Company: Berlex Pharmacologic class: Estrogen + progestin Active ingredients: Estradiol 1 mg, drospirenone 0.5 mg; tabs. Indication: In women with an intact uterus: moderate-to-severe vasomotor symptoms of menopause; moderate-to-severe vulvar and vaginal atrophy associated with menopause. Pharmacology: Angeliq combines the estrogen, estradiol, with the progestin, drospirenone, to treat moderate-to-severe symptoms of menopause. If this product…
Product: Noxafil Company: Schering Pharmacologic class: Antifungal (triazole) Active ingredient: Posaconazole 40 mg/mL; oral suspension; cherry flavor. Indication: Prophylaxis against invasive Aspergillus and Candida infections, in patients at high risk due to being severely immunocompromised, such as hematopoietic stem cell transplant recipients with Graft vs. Host Disease (GVHD) or those with hematologic malignancies with prolonged…
Company: Valeant Pharmacologic class: Antiparkinson agent (MAO-B inhibitor) Active ingredient: Selegiline 1.25 mg; orally-disintegrating tabs; contains phenylalanine. Indication: Adjunct in Parkinson’s disease in patients with deteriorating response to levodopa/carbidopa. Pharmacology: Zelapar is an orally disintegrating tablet form of selegiline that disintegrates within seconds after placement on the tongue and which is then rapidly absorbed. Selegiline…
Company: Barrier Therapeutics Pharmacologic class: Topical antifungal (azole) Active ingredient: Ketoconazole 2%; topical gel (anhydrous). Indication: Topical treatment of seborrheic dermatitis in immunocompetent patients. Pharmacology: Seborrheic dermatitis is a chronic inflammatory skin disorder that is characterized by a red, itchy, scaly rash typically occurring on the face, scalp, hairline, and trunk. Ketoconazole acts by inhibiting…
Product: Duetact Company: Takeda Pharmacologic class: Antidiabetic (thiazolidinedione + sulfonylurea) Active ingredients: Pioglitazone (as HCl) 30 mg, glimepiride 2 mg; tabs. Also: Duetact 30 mg/4 mg Active ingredients: Pioglitazone (as HCl) 30 mg, glimepiride 4 mg; tabs. Indication: Adjunct to diet and exercise in type 2 diabetes in patients already on pioglitazone + a sulfonylurea,…
Company: Cephalon Pharmacologic class: Opioid analgesic Active ingredient: Fentanyl (as citrate) 100 µg, 200 µg, 400 µg, 600 µg, 800 µg; buccal tablets. Indication: Management of breakthrough pain in patients with cancer who are already receiving and who are tolerant to opioid therapy for their underlying persistent cancer pain. Opioid-tolerant patients are those taking oral…
Product: Verdeso Company: Connetics Pharmacologic class: Topical corticosteroid (low potency) Active ingredient: Desonide 0.05%; topical foam. Indication: Mild-to-moderate atopic dermatitis in patients older than 3 months of age. Pharmacology: Desonide, like other topical corticosteroids, has anti-inflammatory, antipruritic, and vasoconstrictive actions. Verdeso is a petroleum-based emulsion formulation of desonide that is dispensed as an aerosol foam.…
Product: Januvia Company: Merck Pharmacologic class: Antidiabetic (dipeptidylpeptidase-4 inhibitor) Active ingredient: Sitagliptin (as phosphate) 25 mg, 50 mg, 100 mg; tabs. Indication: Adjunct to diet and exercise in type 2 diabetes, as monotherapy or in combination with either metformin or a thiazolidinedione. Pharmacology: Incretins, such as glucagonlike peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide, are hormones…
Company: Endo Pharmacologic class: Topical anesthetic Active ingredients: Lidocaine 70 mg, tetracaine 70 mg; topical patch. Indication: Local dermal analgesia for superficial venous access and superficial dermatologic procedures (e.g., excision, electrodesiccation, shave biopsy of skin lesions). Pharmacology: Synera is a topical patch that contains a eutectic mixture of lidocaine, an amide-type local anesthetic, and tetracaine,…
Companies: Depomed and King Pharmacologic class: Antihyperglycemic (biguanide) Active ingredient: Metformin HCl 500 mg; extended-release tabs. Indication: Adjunct to diet and exercise in type 2 diabetes as monotherapy, or with a sulfonylurea or insulin. Pharmacology: Glumetza extended-release tablets are designed to deliver metformin HCl to the upper GI tract, which may reduce GI side effects…
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