Gastrointestinal Illnesses

GI Microbiota and Carbapenem-Resistant <I>Pseudomonas aeruginosa</i> Colonization Risk

GI Microbiota and Carbapenem-Resistant Pseudomonas aeruginosa Colonization Risk

Decreases in abundance of several taxa may be linked to increased risk for carbapenem-resistant P aeruginosa colonization-acquisition ICU patients.

GI Bleed Hospitalization Risk Linked to Oral Anticoagulant Choice, PPI Cotherapy

GI Bleed Hospitalization Risk Linked to Oral Anticoagulant Choice, PPI Cotherapy

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To compare the incidence of hospitalization for upper GI tract bleeding, researchers used US Medicare beneficiary files to identify a cohort of patients that were ≥30 years old who initiated oral anticoagulation therapy with apixaban, dabigatran, rivaroxaban, or warfarin, with or without PPI cotherapy.

Low-Dose Imipramine Alternative Treatment for Refractory Functional Dyspepsia

Low-Dose Imipramine Alternative Treatment for Refractory Functional Dyspepsia

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Low-dose imipramine, a tricyclic antidepressant, may benefit patients with functional dyspepsia that is unresponsive to proton pump inhibitors and prokinetic agents.

Probiotics Show No Benefits for Pediatric Acute Gastroenteritis

Probiotics Show No Benefits for Pediatric Acute Gastroenteritis

No benefits seen with Lactobacillus rhamnosus GG or L. rhamnosus R0011 and L. helveticus R0052.

McCune-Albright Syndrome Linked to Broad Range of Gastrointestinal Pathologies

McCune-Albright Syndrome Linked to Broad Range of Gastrointestinal Pathologies

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Intraductal papillary mucinous neoplasms and numerous gastrointestinal tumors have been linked to somatic gain-of-function GNAS mutations, which can lead to McCune-Albright syndrome.

Rotavirus Vaccination Linked to Decrease in Hospitalizations

Rotavirus Vaccination Linked to Decrease in Hospitalizations

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A significant decline in rotavirus disease-associated hospitalization, emergency department visits, and physician office visits was demonstrated in children younger than 5 years following implementation of the rotavirus vaccine.

Updated Diagnostic Guidelines for Eosinophilic Esophagitis: Outcomes From AGREE

Updated Diagnostic Guidelines for Eosinophilic Esophagitis: Outcomes From AGREE

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AGREE [A Working Group on PPI-REE) was convened to update the previously published guidelines on diagnostic criteria for eosinophilic esophagitis.

Metachronous gastric cancer risk reduced with <i>H pylori</i> treatment

Metachronous gastric cancer risk reduced with H pylori treatment

Antibiotic treatment for Helicobacter pylori in patients who underwent endoscopic resection of early-stage gastric cancer or high-grade adenoma is associated with a reduced rate of metachronous gastric cancer.

Primary gastrinomas of the hepatobiliary tract may occur in patients with Zollinger-Ellison syndrome

Primary gastrinomas of the hepatobiliary tract may occur in patients with Zollinger-Ellison syndrome

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Lymph nodes proximal to hepatic or biliary gastrinomas will likely require extraction as many in the surround region will have metastasized.

Appendicitis risk greater one week after colonoscopy

Appendicitis risk greater one week after colonoscopy

Investigators found more frequent appendicitis, appendectomy codes in the first week following colonoscopy than the next 51 weeks.

Dabigatran, rivaroxaban associated with increased risk of major gastrointestinal bleeding

Dabigatran, rivaroxaban associated with increased risk of major gastrointestinal bleeding

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The data suggest possible variability across NOACs regarding gastrointestinal bleeding risk, with an increased risk associated with rivaroxaban and dabigatran.

Clinical pathway beneficial for pediatric acute gastroenteritis

Clinical pathway beneficial for pediatric acute gastroenteritis

Clinical pathway to improve care of acute gastroenteritis patients is associated with a sustained reduction in IV fluid use and length of stay in the pediatric emergency department.

