Gastroenterology

Postpartum New-Onset Mental Illness Risk Up With IBD

Postpartum New-Onset Mental Illness Risk Up With IBD

Increased risk for new-onset, postpartum mental illness observed in patients with inflammatory bowel disease.

High Fiber Intake Tied to Lower Risk for Noncommunicable Disease

High Fiber Intake Tied to Lower Risk for Noncommunicable Disease

Reduction in risk for range of critical outcomes greatest for daily dietary fiber intake of 25 to 29 g.

Biosimilar Infliximab CT-P13 Similar to Reference Infliximab for Crohn Disease

Biosimilar Infliximab CT-P13 Similar to Reference Infliximab for Crohn Disease

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Patients with Crohn disease were enrolled in a comparative cohort study that analyzed the outcomes of reference product infliximab vs biosimilar treatment.

Fewer Complications Found With Hybrid Surgery for Esophageal Cancer

Fewer Complications Found With Hybrid Surgery for Esophageal Cancer

Incidence of intraoperative, postoperative complications lower in resectable esophageal cancer.

Resistance to Clarithromycin, Metronidazole Affects <i>H pylori</i> Eradication

Resistance to Clarithromycin, Metronidazole Affects H pylori Eradication

Minimum inhibitory concentration levels of resistance to either clarithromycin or metronidazole may play a role in Helicobacter pylori therapy outcome.

Fecal Transplant in Managing Immune Checkpoint Inhibitor-Associated Colitis

Fecal Transplant in Managing Immune Checkpoint Inhibitor-Associated Colitis

Transplanting fecal bacteria from healthy donors might prove to be effective in resolving cancer immunotherapy-triggered colitis, a pair of case reports has suggested.

Negative Colonoscopy Findings Linked to Lower Risk of Colorectal Cancer, Related Deaths

Negative Colonoscopy Findings Linked to Lower Risk of Colorectal Cancer, Related Deaths

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Compared with unscreened individuals, a colonoscopy with normal findings may be linked to lower risk of colorectal cancer deaths for more than 12 years.

Anemia Criteria Assist Decision on Type of Colorectal Cancer Screen

Anemia Criteria Assist Decision on Type of Colorectal Cancer Screen

Risk for proximal cancers low among patients without broad-definition anemia and/or abdominal mass.

GI Microbiota and Carbapenem-Resistant <I>Pseudomonas aeruginosa</i> Colonization Risk

GI Microbiota and Carbapenem-Resistant Pseudomonas aeruginosa Colonization Risk

Decreases in abundance of several taxa may be linked to increased risk for carbapenem-resistant P aeruginosa colonization-acquisition ICU patients.

Effect of Omega-3 Fatty Acid and/or Aspirin on Colorectal Adenoma Prevention

Effect of Omega-3 Fatty Acid and/or Aspirin on Colorectal Adenoma Prevention

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The omega-3 polyunsaturated fatty acid eicosapentaenoic acid and aspirin were compared alone and in combination against placebo for the prevention of colorectal cancer.

Patients Uncomfortable Stopping Colorectal Cancer Screening Despite Low Value

Patients Uncomfortable Stopping Colorectal Cancer Screening Despite Low Value

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Some patients may not be comfortable discontinuing colorectal cancer screening despite minimal benefit associated with the testing.

Certain Sites of Brain Lesions in MS Tied to Bowel Incontinence

Certain Sites of Brain Lesions in MS Tied to Bowel Incontinence

Left hemisphere dominates sensory visceral integration, right tied to the autonomic function.

Irritable Bowel Syndrome and Vitamin D: Is There a Connection?

Irritable Bowel Syndrome and Vitamin D: Is There a Connection?

Low vitamin D levels have been linked to multiple diseases including some cancers, neurologic disorders, decrease in bone density, and cognitive decline in the elderly, and research suggests that a possible inflammatory response in the gut when vitamin D levels are low may cause irritable bowel syndrome.

GI Bleed Hospitalization Risk Linked to Oral Anticoagulant Choice, PPI Cotherapy

GI Bleed Hospitalization Risk Linked to Oral Anticoagulant Choice, PPI Cotherapy

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To compare the incidence of hospitalization for upper GI tract bleeding, researchers used US Medicare beneficiary files to identify a cohort of patients that were ≥30 years old who initiated oral anticoagulation therapy with apixaban, dabigatran, rivaroxaban, or warfarin, with or without PPI cotherapy.

