Positive topline results were announced from the second pivotal phase 3 study evaluating daridorexant (Idorsia), an investigational dual orexin receptor antagonist, for the treatment of insomnia.
Heightened cognitive arousal at bedtime is linked to objective sleep disturbances and indicators of psychological hyperarousal at night and during the day.
The American College of Physicians does not recommend chloroquine or hydroxychloroquine, with or without azithromycin, as prophylaxis against or as treatment for COVID-19.
Long-term intake of added sugar and sugar-sweetened beverages is associated with higher pericardial adipose tissue, visceral adipose tissue, and subcutaneous adipose tissue volumes.
Patients with COVID-19 appear to have a heightened risk for acute ischemic stroke compared with patients with influenza.
USPSTF recommends annual low-dose computed tomography screening for people aged 50 to 80 years at high lung cancer risk due to smoking history.
Cognitively normal women have increased Alzheimer disease endophenotype, with higher β-amyloid deposition, lower glucose metabolism, and lower gray and white matter volumes.
A phase 3 trial evaluating an investigational antiviral antibody cocktail, REGN-COV2, for the prevention of COVID-19 has been initiated by Regeneron Pharmaceuticals.
Patients with inflammatory bowel disease had a similar risk for and outcomes from coronavirus disease 2019 as those in the general population.
Long-term survivors of childhood cancers with exercise intolerance may have emotional distress, less social role achievement, and worse HRQOL.