The comorbid presence of central apnea has been identified by multiple researchers as predictive of SUDEP.
Researchers examined a database of seizure-related deaths to determine whether cause was drowning or sudden unexpected death in epilepsy.
Those with a low risk for SUDEP generally remain in this categorization during 3 years of tracking.
Crude mortality rates for individuals with dementia were 5 times higher than for those without.
Safety data for Fycompa was consistent with the safety profile in adult populations without the need for weight-based dosing.
The Company states that the NDA is supported by robust clinical trial data, including patients studies where more than 1600 seizures were treated with Valtoco nasal spray.
Recurrence of seizures was reported in 28.2% of patients who attempted withdrawal.
The risk for late-onset epilepsy was lower in patients with higher physical activity levels and moderate alcohol intake.
The odds of language delay were lower at 18 months and 36 months in children exposed to AEDs in utero whose mothers took folic acid.
Although 2 patients experienced an increase in seizure frequency, the remaining patients did not experience a change in frequency.
An expert subcommittee was formed consisting of members of the AAN and AES to update the 2004 evidence-based guidelines on epilepsy treatment with AEDs.
Causes of death in patients with epilepsy were assessed to determine the presence of cardiac pathology.
Patients with epilepsy have a greater risk of unnatural mortality than individuals without the disorder and should take greater precautions when taking certain medications.
In Utero Exposure to Multiple AEDs, Sodium Valproate Linked to Poor Educational Attainment in ChildhoodApril 09, 2018
In utero exposure to AEDs in combination, or sodium valproate alone, is associated with a significant decrease in attainment in national educational tests for 7-year-old children.
The adjusted analysis also demonstrated that the code stroke system was associated with a decreased risk for post-stroke epilepsy within 5 years of stroke.
A reasonable proportion of patients with epilepsy who have received treatment with pharmaceutical-grade cannabidiol products along with antiepileptic drugs have experienced a decrease in seizure frequency.
An inverse relation was observed between epilepsy and cerebral palsy and 5-minute and 10-minute Apgar scores.
Modulate electrical stimulation of the amygdala may improve declarative memory without provoking any emotional reaction.
Ill-timed administration of benzodiazepine treatment in pediatric patients with refractory convulsive status epilepticus is associated with many short-term adverse events.
Non-pharmaceutical treatments improved 4 cognitive and behavioral domains in children with epilepsy.
Women on AEDs during pregnancy are at a higher risk of delivering prematurely and giving birth to SGA newborns.
The guideline highlights the incidence, risk factors, and preventive approaches of SUDEP.
Cannabidiol appears to reduce seizures for some patients with Lennox-Gastaut syndrome.
Taking epilepsy medication after a first seizure decreases the risk of another seizure.
Folic acid supplementation at least one month prior to conception is recommended.
Physician assistant evaluation revealed disorder's true source.
The seizures began following surgery to repair a cerebrospinal fluid leak.
Vimpat is used in the treatment of partial-onset seizures.