A potential link between cell-phone use and brain tumors was recently discussed in the news, based on advice from the University of Pittsburgh Cancer Institute (full-text available online free of charge at: www.environmentaloncology.org/node/201, accessed August 13, 2008). The best available evidence we have identified remains a systematic review of case-control studies (Int J Oncol. 2008;32:1097-1103). This review included 10 studies of glioma, seven studies of meningioma, and nine studies of acoustic neuroma. In general there were no significant associations overall between cell-phone use and brain tumor or between cell-phone use for >10 years and brain tumor. Increased risks were found with ipsilateral cell-phone use for >10 years, a finding that may be explained by recall bias in the absence of overall increases in brain-tumor risk.