Gastroenterology Information Center Archive
The probiotic Lactobacillus reuteri DSM17938 may be useful for managing colic in breastfed infants; however, its efficacy in formula-fed infants is unclear.
No benefits seen with Lactobacillus rhamnosus GG or L. rhamnosus R0011 and L. helveticus R0052.
Item-reduced version with 8 questions instead of 28 accounted for 77% of variance.
A great deal of progress has been made in reducing the burden of diarrheal diseases, but this reduction has not been equal globally.
FPIES is a gastrointestinal food-associated hypersensitivity that often affects infants and toddlers and is marked by vomiting, diarrhea, fatigue, and pallor.
Roux-en-Y gastric bypass is associated with greater weight loss at 1, 3, and 5 years than sleeve gastrectomy or adjustable gastric banding.
Psoriasis appears to be significantly associated with inflammatory bowel disease.
Probiotics provided to reduce the risk for common acute infections may be associated with reduced antibiotic use in infants and children.
Loss to follow-up is common with inflammatory bowel disease, and both low C-reactive protein levels and long travel time to the hospital are predictors of follow-up loss
Unrestricted diets are acceptable more than one day before colonoscopy among patients using a split-dose bowel regimen.
The recommendations have been published in the AGA's official journal, Gastroenterology.
Recommendations include clinician education, use of gastric pH measurement, radiographs.
The consumption of dietary gluten was not associated with microscopic colitis risk in patients without celiac disease.
Study authors at the American College of Gastroenterology (ACG) Scientific Meeting 2018 presented late-breaking data from the induction phase of the Phase 3 UNIFI study.
The test works by measuring levels of anti-cytolethal distending toxin B (CdtB) and anti-vinculin, 2 biomarkers of post-infectious IBS-D and IBS-M.
In patients taking multiple antibiotics, proton pump inhibitors, or histamine receptor antagonists, the concurrent use of probiotics was associated with an increased incidence of Clostridium difficile infection
In one study, 86% of patients clinically diagnosed with esophagopharyngeal reflux reported significant reduction in symptoms after 2 weeks of use.
Correlation between PPI and hip fracture persisted for subgroups with low, medium, high PPI use.
Intraductal papillary mucinous neoplasms and numerous gastrointestinal tumors have been linked to somatic gain-of-function GNAS mutations, which can lead to McCune-Albright syndrome.
Eravacycline was well-tolerated in clinical trials and achieved high cure rates in patients with Gram-negative pathogens (including resistant strains).
While several secretagogues have been recently approved by the Food and Drug Administration (FDA), a lack of head-to-head trials led researchers to conduct a systematic review to compare the effectiveness of these agents in patients with IBS-C.
Diagnosing, but leaving these polyps can save time and, likely, costs.
The American Society for Metabolic and Bariatric Surgery Pediatric Committee has updated their 2012 evidence-based guidelines.
The FDA has set a Prescription Drug User Fee Act target date of April 1, 2019.
High-dose esomeprazole taken in combination with aspirin may safely and effectively improve outcomes in patients with Barrett esophagus.
As fecal microbiota transplantation has been found to be effective in treating a number of gastrointestinal diseases, such as Clostridium difficile infection, researchers are now assessing whether it may also be effective for patients with irritable bowel syndrome.
A significant decline in rotavirus disease-associated hospitalization, emergency department visits, and physician office visits was demonstrated in children younger than 5 years following implementation of the rotavirus vaccine.
AGREE [A Working Group on PPI-REE) was convened to update the previously published guidelines on diagnostic criteria for eosinophilic esophagitis.
Interrelationship Between Celiac Disease, Self-Reported Wheat Sensitivity, and Functional GI Disorders
Individuals with clinically diagnosed celiac disease are at greater risk for chronic gastrointestinal symptoms, possibly fitting modified Rome criteria for irritable bowel syndrome and functional dyspepsia.
Fidaxomicin demonstrated the strongest evidence for being the most effective treatment in providing a long-term cure for C difficile infection.
Positive guaiac fecal occult blood test result linked to increased risk of death from circulatory, respiratory, other diseases.
No harms-related data reported for 28% of trials; safety results not reported for 37%.
Illnesses appear to be caused by Vibrio parahaemolyticus bacteria.
A study was conducted to evaluate the oxazolidinone resistance mechanisms of enterococci bacteria.
The budesonide extended-release formulation was found to be safe and well tolerated for the remission of ulcerative colitis, regardless of age or gender.
A 2-week course of treatment with rifaximin for diarrhea-predominant irritable bowel syndrome was found to improve abdominal pain symptoms.
The CDC has identified an increasing number of Shigella isolates that test within the susceptible range for the fluoroquinolone antibiotic ciprofloxacin.
Findings based on examination of 30-day postoperative period in large cohort
The American Academy of Pediatrics releases a new clinical report on the diagnosis and treatment of clinically significant gastroesophageal reflux.
In women, risk declines as levels increase up to 100 nmol/L, but association in men not significant
Elevated risk of overweight for formula-fed infants attenuated with adjustment for gut microbiota
Average-risk adults aged 45 should undergo high-sensitivity stool-based test, structural exam
Recognizing the obesity epidemic and educating physician assistants on the implications of this condition and how they should be caring for obese patients should be prioritized, according to the study authors.
Risk not increased for non-advanced adenoma found on colonoscopy following flex sigmoidoscopy
Absolute risks for colorectal cancer, CRC death not reduced for screening group vs controls in women
Heavy use in Crohn's, heavy or moderate use in ulcerative colitis tied to increased risk of death
Antibiotic treatment for Helicobacter pylori in patients who underwent endoscopic resection of early-stage gastric cancer or high-grade adenoma is associated with a reduced rate of metachronous gastric cancer.
