Hematology/Oncology News Archive

Ovarian cancer may be paternally inherited

The disease allele may be passed from affected grandmother to granddaughter through the father's inherited genes.

Cancer history affects mortality risk independent of CV risk

Cancer history has an important impact on mortality independent of cardiovascular risk factors.

Ultra-processed foods may increase overall, breast cancer risks

An increased consumption of processed foods by 10% was associated with more than 10% increased risk for overall and breast cancers.

Ovarian cancer risk reduced with oral contraceptives

The use of oral contraceptives did not reduce the risks of breast cancer or colorectal cancer.

Ovarian cancer screening: updated recommendations from the USPSTF

The USPSTF has issued an updated recommendation statement on ovarian cancer screening.

Primary gastrinomas of the hepatobiliary tract may occur in patients with Zollinger-Ellison syndrome

Lymph nodes proximal to hepatic or biliary gastrinomas will likely require extraction as many in the surround region will have metastasized.

Assessing the impact of antidepressants on ovarian cancer risk

Past epidemiological investigations resulted in inconsistent reports on the affiliation between antidepressants and the risk of ovarian cancer.

Ovarian cancer patients may benefit from added hyperthermic intraperitoneal chemotherapy

The addition of HIPEC resulted in longer recurrence-free and overall survival among patients with ovarian cancer.

Prostate cancer recurrence linked to metabolic syndrome, obesity

A positive correlation between increased BMI and risk of prostate cancer recurrence was observed in patients undergoing radical prostatectomy.

Guidelines for basal, cutaneous squamous cell carcinoma management

Guidelines were provided for basal cell carcinoma and cutaneous squamous cell carcinoma.

Depressive symptoms may predict mortality in head, neck cancer

Depressive symptoms at the time of treatment planning can predict overall 2 year mortality in patients with head and neck cancer.

Clinical tool may help in prostate cancer screenings

Polygenic hazard scores were developed to help predict the age of onset of prostate cancer.

Multi-analyte blood test detects 8 common cancers

A multi-analyte blood test, CancerSEEK, can detect 8 common cancer types, with high sensitivity and specificity.

BRCA might not affect young-onset breast cancer survival rates

Both patients with and without BRCA mutations have comparable survival rates.

Cancer risk in women who work night shifts long-term

For women who work night shifts, breast cancer risks increase by 3.3% for every 5 years of work.

Skin cancer risk higher in patients with atopic dermatitis

Patients with atopic dermatitis may have a greater risk of developing squamous cell carcinoma.

Hormonal contraception use linked to an increased risk of breast cancer

Breast cancer diagnosis is higher among women who currently use or recently used contemporary hormonal contraceptives than among women who have never used hormonal contraceptives.

Nivolumab treatment for lung cancer may successfully deplete HIV reservoirs

Nivolumab treatment for non-small-cell lung cancer may induce successful depletion of HIV reservoir.

Adolescent acne not linked to malignant melanoma in men

Body mass index is linked to malignant melanoma in men.

Oxybenzone in lotion linked to dermatological, environmental toxicity

Oxybenzone, found in sunscreens and other products, has harmful dermatological and environmental effects.

FDA approves new hemophilia A drug with factor VIII inhibitors

New FDA-approved prophylactic treatment decreases bleeding episodes hemophilia A patients with factor VIII inhibitors.

ASCO: Alcohol consumption increases cancer risk

According to a special report by the American Society of Clinical Oncology, alcohol consumption is a definite risk for cancer development.

Overweight, obesity-related cancers increasing in the United States

Incidence rates of overweight- and obesity-related cancers have increased in the United States.

Vitamin D supplementation not associated with reduced cancer risk

Little evidence was found for linear causal associations between genetic determinants of circulating vitamin D concentration and risk of seven cancers.

Warfarin associated with lower cancer risk in older adults

Warfarin use may provide cancer protection across a broad range of malignant neoplasms.

AJCC melanoma staging system is revised

American Joint Commtitee on Cancer melamona staging system revised.

