Breakthrough pain variability has no impact on response to sublingual fentanyl tablets or placebo
Variability in baseline breakthrough pain (BTP) has no impact on the analgesic response to sublingual fentanyl tablets or placebo.
American Pain Society 2011
Tapentadol ER safe, effective analgesic in patients with hypertension
Tapentadol ER does not significantly affect blood pressure (BP) or heart rate (HR) and thus, may be used for analgesia in patients with hypertension, study results reveal.
Embeda tamper-resistant capsule design impedes opioid drug abuse
Researchers at the American Pain Society’s 30th Annual Scientific Meeting discussed data from a review of spontaneous adverse events reported with Embeda (morphine sulfate and naltrexone HCl) treatment, with a focus on events potentially related to product tampering.
Fulranumab well tolerated but no clinical benefit for chronic low back pain
Fulranumab no more efficacious than placebo for treating patients with chronic low back pain.
Fentanyl buccal tablet better for breakthrough pain than short-acting opioids
Fentanyl buccal tablet was more effective than traditional short-acting opioids for breakthrough pain in opioid-tolerant patients.
NGX-4010, Capsaicin 8% Patch, Effective for Postherpetic Neuralgia in Older Population
A capsaicin 8% patch significantly reduces pain in older patients with postherpetic neuralgia (PHN), a debilitating condition characterized by persistent pain following the healing of a herpes zoster rash.
Milnacipran Improves Pain, Other Symptoms of Fibromyalgia
Milnacipran treatment resulted in improvements in pain and global status regardless of baseline pain severity or fibromyalgia severity.
Duloxetine, pregabalin, and duloxetine + gabapentin safe for diabetic peripheral neuropathic pain
Duloxetine, pregabalin, and duloxetine + gabapentin were found to be safe and tolerable for the treatment of diabetic peripheral neuropathic pain.
Perioperative use of etoricoxib in patients undergoing total abdominal hysterectomy
Perioperative use of etoricoxib, a selective COX-2 inhibitor, in patients undergoing total abdominal hysterectomy significantly reduces both resting and elicited pain and opioid (morphine) consumption compared with placebo.
Efficacy and safety of IV tanezumab in osteoarthritis hip and knee pain
Tanezumab, a monoclonal antibody that inhibits nerve growth factor, is efficacious in treating osteoarthritis pain and may provide greater symptomatic improvement compared with placebo and naproxen.
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