Hepatitis

FDA: Chocolates, Candies May Be Contaminated With Hepatitis A

FDA: Chocolates, Candies May Be Contaminated With Hepatitis A

Worker at Bauer's Candies facility in Kentucky tested positive for hepatitis A.

USPSTF Affirms Guidance for Hep B Screening at First Prenatal Visit

USPSTF Affirms Guidance for Hep B Screening at First Prenatal Visit

Evidence convincing that universal prenatal screening reduces perinatal transmission of HBV.

Updated Recommendations, Hepatitis A Vaccine Postexposure Prophylaxis and Travel

Updated Recommendations, Hepatitis A Vaccine Postexposure Prophylaxis and Travel

The Advisory Committee on Immunization Practices Hepatitis Vaccines Work Group has updated recommendations for hepatitis A vaccination for PEP and PrEP.

Survival Similar With Donor Hearts From Hepatitis C+ Donors

Survival Similar With Donor Hearts From Hepatitis C+ Donors

Second study shows no significant difference in patients' survival based on donor BMI.

New Four-Drug Regimen Effective in Patients With HCV Who Inject Drugs

New Four-Drug Regimen Effective in Patients With HCV Who Inject Drugs

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Those with HCV genotype 1 with recent injection drug use and/or current opioid substitution therapy, paritaprevir/ritonavir, ombitasvir, and dasabuvir with/without ribavirin is effective.

Glecaprevir and Pibrentasvir Improve Extrahepatic Manifestations in Hepatitis C

Glecaprevir and Pibrentasvir Improve Extrahepatic Manifestations in Hepatitis C

Patients with chronic HCV undergoing short-term glecaprevir and pibrentasvir treatment show improved cardiovascular and metabolic extrahepatic manifestations.

Targeted HCV Testing Misses High Number of Cases in Prisons

Targeted HCV Testing Misses High Number of Cases in Prisons

Findings based on birth cohort, risk-based testing vs opt-out testing in prison system.

Suboptimal Rates of Adherence to Chronic HBV Treatment Guidelines Identified

Suboptimal Rates of Adherence to Chronic HBV Treatment Guidelines Identified

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Adherence to the American Association for the Study of Liver Diseases criteria for evaluation and treatment of chronic HBV infection was found to be poor in all practice settings assessed.

High Prevalence of Cirrhosis in Adults With Chronic HBV at a Safety-Net Hospital

High Prevalence of Cirrhosis in Adults With Chronic HBV at a Safety-Net Hospital

Investigators aimed to determine rates and predictors of cirrhosis and cirrhosis-related complications in patients with chronic hepatitis B infection.

Universal vs Risk-Based Screening in Pregnancy: An Expert Weighs In

Universal vs Risk-Based Screening in Pregnancy: An Expert Weighs In

There is a lack of consensus among experts and professional organizations whether HCV screening in pregnant women should be risk based or universal.

Over 2 Million People Living With HCV From 2013 to 2016

Over 2 Million People Living With HCV From 2013 to 2016

Overall, 1.7 and 1.0% of all US adults HCV antibody-positive and HCV RNA-positive.

Direct-Acting Agents Help to Eliminate Hepatitis C in Liver Transplant Recipients

Direct-Acting Agents Help to Eliminate Hepatitis C in Liver Transplant Recipients

The introduction of DAAs has caused a significant reduction in the percentage of liver transplant recipients for HCV who are viremic after surgery.

One-Time, Universal Screening for Hepatitis C Is Cost-Effective

One-Time, Universal Screening for Hepatitis C Is Cost-Effective

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Universal 1-time screening for chronic HCV infection is cost-effective compared with no screening or with birth cohort-based screening alone.

Updated HCV Treatment Guidelines for 2018 Published by AASLD-IDSA

Updated HCV Treatment Guidelines for 2018 Published by AASLD-IDSA

The American Association for the Study of Liver Diseases (AASLD) and the Infectious Diseases Society of America (IDSA) released updates guidelines for treating hepatitis C infection.

Rituximab Linked to HBV Reactivation in Patients With Prior Functional Cure

Rituximab Linked to HBV Reactivation in Patients With Prior Functional Cure

The study authors searched MEDLINE from inception through July 2018 to obtain relevant cohort studies and randomized trials assessing HBVr incidence secondary to pharmaceutical agents.