USPSTF recommends skin cancer prevention care to begin at age 6 months

The USPSTF has released updated recommendations on skin cancer counseling and self-examination for adults with fair skin.

Gastroesophageal adenocarcinoma patients benefit from adjuvant chemotherapy

The researchers found that patients receiving adjuvant chemotherapy for gastroesophageal adenocarcinoma were younger, more likely to have advanced disease, and had shorter postoperative inpatient stays.

Increased cancer risk found in rheumatoid arthritis patients with VTE

VTE and cancer are the result of inflammation and immunological dysfunctions associated with RA.

Pediatric inflammatory bowel disease increases cancer risk in adulthood

Patients with childhood-onset IBD have an increased risk of cancer, especially gastrointestinal cancers, lymphoid neoplasms, and skin cancer,

Cervical cancer screening: recommendations from the USPSTF

The major change includes screening with hrHPV testing alone as an alternative to cytology screening alone starting at age 30 years.

Non-hormone options available for estrogen depletion after breast cancer

A variety of non-hormone options and therapies are available for treatment of estrogen-depletion symptoms and clinical problems after a diagnosis of breast cancer.

Annual mammography from age 40 decreases breast cancer mortality

Thousands of US lives would be saved each year if women received annual mammograms starting at age 40.

Vitamin B supplements not chemopreventive for lung cancer

Vitamin B supplements are not chemopreventive and may increase cancer risk in men.

Antiemetics: a clinical practice guideline update from ASCO

The updated guidelines will help clinicians prevent and manage nausea and vomiting caused by antineoplastic agents or radiation therapy in cancer patients.

Consuming total, saturated fat increases the risk of lung cancer

The risk of lung cancer was reduced for high intake of polyunsaturated fat.

Ovarian cancer screening: a USPSTF recommendation statement

The USPSTF states that the harms of screening for ovarian cancer in asymptomatic women outweigh the benefits.

Surgery may not improve outcomes in early-stage prostate cancer

A 20-year study found that patients with early-stage prostate cancer who have surgery to remove their tumor do not live longer than those who receive no treatment.

Breast, ovarian cancer risks estimated for BRCA1/BRCA2 mutation carriers

Breast cancer risk is increased with a larger number of first- and second-degree relatives diagnosed as having breast cancer for both BRCA1/BRCA2 carriers.

Mammogram referral, screening rates boosted with point-of-care screening program

A breast cancer screening program helped improve mammography referral and screening rates in a federally qualified health center.

ASCO: Capecitabine may prolong survival in patients with biliary tract cancer

The researchers found that the average survival after surgery for those receiving capecitabine was longer compared with those who only had surgery.

One alcoholic drink per day may increase breast cancer risk

Drinking the equivalent of a small glass of wine or beer a day increases pre-menopausal breast cancer risk by 5% and post-menopausal breast cancer risk by 9%.

Nitrate inhalants (poppers) associated with increased virus-associated cancer risk in HIV-uninfected MSM

Among HIV-uninfected men aged 50 to 70, heavy popper use was associated with an increased risk of virus-associated cancer with causes linked to HPV, HHV-8, and Epstein-Barr virus.

Low-dose aspirin reduces breast cancer risk

Developing breast cancer was associated inversely with taking 3 or more tablets of low-dose aspirin per week.

Integrative therapies during and after breast cancer treatment: a clinical practice guideline

Evidence supports the routine use of mind-body practices, such as yoga, meditation, relaxation techniques, and passive music therapy, to address common mental health concerns in patients with breast cancer.

Metastatic pancreatic cancer: a new clinical practice guideline

The guideline will help clinicians determine the appropriate treatment of patients with metastatic pancreatic cancer.

USPSTF recommends individualized approach to prostate cancer screening

The USPSTF recommends that prostate cancer screenings should be an individual decision.

Vitamin D and calcium supplementation not effective for lowering cancer risk in postmenopausal women

Vitamin D and calcium did not result in a significantly lower risk of all-type cancer, including breast cancer, in postmenopausal women.

Colorectal cancer characteristics different, outcomes worse among octogenarians

Octogenarians with colorectal cancer have several differences in clinical and tumor characteristics, compared with younger patients with the disease.

