Hematology/Oncology News Archive
Diagnosing, but leaving these polyps can save time and, likely, costs.
No increased risk of cancer recurrence among RA patients initiating tumor necrosis factor inhibitor treatment.
Few differences between rural, urban patients in cancer outcomes with uniform access to cancer care.
Cytology recommended every 3 years from age 21; different screening options from age 30 to 65.
A Phase 1 study in healthy volunteers showed a favorable safety profile with no serious adverse events.
Lumpectomy, radiotherapy tied to reduction in breast cancer mortality vs lumpectomy, mastectomy.
The majority of patients with cancer who are being treated with World Health Organization Step III opioids were found to experience poor sleep quality, often due to pain.
In high-volume centers, patients with liver metastases from colorectal cancer may often be eligible for minimally invasive liver surgery via laparoscopy, thereby reducing potential morbidity risks associated with open surgery.
For cancers associated with numerous copy number changes, it is difficult to assign disease classifiers and identify useful targets for drug development.
Short intervention associated with more sunscreen use, improved patient satisfaction.
High-dose esomeprazole taken in combination with aspirin may safely and effectively improve outcomes in patients with Barrett esophagus.
C-509T allele and postoperative cosmetic surgery significantly linked to breast fibrosis risk.
No increased risk of corpus uteri, invasive breast cancer for women undergoing assisted reproduction.
Studies conducted in people have mixed results, with some indication of increased risk of ovarian cancer.
Less than a year following the initial direct-to-tumor vaccine injection, all treated tumors disappeared.
Ribociclib approved in combo with AI as endocrine tx for HR-positive, HER2-negative advanced breast CA.
10 autoantibody biomarkers together display high sensitivity, specificity.
The use of multiple sun protection measures was defined as the use of 2 or more of these measures more than 50% of the time when the individual was outdoors.
Positive guaiac fecal occult blood test result linked to increased risk of death from circulatory, respiratory, other diseases.
The Endocrine Society, European Society of Endocrinology, and Pediatric Endocrine Society issue guidelines for the management of hypothalamic-pituitary and growth disorders in childhood cancer survivors.
First-line chemotherapy in combination with bevacizumab, compared with chemotherapy alone, may benefit patients with ovarian cancer and elevated neutrophil-to-lymphocyte ratios.
An analysis of population data on cancer incidence, survival, and mortality revealed that early interventions and improvements to treatments contributed to a 26% decline in cancer deaths from 1991 to 2015.
No significant difference was identified in combination CA125/CEA ratio vs CEA alone in distinguishing ovarian neoplasms from ovarian metastases.
Study patients who received Avastin plus chemotherapy followed by Avastin alone, had a greater median PFS vs patients who received chemotherapy alone (18.2 months vs 12 months; hazard ratio [HR] 0.62, 95% CI, 0.52-0.75; P<.0001).
Reduced interest seen in minority and less educated populations.
Mirvetuximuab soravtansine uses a humanized FRα-binding antibody to target antibody-drug conjugates specifically to FRα-expressing cancer cells and a potent anti-tumor agent, DM4, to kill the targeted cancer cells.
Standardized definition, guidance on estimation may facilitate understanding of overdiagnosis.
Social media is an ideal platform to reach teenagers and young adults to encourage sun safety.
Investigators report results from the MONALEESA-7 trial, which assessed ribociclib plus endocrine therapy in premenopausal women with advanced breast cancer.
Greater reproducibility and higher concordance for melanoma staging with implementation of AJCC 8
The percentage of NPs who order the mt-sDNA test for colorectal cancer screening has increased significantly since the test became available in 2014.
Percutaneous ablation compared with partial, radical nephrectomy for 4,310 patients aged 66 years
Vivio can accurately detect cardiac dysfunction in anthracycline-exposed childhood cancer survivors
In women, risk declines as levels increase up to 100 nmol/L, but association in men not significant
Regardless of age, favorable survival conferred by an HPV-positive tumor status
From 2006 and 2016, smallest increase seen in high Sociodemographic Index countries.
Increased risk of subsequent diabetes independent of traditional diabetes risk factors
A smartphone application is a more effective learning tool for accurately diagnosing melanoma compared with traditional, rule-based methods.
A prophylactic, graded, extended infusion of carboplatin, compared with a shorter, standard infusion, is not associated with a reduced rate of HSRs in women with recurrent ovarian cancer.
Cryoablation also cuts the need for opioids at 24 hours post-treatment and at three months
Lyme neuroborreliosis diagnosis had no substantial effect on long-term survival, health, or educational/social functioning yet may be associated with an increased risk of hematologic and nonmelanoma skin cancers.
Alternative sun protection products, including pills and dietary supplements, are misleading consumers through false marketing and advertising.
In year 1, 13% did not undergo MRI or mammography; up to 19% by year 5.
Average-risk adults aged 45 should undergo high-sensitivity stool-based test, structural exam
In a case study, olaparib was found to induce folate deficiency in most patients with relapsed ovarian cancer. Researchers discuss the significance of this adverse effect and how it was managed.
Age at diagnosis, sex, BMI, and thyroid-stimulating hormone suppression therapy affect CVD risk
The American College of Cardiology, along with several other cardiology societies, have updated guidelines on best practices for improving safety when using ionizing radiation during cardiovascular imaging.
Findings for men with intermediate- and high-risk prostate cancer
Crossover in sex-specific rates among US non-Hispanic whites born since 1965
Grip strength is strongly and inversely associated with all-cause mortality and incidence of and mortality from cardiovascular disease, respiratory disease, COPD, all cancer, and subtypes of cancer, with associations being modestly stronger in the younger age groups.
