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News

GI Bleed Hospitalization Risk Linked to Oral Anticoagulant Choice, PPI Cotherapy

GI Bleed Hospitalization Risk Linked to Oral Anticoagulant Choice, PPI Cotherapy

To compare the incidence of hospitalization for upper GI tract bleeding, researchers used US Medicare beneficiary files to identify a cohort of patients that were ≥30 years old who initiated oral anticoagulation therapy with apixaban, dabigatran, rivaroxaban, or warfarin, with or without PPI cotherapy.

Novel H. pylori Eradication Therapy Effective in Phase 3 Trial

The ERADICATE Hp2 trial enrolled 455 dyspepsia patients at 55 sites across the US and randomized them to receive 4 capsules, 3 times daily, of either Talicia or the active comparator (amoxicillin 250mg and omeprazole 10mg), for a period of 14 days.

Low-Dose Imipramine Alternative Treatment for Refractory Functional Dyspepsia

Low-dose imipramine, a tricyclic antidepressant, may benefit patients with functional dyspepsia that is unresponsive to proton pump inhibitors and prokinetic agents.

Opinion

Bowel Preparation for Colorectal Cancer Screening: Improving Outcomes

Stool burden can be a particularly challenging aspect of colonoscopies, making potentially cancerous lesions easier to miss.

Acute abdominal pain, fever may signify diverticulitis

In older patients who complain of fever and lower abdominal pain, consider diverticulitis, especially if the patient has a previous diagnosis of diverticulosis.

Features

Irritable Bowel Syndrome and Vitamin D: Is There a Connection?

Irritable Bowel Syndrome and Vitamin D: Is There a Connection?

Low vitamin D levels have been linked to multiple diseases including some cancers, neurologic disorders, decrease in bone density, and cognitive decline in the elderly, and research suggests that a possible inflammatory response in the gut when vitamin D levels are low may cause irritable bowel syndrome.

Inflammatory Arthritis and the Gut Microbiome: Do Microbes Hold the Key to New Treatments?

Inflammatory Arthritis and the Gut Microbiome: Do Microbes Hold the Key to New Treatments?

Recent research points to an association between the gut microbiome composition and various types of immune-mediated inflammatory arthritides.

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