Novel <i>H. pylori</i> Eradication Therapy Effective in Phase 3 Trial

Novel H. pylori Eradication Therapy Effective in Phase 3 Trial

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The ERADICATE Hp2 trial enrolled 455 dyspepsia patients at 55 sites across the US and randomized them to receive 4 capsules, 3 times daily, of either Talicia or the active comparator (amoxicillin 250mg and omeprazole 10mg), for a period of 14 days.

Low-Dose Imipramine Alternative Treatment for Refractory Functional Dyspepsia

Low-Dose Imipramine Alternative Treatment for Refractory Functional Dyspepsia

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Low-dose imipramine, a tricyclic antidepressant, may benefit patients with functional dyspepsia that is unresponsive to proton pump inhibitors and prokinetic agents.

Inflammatory Arthritis and the Gut Microbiome: Do Microbes Hold the Key to New Treatments?

Inflammatory Arthritis and the Gut Microbiome: Do Microbes Hold the Key to New Treatments?

Recent research points to an association between the gut microbiome composition and various types of immune-mediated inflammatory arthritides.

Probiotic Found to Be Effective for Colic in Breastfed Infants

Probiotic Found to Be Effective for Colic in Breastfed Infants

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The probiotic Lactobacillus reuteri DSM17938 may be useful for managing colic in breastfed infants; however, its efficacy in formula-fed infants is unclear.

Probiotics Show No Benefits for Pediatric Acute Gastroenteritis

Probiotics Show No Benefits for Pediatric Acute Gastroenteritis

No benefits seen with Lactobacillus rhamnosus GG or L. rhamnosus R0011 and L. helveticus R0052.

IBD Disability Index for Self-Report Reliable, Valid

IBD Disability Index for Self-Report Reliable, Valid

Item-reduced version with 8 questions instead of 28 accounted for 77% of variance.

Diarrhea Remains Leading Cause of Global Mortality and Morbidity

Diarrhea Remains Leading Cause of Global Mortality and Morbidity

A great deal of progress has been made in reducing the burden of diarrheal diseases, but this reduction has not been equal globally.

Avocado Implicated in Several Food Protein-Induced Enterocolitis Syndrome Cases

Avocado Implicated in Several Food Protein-Induced Enterocolitis Syndrome Cases

FPIES is a gastrointestinal food-associated hypersensitivity that often affects infants and toddlers and is marked by vomiting, diarrhea, fatigue, and pallor.

Greater Weight Loss With Gastric Bypass Than Other Bariatric Surgery

Greater Weight Loss With Gastric Bypass Than Other Bariatric Surgery

Roux-en-Y gastric bypass is associated with greater weight loss at 1, 3, and 5 years than sleeve gastrectomy or adjustable gastric banding.

Psoriasis Linked to Increased Risk for Inflammatory Bowel Disease

Psoriasis Linked to Increased Risk for Inflammatory Bowel Disease

Psoriasis appears to be significantly associated with inflammatory bowel disease.

Probiotics, Depression, and the Role of Inflammation

Probiotics, Depression, and the Role of Inflammation

Researchers examined evidence suggesting that probiotics may exert antidepressant effects via anti-inflammatory mechanisms.

Probiotics May Reduce Antibiotic Use for Common Acute Infections in Children

Probiotics May Reduce Antibiotic Use for Common Acute Infections in Children

Probiotics provided to reduce the risk for common acute infections may be associated with reduced antibiotic use in infants and children.

Loss to Follow-Up Common With IBD

Loss to Follow-Up Common With IBD

Loss to follow-up is common with inflammatory bowel disease, and both low C-reactive protein levels and long travel time to the hospital are predictors of follow-up loss

Unrestricted Diet Acceptable More Than One Day Before Colonoscopy

Unrestricted Diet Acceptable More Than One Day Before Colonoscopy

Unrestricted diets are acceptable more than one day before colonoscopy among patients using a split-dose bowel regimen.

AGA: New Opioid-Induced Constipation Management Guidelines Available

AGA: New Opioid-Induced Constipation Management Guidelines Available

The recommendations have been published in the AGA's official journal, Gastroenterology.

Recommendations Developed to Verify Nasogastric Tube Placement in Children

Recommendations Developed to Verify Nasogastric Tube Placement in Children

Recommendations include clinician education, use of gastric pH measurement, radiographs.

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