HIV/AIDS Information Center Archive

Nivolumab treatment for lung cancer may successfully deplete HIV reservoirs

Nivolumab treatment for non-small-cell lung cancer may induce successful depletion of HIV reservoir.

HIV occurrences decline in Uganda from 1999 to 2016

The decrease in HIV incidence in Uganda was facilitated by antiretroviral therapy, male circumcision, and adolescent abstinence.

Characteristics in transgender individuals may lead to more HIV tests

More tests might be administered to transgender individuals who are female, black, or sex workers.

Dual HIV treatment provides simple, safe salvage regimen

The dual combination of dolutegravir plus darunavir/ritonavir provided a simple and safe salvage therapy to suppress viral replication without metabolic impact in patients infected with HIV-1.

Hepatitis increases mortality rates in HIV patients

Hepatitis B and hepatitis C may increase mortality risks in HIV patients.

Law upheld requiring HIV-infected adults to tell sexual partners of their status

The Ohio Supreme Court has unanimously upheld the constitutionality of a law requiring HIV-infected individuals to tell their sexual partners of their illness.

CDC updates contraception recommendations for women at risk for HIV

The CDC revised its US Medical Eligibility Criteria for Contraceptive Use categorization for DMPA injection in women at high risk for HIV infection from US MEC category 1 to US MEC category 2.

Antiretroviral therapy resistance increasing in HIV treatment

Resistance to ART is threatening the recent gains of treatment in the rate of new HIV infections.

High percentage of HIV-diagnosed women not receiving care

More than half of women receiving a new HIV diagnosis have already received this diagnosis in the past but are not undergoing HIV medical care.

HIV care outcomes low for Hispanics and Latinos

Infection was diagnosed at an early stage for fewer males with infection attributed to heterosexual contact vs male-to-male sexual contact.

Chronic pain management in HIV: Updated recommendations

The HIV Medicine Association of the Infectious Disease Society of America recommends that people living with HIV be screened for pain and offered both nonpharmacologic and pharmacologic treatment options.

Single-tablet HIV treatment superior to standard therapy

Virological response, efficacy, noninferiority, and tolerability were tested for bictegravir, emtricitabine, and tenofovir alafenamide in patients with HIV.

Notification rates of HIV diagnoses increased in 16 European countries

In 16 countries, notification rates for new HIV diagnoses in older adults increased significantly, clustering in central and eastern European countries.

Once-daily HIV tablet safe for children

Elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide was well tolerated in children and maintained high virological suppression.

Vitamin D supplements may improve bone health in HIV-infected youth

High-dose vitamin D supplements improve bone mineral density in youth with HIV.

Clinical practice guideline for antiretroviral therapy in pregnant women with HIV

Alternative treatments should be offered to pregnant women with HIV instead of tenofovir or emtricitabine.

Smartphone-based electronic reader reliable for point-of-care tests in HIV and T pallidum infections

The findings shed new light on the applicability of smartphone-based electronic readers in point-of-care testing.

PrEP adherence in adolescent MSM decreases over time

Adherence decreased over time in adolescent MSM who participated in a 48-week HIV PrEP intervention.

Sexually risky behavior more common in women with mental disorders than in men

Women with mental illness engage in significantly more sexually risky behaviors than men, and personality risk scores are a significant predictor of total sex acts for women but not men.

Offering rapid HIV testing to patients increases overall testing rate in the emergency department

Rapid HIV testing offered in parallel to patient-clinician consultations increases the testing rate in the emergency department.

WHO releases new guidelines in response to pretreatment HIV drug resistance

The new guidelines address the issue of how to manage pretreatment HIV drug resistance in countries where the prevalence of is 10% or higher.

Child with HIV suppresses virus without antiretroviral therapy for more than 8 years

A child who was diagnosed with HIV at 1 month and received early treatment has suppressed the virus without anti-HIV therapy for 8.5 years.

Injectable antiretroviral therapy for as HIV effective as oral medications

The investigators found that after 32 weeks, HIV remained suppressed in 91% percent of those taking the drugs orally, 94% of those receiving monthly injections, and 95% of patients receiving injections every two months.

