Consider changing to the Metformin XR formulation with once daily dosing for patients who find it difficult to remember to take the Metformin SR formulation twice daily. I have had several patients who experienced improved A1c and better glycemic control by taking Metformin XR 2 g once daily at a time they can remember every day, rather than taking Metformin SR 1 g twice daily, often only remembering one dose.—JEN GRENELL, APRN, CNP, Rochester, Minn. (205-4)
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