Need for Adequate Screening for Infants With HCV Infected Mothers During Pregnancy

Need for Adequate Screening for Infants With HCV Infected Mothers During Pregnancy

One of the goals of the US Department of Health and Human Services National Viral Hepatitis Action Plan is to eliminate mother-to-infant transmission of HCV infection.

Sofosbuvir-Based Regimens Safe, Effective for Chronic Hepatitis C in the Community

Sofosbuvir-Based Regimens Safe, Effective for Chronic Hepatitis C in the Community

Investigators examined treatment response of sofosbuvir-based DAA in patients with chronic hepatitis C with compensated liver cirrhosis in a community care setting.

Glecaprevir/Pibrentasvir Is Safe, Efficacious for HCV/HIV-1 Coinfection

Glecaprevir/Pibrentasvir Is Safe, Efficacious for HCV/HIV-1 Coinfection

Analysis of 2 phase 3 clinical trials evaluating the safety/efficacy of glecaprevir/pibrentasvir in people with HCV coinfected with HIV-1 found an overall sustained virologic response of 98% at week 12 of treatment in those with or without cirrhosis.

First Human Case of Rat Strain of Hepatitis E Found

First Human Case of Rat Strain of Hepatitis E Found

The first human case of a strain of hepatitis E previously found only in rats was diagnosed in a Hong Kong man who received a liver transplant in May 2017.

Patrons of 'Vampire Facial' Spa May Have Been Exposed to HIV

Patrons of 'Vampire Facial' Spa May Have Been Exposed to HIV

Inspection at the VIP Spa in Albuquerque detected practices that might spread HIV or hepatitis B and C.

HCV DAA Curative Therapy Associated With Liver Fibrosis Regression

HCV DAA Curative Therapy Associated With Liver Fibrosis Regression

Curing HCV infection with direct-acting antiretrovirals is associated with regression of liver fibrosis for most patients.

Factors Associated With Faster Time to Hepatitis C Treatment

Factors Associated With Faster Time to Hepatitis C Treatment

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The researchers found a significant difference in mean time to direct-acting antiviral agent treatment among participants with public insurance payers compared with private insurance payers.

HCV Neuropsychiatric Symptoms Likely Linked to Virus' Effects on Brain Function

HCV Neuropsychiatric Symptoms Likely Linked to Virus' Effects on Brain Function

The neuropsychiatric symptoms associated with HCV infection are likely caused by the body's response to the virus' effects on brain function.

HBV Antibody Persistence in Adolescents Vaccinated With DTPa-HBV-IPV/Hib as Infants

HBV Antibody Persistence in Adolescents Vaccinated With DTPa-HBV-IPV/Hib as Infants

A robust anamnestic response was mounted in most adolescents when challenged with a dose of monovalent HBV vaccine.

Real-World Efficacy of DAAs in African Americans With Chronic HCV GT-1 Infection

Real-World Efficacy of DAAs in African Americans With Chronic HCV GT-1 Infection

Direct-acting antivirals are safe and effective in African-American patients with chronic HCV.

Toward Integrated Care for Hepatitis C Infection and Addiction

Toward Integrated Care for Hepatitis C Infection and Addiction

There is an opportunity to improve HCV treatment rates for people who inject drugs by integrating DAA therapy into current models of community-based addiction.

Good Outcomes for HCV-Negative Recipients of HCV Kidneys

Good Outcomes for HCV-Negative Recipients of HCV Kidneys

All 20 recipients experienced HCV cure, good quality of life, excellent renal function.

Availability of Generic Antivirals for Hepatitis B Increasing

Availability of Generic Antivirals for Hepatitis B Increasing

Drop in median price of WHO-prequalified generic tenofovir from 208 to 32 from 2004 to 2016

Successful Screening and Referral for HIV, Hepatitis C in a Trauma Population

Successful Screening and Referral for HIV, Hepatitis C in a Trauma Population

Investigators added hepatitis C virus and HIV screening tests to standard trauma activation laboratory orders.

Coordinated Care Enhances Access to Hepatitis C Antiviral Treatment

Coordinated Care Enhances Access to Hepatitis C Antiviral Treatment

Coordinated treatment programs may improve treatment outcomes in patients with hepatitis C infection.

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