Patients diagnosed with upper functional gastroenterology disorders often have irritable bowel syndrome

Patients diagnosed with upper functional gastroenterology disorders often have irritable bowel syndrome

The risk factors for IBS-FD overlap deserve more concern, according to the authors.

Oral contraceptives increase surgery risk for women with Crohn disease

Oral contraceptives increase surgery risk for women with Crohn disease

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Women with Crohn disease who use oral contraceptives for more than 1 year have an increased risk of surgery.

Greater gluten intake before age 2 may increase risk of celiac disease

Greater gluten intake before age 2 may increase risk of celiac disease

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High gluten intake during the first 2 years of life was associated with an increased risk of celiac disease during childhood.

Stat Consult: Norovirus 
infection

Stat Consult: Norovirus 
infection

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Norovirus is the leading cause of both sporadic and epidemic gastroenteritis worldwide.

FDA approves two new therapies for irritable bowel syndrome

FDA approves two new therapies for irritable bowel syndrome

Two new therapies to treat irritable bowel syndrome, eluxadoline and rifaximin, have been approved by the FDA.

Evidence supporting herbal meds for GI disorders lacking

Evidence supporting herbal meds for GI disorders lacking

Limited evidence and a lack of quality control for manufacturing practices cast doubt on the use of herbal medicines for gastrointestinal conditions.

Managing anal fissures

Managing anal fissures

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Anal fissures can be confused with hemorrhoids in everyday primary practice but require their own treatment protocol.

Non-TNF blocker for colitis, Crohn disease

Non-TNF blocker for colitis, Crohn disease

Entyvio can be used to treat ulcerative colitis and Crohn disease in adults who did not have success with other treatments.

Asthma, COPD linked with more inflammatory bowel disease

Asthma, COPD linked with more inflammatory bowel disease

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People with airway diseases are more likely to have inflammatory bowel disease.

Low-dose aspirin risks negate benefits in women

Low-dose aspirin risks negate benefits in women

Although women who took low-dose aspirin saw a small reduction of CVD and colorectal cancer risk, the risk of gastrointestinal bleeding increased.

Yoga may ease inflammatory bowel disease

Yoga may ease inflammatory bowel disease

Trends observed toward improvement in health-related quality of life and self-efficacy in children.

Vancomycin prophylaxis may reduce C. diff recurrence

Vancomycin prophylaxis may reduce C. diff recurrence

Prophylactic vancomycin twice per day has been effective in reducing the rate of C. difficile in high-risk patients aged 65 years and older.

FDA is now enforcing its gluten-free standards

FDA is now enforcing its gluten-free standards

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Manufacturers are now subject to scrutiny and could be subject to regulatory action if gluten-free labels are not consistent with agency standards.

CDC: Beware of antibiotic resistance in foodborne pathogens

CDC: Beware of antibiotic resistance in foodborne pathogens

The rate of resistance to quinolone drugs in Salmonella typhi rose to 68% in 2012.

Vedolizumab approved to treat ulcerative colitis, Crohn disease

Vedolizumab approved to treat ulcerative colitis, Crohn disease

The FDA has approved vedolizumab for patients with inadequate response to conventional therapies.

Help for kids with new Crohn's disease

Help for kids with new Crohn's disease

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Early monotherapy with such anti-TNF-alpha agents as infliximabor and adalimumab may produce better overall clinical and growth outcomes.

Constipation does not cause diverticulosis

Constipation does not cause diverticulosis

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Colonoscopy results and assessment of diet, physical activity and bowel habits revealed no association between constipation and an increased risk of diverticulosis.

Intussusception risk still up with rotavirus vax

Intussusception risk still up with rotavirus vax

Intussusception risk is slightly higher in post-licensure studies than previously reported, but not enough to change clinical practice.

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