A 35-year-old woman reported developing redness on her neck after applying a perfume sample while on vacation. She did not recall the name of the perfume. The area had stung at first, but in a week, the redness had resolved to an irregular brown macule. She hoped the macule would go away, but when it remained after four months, she decided to seek medical care in the dermatology clinic.

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A 7-year-old boy presented with more than 10 large tan-colored macules. The child had tested below normal in intelligence but was able to function in school. He had no history of seizures. No other skin lesions were found. Bone structure appeared normal. Some of his relatives had similar macules, but the patient’s mother was not sure what additional manifestations he shared with other family members.