Risk not increased for non-advanced adenoma found on colonoscopy following flex sigmoidoscopy
AAPA and SDPA respond to a recent article published in JAMA Dermatology.
But majority of oncologists don't feel knowledgeable enough to make these recommendations
For patients with platinum-sensitive recurrent ovarian cancer, trabectedin plus PLD may be beneficial.
Mice treated with 2-94 had few or no signs of lymphopenia or neutropenia, common adverse events associated with palbociclib.
The researchers enrolled 25 platinum-pretreated, immunotherapy-naïve patients with recurrent advanced epithelial ovarian cancer (EOC) for the trial.
Clinics claim unapproved therapies can treat number of diseases and conditions, including ALS and cancer
Significantly increased risk of malignant melanoma in males, but not females, on once-daily aspirin
Compared with dermatologists, physician assistants perform more skin biopsies but detect fewer melanomas.
Elevated risk of various cardiovascular outcomes, including pulmonary heart disease, atrial fibrillation
The USPSTF has updated its 2012 recommendations on prostate-specific antigen (PSA)-based screening for prostate cancer.
Intrathecal drug delivery systems and spinal cord stimulation have shown promise for the treatment of cancer pain in initial studies.
Absolute risks for colorectal cancer, CRC death not reduced for screening group vs controls in women
Pembrolizumab linked to significantly longer recurrence-free survival at 15-month follow-up
Advanced Ovarian Cancer Survival Rates Longer After Primary Cytoreductive Surgery Compared With Neoadjuvant Chemotherapy
Researchers found a superior survival rate in patients who received primary cytoreductive surgery as opposed to neoadjuvant chemotherapy for stage IIIC and IV high-grade serous ovarian carcinoma.
The FDA has approved Rubraca, a poly (ADP-ribose) polymerase inhibitor, to treat patients with epithelial ovarian, fallopian tube, or primary peritoneal cancer.
Genetic mutations assays using PapSEEK may facilitate the detection of certain cancers using fluids from Pap tests.
Vigil immunotherapy is possible for women with recurrent ovarian cancer and PARP 7 may impact ovarian cancer survival, according to two studies presented in New Orleans.
Prostate cancer was diagnosed more frequently in men who underwent single prostate-specific antigen screening than in those who did not, but mortality was unaffected.
The USPSTF has updated both the 2012 recommendation on behavioral counseling for the primary prevention of skin cancer and the 2009 recommendation on screening for skin cancer with skin self-examination.
Does weak evidence drive the NCCN recommendations of FDA-approved drugs?
Improving colorectal cancer screening rates among lower-income populations requires addressing structural, personal, and health care system barriers.
The use of the Mobile Patient Technology for Health-CRC (mPATH-CRC) digital health program doubles the proportion of patients who completed colorectal cancer (CRC) screening.
Colonoscopy is associated with significant reductions in colorectal cancer mortality among veterans and with greater benefit for left-sided cancer than right-sided cancer.
A higher concentration of plasma vitamin D is correlated with a decreased risk of total cancer.
For men with metastatic prostate cancer, aggressive therapy has no significant advantage over conservative androgen deprivation only treatments.
For patients with ovarian cancer taking pegylated liposomal doxorubicin who have hand-foot syndrome, frozen gloves and socks is a safe method of treatment.
The disease allele may be passed from affected grandmother to granddaughter through the father's inherited genes.
Cancer history has an important impact on mortality independent of cardiovascular risk factors.
An increased consumption of processed foods by 10% was associated with more than 10% increased risk for overall and breast cancers.
The use of oral contraceptives did not reduce the risks of breast cancer or colorectal cancer.
The USPSTF has issued an updated recommendation statement on ovarian cancer screening.
Primary gastrinomas of the hepatobiliary tract may occur in patients with Zollinger-Ellison syndrome
Lymph nodes proximal to hepatic or biliary gastrinomas will likely require extraction as many in the surround region will have metastasized.
Past epidemiological investigations resulted in inconsistent reports on the affiliation between antidepressants and the risk of ovarian cancer.
The addition of HIPEC resulted in longer recurrence-free and overall survival among patients with ovarian cancer.
A positive correlation between increased BMI and risk of prostate cancer recurrence was observed in patients undergoing radical prostatectomy.
Guidelines were provided for basal cell carcinoma and cutaneous squamous cell carcinoma.
Depressive symptoms at the time of treatment planning can predict overall 2 year mortality in patients with head and neck cancer.
Polygenic hazard scores were developed to help predict the age of onset of prostate cancer.
A multi-analyte blood test, CancerSEEK, can detect 8 common cancer types, with high sensitivity and specificity.
Both patients with and without BRCA mutations have comparable survival rates.
For women who work night shifts, breast cancer risks increase by 3.3% for every 5 years of work.
Patients with atopic dermatitis may have a greater risk of developing squamous cell carcinoma.
Breast cancer diagnosis is higher among women who currently use or recently used contemporary hormonal contraceptives than among women who have never used hormonal contraceptives.
Nivolumab treatment for non-small-cell lung cancer may induce successful depletion of HIV reservoir.
Body mass index is linked to malignant melanoma in men.
Oxybenzone, found in sunscreens and other products, has harmful dermatological and environmental effects.
New FDA-approved prophylactic treatment decreases bleeding episodes hemophilia A patients with factor VIII inhibitors.
According to a special report by the American Society of Clinical Oncology, alcohol consumption is a definite risk for cancer development.
Incidence rates of overweight- and obesity-related cancers have increased in the United States.