Blood-borne viruses more common in patients with severe mental illness

HIV, hepatitis B, and hepatitis C infections are more common among individuals with severe mental illness.

WHO updates Essential Medicines List, recommendations for antibiotics

The update includes 30 new medicines for adults and 25 for children and groups antibiotics into 3 distinct categories.

Early antiretroviral therapy initiation linked to bone loss in HIV patients

Early antiretroviral therapy initiation may increase the rate of bone loss in HIV patients.

Walgreens expands availability of PrEP for HIV prevention

Providers in 17 new Walgreens locations will be able to prescribe PrEP for HIV prevention.

FDA approves first generic version of Truvada for HIV

The drug is indicated for use in combination with other antiretroviral agents for the treatment of pediatric and adult patients with HIV-1.

HIV testing rates low in young men who have sex with men

The CDC found that 28% of young men who have sex with men have undergone HIV testing, though they account for 83% of new diagnoses.

High HCV cure rates in patients with HIV coinfection at urban clinic

Hepatitis C treatment in HIV coinfection cases is effective with standardized nurse and pharmacist support for patients in an urban clinic.

Amphotericin B superior to itraconazole for HIV-associated talaromycosis

Treatment with amphotericin B was superior to itraconazole as an induction therapy for HIV-associated talaromycosis.

Postpartum antiretroviral therapy is beneficial in HIV-positive women

Continued antiretroviral therapy was found to be safe and beneficial in HIV-positive postpartum women with high CD4+ T cell counts.

A link between antiretroviral therapy and diabetes in HIV patients?

HIV-infected patients on ART had approximately 4 and 1.5 greater odds of developing diabetes mellitus and metabolic syndrome, respectively.

Quality of life in military HIV patients affected by advanced disease and mental comorbidity

Factors linked to health-related quality of life in military HIV patients include advanced HIV disease and mental or medical comorbidity.

Conception methods available for reducing risk of transmission in HIV-discordant couples

Strategies are available to reduce the risk of HIV transmission using sperm from HIV-infected male.

HIV/AIDS epidemic could end by 2025 in the United States

Researchers predict that the infection rate could be as low as 12,000 people a year by 2025.

Nitrate inhalants (poppers) associated with increased virus-associated cancer risk in HIV-uninfected MSM

Among HIV-uninfected men aged 50 to 70, heavy popper use was associated with an increased risk of virus-associated cancer with causes linked to HPV, HHV-8, and Epstein-Barr virus.

Warfarin dosing in HIV patients with deep venous thrombosis

Results showed that mean induction times, analyzed in 170 patients, were 12.87 days in the HIV-infected patients and 11.19 days in the HIV-uninfected patients.

FDA approves label changes for two HIV drugs

The FDA Drug Interactions section has been updated to include revised information on concomitant use of corticosteroids with these drugs.

Side effects may affect medication nonadherence in patients with chronic disease

Almost half of participants reported that they never received information regarding the side effects of their medication from their prescriber.

Trained lay healthcare providers can administer HIV testing

A World Health Organization expert panel recommended lay health care workers be allowed to conduct HIV testing services using rapid diagnostic tests.

Annual rate of perinatal HIV infection decreased in United States

However, missed opportunities for prevention were common among infected infants and their mothers in recent years.

Mortality rates remain high among HIV-positive patients

The HIV-positive population of the United Kingdom has a higher risk of death than the general population, despite availability of free treatment and care.

VA offers hepatitis, HIV screening to veterans who received improper dental care

A VA center in Wisconsin is advising veterans to be screened for hepatitis and HIV after receiving care from a dentist who did not follow VA procedures.

New clinical trial underway to study efficacy of HIV vaccine

The study will be the largest HIV vaccine clinical trial to take place in South Africa.

Mortality rate from infectious diseases remains unchanged in the United States

The number of patients dying from infections has remained stable, but some disease threats have changed.

Antenatal antiretroviral therapy reduces early HIV transmission

Antenatal ART reduces rates of early HIV transmission but may increase risk of adverse maternal and neonatal outcomes.

Smoking more harmful for HIV patients than the virus

Men and women who quit smoking after entering HIV care at age 40 years gained 5.7 years and 4.6 years of life expectancy, respectively, compared with those who continued to smoke.

