Generic Name and Formulations:
Felodipine 2.5mg, 5mg, 10mg; ext rel tabs.
Various generic manufacturers
Indications for Felodipine:
Take without food or with a light meal. Do not crush or chew. Initially 5mg once daily. Range 2.5–10mg once daily. Adjust at 2 week intervals; max 10mg daily. Elderly or hepatic dysfunction: initially 2.5mg once daily.
Heart failure. Hepatic impairment. Maintain good dental hygiene. Elderly. Pregnancy (Cat.C). Nursing mothers: not recommended.
Calcium channel blocker (CCB) (dihydropyridine).
May increase metoprolol, tacrolimus levels. Potentiated by cimetidine. Increased bioavailability with grapefruit juice. Levels decreased with long-term anticonvulsants (eg, carbamazepine, phenytoin, phenobarbital), consider alternate antihypertensive therapy.
Peripheral edema, headache, flushing, dizziness, respiratory symptoms, weakness, cough, GI upset, gynecomastia; hypotension, tachycardia, syncope, MI, angina, gingival hyperplasia (rare).
Formerly known under the brand name Plendil.