Intraductal papillary mucinous neoplasms and numerous gastrointestinal tumors have been linked to somatic gain-of-function GNAS mutations, which can lead to McCune-Albright syndrome.
While several secretagogues have been recently approved by the Food and Drug Administration (FDA), a lack of head-to-head trials led researchers to conduct a systematic review to compare the effectiveness of these agents in patients with IBS-C.
Eravacycline was well-tolerated in clinical trials and achieved high cure rates in patients with Gram-negative pathogens (including resistant strains).
Diagnosing, but leaving these polyps can save time and, likely, costs.
The American Society for Metabolic and Bariatric Surgery Pediatric Committee has updated their 2012 evidence-based guidelines.
The FDA has set a Prescription Drug User Fee Act target date of April 1, 2019.
High-dose esomeprazole taken in combination with aspirin may safely and effectively improve outcomes in patients with Barrett esophagus.
Patients who received gastric bypass surgery had lower rates of diabetic neuropathy at follow up that remained stable throughout the study.
As fecal microbiota transplantation has been found to be effective in treating a number of gastrointestinal diseases, such as Clostridium difficile infection, researchers are now assessing whether it may also be effective for patients with irritable bowel syndrome.
A significant decline in rotavirus disease-associated hospitalization, emergency department visits, and physician office visits was demonstrated in children younger than 5 years following implementation of the rotavirus vaccine.
AGREE [A Working Group on PPI-REE) was convened to update the previously published guidelines on diagnostic criteria for eosinophilic esophagitis.
Interrelationship Between Celiac Disease, Self-Reported Wheat Sensitivity, and Functional GI DisordersJuly 20, 2018
Individuals with clinically diagnosed celiac disease are at greater risk for chronic gastrointestinal symptoms, possibly fitting modified Rome criteria for irritable bowel syndrome and functional dyspepsia.
Fidaxomicin demonstrated the strongest evidence for being the most effective treatment in providing a long-term cure for C difficile infection.
Positive guaiac fecal occult blood test result linked to increased risk of death from circulatory, respiratory, other diseases.
No harms-related data reported for 28% of trials; safety results not reported for 37%.
Illnesses appear to be caused by Vibrio parahaemolyticus bacteria.
A study was conducted to evaluate the oxazolidinone resistance mechanisms of enterococci bacteria.
The budesonide extended-release formulation was found to be safe and well tolerated for the remission of ulcerative colitis, regardless of age or gender.
A 2-week course of treatment with rifaximin for diarrhea-predominant irritable bowel syndrome was found to improve abdominal pain symptoms.
The CDC has identified an increasing number of Shigella isolates that test within the susceptible range for the fluoroquinolone antibiotic ciprofloxacin.
Findings based on examination of 30-day postoperative period in large cohort
The American Academy of Pediatrics releases a new clinical report on the diagnosis and treatment of clinically significant gastroesophageal reflux.
Restricting perioperative fluid for abdominal surgery patients does not reduce complications: The RELIEF trialJune 19, 2018
Among patients at increased risk for complications undergoing abdominal surgery, those randomized to perioperative fluid restriction did not have increased disability-free survival at one year compared to patients who received liberal perioperative fluid management.
In women, risk declines as levels increase up to 100 nmol/L, but association in men not significant
A 90-year-old woman with a history of coronary disease and gallstones presents to the emergency department with generalized abdominal pain that started suddenly about 7 hours prior.
Elevated risk of overweight for formula-fed infants attenuated with adjustment for gut microbiota
Average-risk adults aged 45 should undergo high-sensitivity stool-based test, structural exam
Recognizing the obesity epidemic and educating physician assistants on the implications of this condition and how they should be caring for obese patients should be prioritized, according to the study authors.
Risk not increased for non-advanced adenoma found on colonoscopy following flex sigmoidoscopy
Some include mechanical complications, central vascular access complications, and compatibility issues.