Diclegis is the only FDA-approved prescription medication for nausea and vomiting of pregnancy that is classified as Category A (safe for mom an baby). Before writing a prescription, consider the price tag. Diclegis with a coupon costs approximately $345 for 60 tablets. The most common dosage is 2 tablets/d but can be more. Some patients may obtain insurance coverage for this medication, but it will likely still cost something. Let’s break down Diclegis into its 2 active ingredients: doxylamine succinate and pyridoxine hydrochloride (vitamin B6). Unless you are writing a prescription for a celebrity, recommend that your patients purchase instead over-the-counter doxylamine succinate and vitamin B6 to take at night for nausea. — Amber Murphy, PA-C, Birmingham, Michigan