When explaining atherosclerosis to my patients, I compare plumbing in a new house versus the plumbing in an older house. The concept of “build up” in pipes brings clarity and, ultimately, buy-in for improved adherence to cholesterol-lowering agents. — Maricela Lara-Nevarez, PharmD, RPh, Coppell, Tex. (164-5)

These are letters from practitioners around the country who want to share their clinical problems and successes, observations and pearls with their colleagues. We invite you to participate. If you have a clinical pearl, submit it here.