Which medications are considered safest for both mother and fetus in pregnant patients with inflammatory arthritides, such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA)?
—Lisa A. June, MD, Louisville, Ky.

Nonsteroidal anti-inflammatory drugs are safe, as well as low doses of prednisone, which does not easily cross the placenta to the fetus. Aspirin is not teratogenic but should be discontinued close to the expected delivery date because of its antiplatelet effects.
—Daniel R. Mishell Jr, MD (116-18)

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