Lithium not linked to increased cancer risk in patients with bipolar disorder

No difference was observed in risk of overall cancer in patients with bipolar disorder who use lithium, compared with the general population.

Additional weight may affect risk of gastrointestinal cancers

Excess weight could influence the risk of of gastrointestinal cancers by altering insulin levels and promoting inflammation.

Antiandrogen therapy improves long-term survival after prostate cancer returns

Antiandrogen therapy with daily bicalutamide to salvage radiation therapy resulted in significantly higher rates of long-term overall survival.

VA lung cancer screening program finds high rate of incidental findings, low cancer detection rate

An estimated 900,000 veterans of a population of 6.7 million VHA patients met the criteria for LCS.

Recommendations released for management of small renal masses

Researchers used data from 83 studies to develop guideline for management of patients with small renal masses.

Is vasectomy linked to risk of prostate cancer?

Vasectomy can continue to be a safe method of contraception in men.

Cancer-related deaths attributed to smoking vary across states

Cancer deaths attributed to cigarette smoking are common among the Southern states.

Abnormal uterine bleeding linked to hematologic malignancies

Women presenting with new-onset heavy menstrual bleeding plus thrombocytopenia or pancytopenia should be evaulatued for a possible hematologic malignancy.

ASCO issues guidelines for chronic pain in patients with a history of adult cancer

Screening for pain at every visit is recommended, and management and treatment options are specified.

Alcohol consumption, obesity raise risk of esophageal cancer

One-third of cases may be avoided if patients maintained a healthy weight and limited alcohol consumption.

Acupressure effective for fatigue linked to breast cancer

Nearly 70% of participants who self-administered acupressure therapy experienced improved levels of fatigue.

Direct-acting antivirals in hepatitis C do not reduce hepatocellular carcinoma occurrence

Patients previously treated for HCC have a high risk of tumor recurrence in the long term.

USPSTF recommends screening for colorectal cancer from age 50 to 75

The USPSTF has released a recommendation statement regarding screening adults for colorectal cancer.

Long-term breast cancer care transitioning to primary care clinicians

As breast cancer survivorship increases, NPs have taken on long-term patient care.

Interventions effectively increase colon cancer screening rates

Multi-level interventions can effectively increase rates of colon cancer screening in a primary care setting.

Routine primary care screening improves detection of melanomas

Primary care screening can help patients avoid the need for more aggressive therapy and potentially save lives.

Additional adjuvant aromatase inhibitor therapy improves breast cancer outcomes

Extending adjuvant aromatase inhibitor treatment can decrease disease recurrence and increase survival in breast cancer patients.

ASCO releases clinical practice guideline for pancreatic cancer

A clinical practice guideline offers recommendations on the best course of treatment for patients with potentially treatable pancreatic cancer.

Fruit consumption linked to lower breast cancer risk

Fruit intake in adolescence may be associated with decreased breast cancer rates in adulthood.

Additional treatment not effective to treat pancreatic cancer

Median overall survival was 11.9 months in patients receiving gemcitabine plus erlotinib.

Tumor recurrence is common in patients with hepatitis C, hepatocellular carcinoma

Direct-acting antivirals pose challenges in patients with hepatitis C and prior hepatocellular carcinoma

Cancer may complicate HIV management

The rates of many cancers increase in in HIV positive individuals.

Digital mammography plus tomosynthesis linked to increased rate of breast cancer diagnosis

The combination of tomosynthesis and digital mammography screening may benefit women with heterogeneously dense breasts.

Increased use of Gardasil 9 for HPV prevention would reduce cervical cancer rates, healthcare costs

The new vaccine protects against 9 types of HPV and 5 cancer-causing strains.

Women advised to undergo breast cancer risk assessment at 40

50% of women studied met the American Cancer Society requirements for early mammography screening.

ASCO recommendations aim to increase HPV vaccination rates

The American Society of Clinical Oncology has released its recommendations to help improve rates of HPV vaccination worldwide.

