Some people experience localized skin irritation when using the transdermal fentanyl patch. To prevent this, instruct the patient to use one squirt of fluticasone (Flonase) nasal spray to the skin and let the area dry completely before applying the patch. Of course, this is considered an off-label use of fluticasone. — Leah Wood, FNP-BC, MSN, Lewisville, Tex. (151-9)

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