For patients with type 2 diabetes, sodium-glucose cotransporter 2 inhibitors and glucagon-like peptide 1 agonists significantly reduce mortality rates compared with dipeptidyl peptidase 4 inhibitors.
The CDC conducted a study to estimate the prevalence of diagnosed diabetes among adults in 2016 by primary type.
Artificial intelligence software that can detect diabetic retinopathy has been approved by the U.S. Food and Drug Administration.
Benefits seen in markers of cardiometabolic disease, including insulin sensitivity