CDC presents updated recommendations for meningococcal vaccine in HIV

HIV-infected individuals should receive the meningococcal conjugate vaccine (serogroups A, C, W, and Y).

HIV's newly traced origins in US discredit Patient Zero theory

The study debunks the theory that Patient Zero was responsible for the AIDS epidemic in North America.

Increasing recruitment to meet demand for HIV care providers

Speakers at IDWeek 2016 addressed the demand for additional HIV care providers.

DMPA contraceptives linked to increased HIV risk

Recent data suggest that use of depot medroxyprogesterone acetate may increase women's HIV acquisition risk.

HBV and HCV coinfection increases non-Hodgkin risk in ART-treated HIV

Patients with HIV receiving antiretroviral treatment have a higher risk of non-Hodgkin's lymphoma with HBV and HCV coinfection.

Many patients with HIV have a successful response to ART

Treatment with 3 medications compared with 4 or more correlated with immune success at the end of follow-up.

Lack of epidemiologic indicators increases risk of missed HIV diagnosis

The results of a multicenter, cross-sectional study showed that 37% of patients could have been diagnosed with HIV at an earlier stage.

Comparing first-line antiretroviral therapies for HIV

The efficacy and safety of ART have greatly improved with the newer drug classes of antiretrovirals.

Increased HIV testing linked to earlier diagnosis in men who have sex with men

Researchers analyzed data from 21 jurisdictions conducting HIV incidence surveillance from 2007 to 2013.

Immediate antiretroviral therapy may reduce infection-related cancer in HIV

Patients with HIV infection with immediate access to antiretroviral therapy may have a reduced risk of infection-related cancer.

Efficacy of distributing HIV self-tests via Grindr

Free self-test kits were advertised among a population of high-risk MSM.

Early ART lowers risk of HIV-1 infection among sexual partners

Researchers observed 78 HIV-1 among partners, with an annual incidence of 0.9%.

Injectable oxymorphone, syringe sharing lead to HIV outbreak

The use of injectable, extended-release oxymorphone and syringe sharing was linked to an outbreak of HIV infections in Indiana.

HIV viral load linked to liver fibrosis

Patients with HIV infection and elevated viral load are likely to progress to advanced hepatic fibrosis.

Perinatal HIV exposure has negative psychosocial consequences

Children who were perinatally exposed to HIV are more likely to struggle with psychosocial adjustment during childhood and adolescence.

Pregnant women with HIV retained in care

Many women were found to have poor postpartum virologic control.

Posthysterectomy Pap testing may benefit women with HIV

More than 30% of women with HIV and no prehysterectomy had abnormal Pap test results.

HIV, STI rates elevated among young MSM

The relationship between HIV and STI rates and race/ethnicity and partner characteristics should be considered in future HIV intervention.

ART may not reduce HIV-associated arterial inflammation

Antiretroviral therapy in HIV-positive patients did not decrease the progression of arterial inflammation.

COPD screening needed in HIV-positive patients

Many HIV-positive patients who meet the criteria for COPD are not receiving proper treatment.

Signs and symptoms not present during acute HIV-1 infection

Signs and symptoms are not typically observed during acute HIV-1 infection.

Shared decision making aids medication management

Researchers found that shared decision making is effective when managing medication therapy in patients.

Abstinence, fidelity programs are ineffective for HIV prevention

A study has found no evidence that programs promoting abstinence can reduce risky sexual behaviors that can increase the risk of HIV.

HIV infection, transmission rates decrease

Instances of new HIV infections decreased by 11%.

Cancer may complicate HIV management

The rates of many cancers increase in in HIV positive individuals.

HIV treatments, immunosuppressants may interact in transplant patients

A renal transplant recipient experienced drug interaction-induced calcineurin inhibitor nephrotoxicity after starting a cobicistat-containing combination treatment for HIV.

Text message alerts can improve appointment adherence for patients with HIV

Patients with HIV have an increased risk of clinical nonadherence, which can be improved with text message alerts.

Antiretroviral therapy during pregnancy may increase risk of preterm birth

Pregnant women with HIV who undergo antiretroviral therapy may have an increased risk of preterm birth, low birth weight, and small-for-gestational age infants.

