Pam was a 54-year-old woman who had recently been diagnosed with endometrial and ovarian cancer. She had surgery and then underwent radiation and chemotherapy treatments. Approximately 2 months after she had finished her chemotherapy, she noticed annoying, mild-to-moderate arthralgias. Her oncologist explained to her that this was a fairly common phenomenon. The literature suggests that early treatment with NSAIDS is usually effective and that the condition usually resolves. In a small percentage of patients, this pain continues for years. It appears to be more common in certain kinds of cancers, including breast cancer, ovarian cancer, and non-Hodgkin’s lymphoma. Pam’s condition gradually resolved over the next few months. The exact etiology of this syndrome is not well-understood. It does not appear to be inflammatory or immune-based. 


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