Patients with type 2 diabetes have a greater risk for developing inflammatory bowel disease when using dipeptidyl peptidase-4 inhibitors.
Short-term proton pump inhibitors (PPIs) are linked to an elevated risk for hip fracture among patients with Alzheimer's disease. No link is seem among patients taking long-term or cumulative PPIs.
Investigators found more frequent appendicitis, appendectomy codes in the first week following colonoscopy than the next 51 weeks.
An outbreak of E. coli O157:H7 have been reported in 13 states in the US as well as Canada.
Oral capsule FMT and colonoscopy delivery showed similar patient outcomes, low rate differences, and high success rates.
Patients with irritable bowel syndrome found FODMAP more beneficial than general dietary advice
The meta-analysis showed that short-term probiotic supplementation reduced body weight, BMI, and fat percentage, but the effect sizes were small.
The data suggest possible variability across NOACs regarding gastrointestinal bleeding risk, with an increased risk associated with rivaroxaban and dabigatran.
The researchers found that patients receiving adjuvant chemotherapy for gastroesophageal adenocarcinoma were younger, more likely to have advanced disease, and had shorter postoperative inpatient stays.
The association is partially mediated by levels of anxiety and depressive symptoms.
Patient-level interventions include changes to invitation, giving results or follow-up appointments, and patient navigators, and provider-level interventions include reminders or performance data.
The 12-year results show that Roux-en-Y gastric bypass offered long-term durability of weight loss and was associated with fewer obesity-related coexisting conditions compared with those who did not have the surgery.
Patients with childhood-onset IBD have an increased risk of cancer, especially gastrointestinal cancers, lymphoid neoplasms, and skin cancer,
A PEG low-volume regimen is similar to a PEG high-volume regimen for colon cleansing in patients with IBS.
Incidence of pneumonia was higher among patients with GERD compared with matched controls.
Clinical pathway to improve care of acute gastroenteritis patients is associated with a sustained reduction in IV fluid use and length of stay in the pediatric emergency department.
Asthma was associated with Crohn's disease and with early- and late-onset ulcerative colitis.
Researchers analyzed colorectal cancer mortality rates among individuals between 20 and 54 years of age from 1970 through 2014.
The addition of oats to a gluten-free diet did not affect symptoms, histology, immunity, or serologic features in patients with celiac disease.
Environmental risk factors that predispose people to inflammatory bowel disease may have a stronger effect in children than adults.
Researchers found that a cash incentive of $100 was associated with increased colorectal screening rates in eligible adults.
Many adverse events could be avoidable with more judicious use of antibiotics.
Serum TG2A screening has a positive predictive value of 61% to detect celiac disease.
An increased ADR is associated with an adjusted hazard ratio of 0.63 for interval colorectal cancer and 0.50 for cancer death.
Interferon- concentrations and THELPER cells are significantly reduced during symptom flares.
Risk of death is increased among those without gastrointestinal conditions and with prolonged use.
The score could help predict advanced colorectal neoplasia in adults younger than 50 years of age.
The guideline is intended to be an educational device to provide information that may assist endoscopists in providing care to patients.
Findings show that bacteria from mothers' breast milk and areolar skin are transferred to their infants' guts.
The new device uses magnetic catheters to draw the upper and lower esophagus together.
However, duodenal integrity appears to not be affected in eosinophilic esophagitis.
Gluten-rich food may lead to symptom onset, specifically early satiety, in patients with functional dyspepsia.
Treatment was effective in patients under 6 years who received 50 mg/day of zinc as an initial dose.
Almost half of participants reported that they never received information regarding the side effects of their medication from their prescriber.
Avoiding gluten may result in reduced consumption of beneficial whole grains that could affect cardiovascular risk.
A follow-up colonoscopy more than 10 months after a positive FIT result is associated with a higher risk of colorectal cancer and more advanced disease at the time of diagnosis.
Increasing duration of antibiotic use at ages 20 to 39 and 40 to 59 is significantly associated with an increased risk of colorectal adenoma.
Apixaban is associated with a lower risk of gastrointestinal bleeding than rivaroxaban or dabigatran.
Celiac disease is associated with anorexia nervosa before and after a diagnosis of celiac disease.
The test will provide information on an individual's genetic predisposition to 10 diseases or conditions.
The USPSTF evaluated the benefits and harms of screening vs not screening, targeted vs universal screening, and treatment for celiac disease.
A meta-analysis suggests that patients who take gastric acid suppressants may have a higher risk for recurrent CDI.
Researchers identified 5 factors that identify patients with IBD at high risk for hospitalization, emergency department visits, and high treatment charges in the next year.
Octogenarians with colorectal cancer have several differences in clinical and tumor characteristics, compared with younger patients with the disease.
Budesonide oral suspension treatment improved symptomatic, endoscopic, and histologic parameters in eosinophilic esophagitis.
The FDA has received 120 reports of serious cases of pancreatitis or death after the approval of Viberzi in May 2015.
Excess weight could influence the risk of of gastrointestinal cancers by altering insulin levels and promoting inflammation.
Implementation of the FODMAP diet is an effective strategy to manage symptoms of IBS, including bloating and abdominal pain.
Thirty-eight of 231 NCGS patients showed gluten-specific symptoms when completing the placebo-controlled gluten challenge.
Individuals who consume the least amount of gluten are more likely to develop type 2 diabetes.
The American College of Gastroenterology has released recommendations of preferred approaches for diagnosing and evaluating patients with abnormal liver test results.
Among GERD patients, the mean annual ARI episode dropped from 4.39 during the year before PPI treatment to 3.89 after treatment with a PPI.
Trulance has been approved for the treatment of chronic idiopathic constipation in adults.