HCV, HIV co-infection linked to increased diabetes risk

Treatment guidelines must expand to focus on patients co-infected with both HCV and HIV.

Sustained virological response found at 5 years in low-risk patients with HCV

Patients with HCV/HIV coinfections had a much higher risk of HCV recurrence.

Limited data on molluscum contagiosum treatment in HIV

Overall quality of the studies reviewed was poor, leaving gaps in the development treatment recommendations for MC.

Male adolescents with HIV have high rates of inflammation, bone loss

HIV-infected male adolescents present with elevated rates of bone loss due to immune dysregulation, chronic inflammation, and antiretroviral therapy.

Truvada approved for pediatric HIV-1 treatment

Gilead Sciences has received approval to indicate Truvada for pediatric patients with HIV-1.

Sexual identity disclosure linked to elevated rates of HIV testing, hepatitis vaccinations

Men who have sex with men who disclosed their sexual identity to their providers were more likely to receive appropriate health services, including routine HIV testing and hepatitis vaccinations.

FDA approves Odefsey for HIV-1 treatment

Odefsey combines emtricitabine and tenofovir alafenamide with rilpivirine to treat HIV-1.

WHO guideline poised to reduce HIV-related deaths

Rapid initiation of antiretroviral therapy will likely reduce the number of HIV-related deaths.

Vaginal ring decreases incidence of HIV-1 infection

HIV-1 incidence was reduced by 27% among all study participants.

Opt-out testing may increase HIV screening rates

More than 65% of patients in the "opt-out" group accepted the HIV test, according to researchers.

HIV testing rates low among young adults, teens, according to CDC report

High school aged males were less likely to have been tested than females.

Taking PrEP before and after sex reduces HIV risk for MSM

Men who have sex with men can reduce their risk of contracting HIV by taking PrEP before and after sex instead of every day.

HIV prophylaxis can prevent transmission to breastfeeding infants

Breastfeeding mothers who are HIV-positive can prevent transmission to their infants through a lopinavir-ritonavir or lamivudine regimen.

AAP guidelines recommend screening children for high cholesterol, depression, HIV

To combat the stigma associated with selective screening, the American Academy of Pediatrics has called for all children to be screened for high cholesterol, depression, and HIV.

More people at risk for HIV need PrEP prescriptions, says CDC

The CDC said that too few Americans who have an increased risk for HIV are taking the PrEP pill to help protect them against HIV.

Ahead of violent conflict, HIV transmission is high

The study tracked HIV incidence statistics in 36 sub-Saharan countries from 1990 through 2012 and correlated them with periods of conflict and peace in each country.

Pre-exposure prophylaxis for HIV effective for transgender women

Researchers at the University of California, San Francisco, have found that pre-exposure prophylaxis can be effective in preventing HIV in transgender women when used consistently.

Engineered DART molecules target HIV-infected cells to eliminate viral reservoirs

Molecules engineered to target killer T cells and HIV-infected cells can reduce detectable HIV expression in HIV-positive patients.

Genvoya approved to treat HIV-1 infection

Genvoya, a tablet containing a new form of tenofovir, is now FDA-approved to treat HIV-1 infection in adults and children.

Multidisciplinary team launches new HIV vaccine initiative

Scientists from 22 institutions are launching a new research initiative with the goal of taking a new HIV vaccine through human trials in the next 5 years.

Statins slow progression of liver disease in patients with HIV, Hep C

Statin use in co-infected patients showed a slowed progression of liver disease, according to a study conducted at the Johns Hopkins Moore Clinic for HIV Care.

Antiretroviral therapy recommended for all HIV patients, says WHO

The World Health Organization is seeking to remove all limitations on eligibility for antiretroviral therapy for HIV patients in an effort to encourage treatment as soon after diagnosis as possible.

HIV patient care improved by Affordable Care Act

Low-income HIV patients are faring better under the Affordable Care Act than they did on traditional state assistance.

Increased life span of HIV patients increases certain cancer risks

As HIV patients are living longer, their risk of developing anal, liver, and colorectal cancer is increasing.

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