Do prostate biopsies spread cancerous cells?—OSCAR RAMIREZ, NP, Valley Park, Mo.

Transrectal ultrasound–guided biopsy of the prostate is generally without complications, provided adequate antibiotic prophylaxis is given prior to the procedure. Seeding of cancerous cells is a concern, but to date there have been only isolated cases. These cases are rare and are more often associated with a transperineal approach rather than a transrectal one.—CLAIRE O’CONNELL, MPH, PA-C (219-2)

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These are letters from practitioners around the country who want to share their clinical problems and successes, observations and pearls with their colleagues. We invite you to participate. If you have a clinical pearl, submit it here.