What topical and systemic antibiotics are recommended for corneal infection caused by staphylococci or Pseudomonas?
—Param S. Fagoora, MD, Fresno, Calif.

Bacterial keratitis is most commonly caused by Pseudomonas, Streptococcus pneumoniae, Moraxella, or Staphylococcus aureus. The condition is related to trauma, contact lens use (particularly overnight lenses), burns, surgery, and immunosuppression. In uncomplicated cases, topical treatment with a fluoroquinolone (e.g., ciprofloxacin or orofloxacin) or an aminoglycoside (e.g., tobramycin) is sufficient. In complicated cases, involving, for example, the development of a corneal ulcer or an immuncompromised host, systemic treatment with the same antibiotics can be added.
—Claire Babcock O’Connell, MPH, PA-C (114-10)

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