Low-dose aspirin regimen may reduce risk of certain cancers

A low-dose aspirin regimen was associated with a 3% lower risk of cancer overall.

How effective is aggressive end-of-life cancer care?

Families of patients who receive aggressive end-of-life medical care do not perceive the care as high-quality.

Hematuria evaluation guidelines issued by ACP

The ACP has released clinical guidelines for the evaluation of hematuria and referral practices.

Colorectal cancer diagnoses increase in patients younger than age 50

Nearly 15% of colorectal cancer patients were diagnosed before age 50.

USPSTF issues final updated mammography screening guidelines

In an update to its 2009 recommendations, the U.S. Preventive Services Task Force has presented its final guidelines on mammography screening for breast cancer.

Blood test may improve advanced melanoma tracking

A new blood test assesses levels of circulating tumor DNA (ctDNA) in patients with unresectable stage IIIC/IV melanoma.

Diagnostic factors help patients avoid confirmatory prostate biopsy

The analysis of diagnostic characteristics may predict the result of a confirmatory biopsy.

False-positive mammograms and breast cancer risk

False-positive results on a screening mammogram are associated with a greater risk of developing breast cancer in the 10 years following the result.

Evidence lacking to assess benefits/harm of visual skin cancer screening

The USPTF has determined that there is insufficient evidence for the harms and benefits of visual skin cancer screening.

Guidelines for hematologic malignancies in pregnancy

New guidelines have been developed for the diagnosis and treatment of hematologic malignancies during pregnancy.

Prostate cancer treatment linked to Alzheimer's risk

Patients treated with androgen deprivation therapy had a 1.88-times increased rate of developing Alzheimer's disease.

Ultrasound, mammograms have similar breast cancer detection rates

A new study of women with at least 2 risk factors for breast cancer found that ultrasound and mammography have similar breast cancer detection rates.

Periodontal disease associated with elevated breast cancer risk

Postmenopausal women especially former smokers who quit within the last 20 years have an increased risk of postmenopausal breast cancer associated with periodontal disease.

African American women least likely to benefit from neoadjuvant breast cancer treatment

In a study of over 278,000 patients with stage 1 through stage 3 breast cancer, African American women had the lowest rate of pathologic complete response.

Active surveillance of low-risk prostate cancer patients may not be efficient

New research suggests that men with low-risk prostate cancer who undergo choose watchful waiting may not receive timely treatment when compared to those undergoing active treatment.

Reduction in number of men screened for and diagnosed with prostate cancer

In the United States, the rate of prostate cancer screening is down, and the number of men diagnosed with the disease has also dropped.

Mammography without CAD

Digital screening mammography is as accurate without computer-aided detection (CAD) as it is with the technology.

Breast cancer incidence is nearly identical in black and white women

Data released by the American Cancer Society show that, for the first time, breast cancer incidence is nearly identical in black and white women.

Processed meats cause colorectal cancer in humans, according to WHO

A report from WHO found that processed meat causes colorectal cancer, and red meat is positively associated with several cancers.

New guidelines recommend mammograms in women beginning at age 45

New guidelines from the American Cancer Society suggest that to combat overdiagnosis, women begin mammography screening for breast cancer at age 45 and continue yearly through age 54 before transitioning to a biannual screening plan.

Increased life span of HIV patients increases certain cancer risks

As HIV patients are living longer, their risk of developing anal, liver, and colorectal cancer is increasing.

Colorectal cancer screening recommended for patients aged 50 to 75 years

Adults aged 50 to 75 years should be screened for colorectal cancer. For older adults, the decision to screen should be based on the individual.

Few women receive genetic counseling prior to BRCA test

Women who receive genetic counseling prior to undergoing BRCA testing display more knowledge of both the testing process and of the potential results.

Active surveillance 
encouraged for prostate cancer screening

Men should regularly be screened for prostate cancer, the leading cause of cancer death for men in the United States.

Childhood cancer, stroke survivors at risk for second stroke

According to a study published in Neurology, people who survived cancer and stroke in childhood have a doubled risk of a second stroke.

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