Case 1

A 50-year-old man presents with a 2-day history of fever, malaise, and erythematous skin with widespread pustules. He reports a history of psoriasis and is concerned about the recent development of skin pustules. The patient is also febrile and has an upper respiratory tract infection. Biopsy of a pustular lesion is performed.  On histopathologic examination, the lesion displays neutrophilic infiltration and psoriasiform changes of the epidermis. Laboratory testing reveals leukocytosis and an elevated erythrocyte sedimentation rate (ESR).

Can you diagnose the condition in Case 1?

A. Generalized pustular psoriasis
B. Palmoplantar pustular psoriasis
C. Annular pustular psoriasis
D. Pustular erythema multiforme


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