Hypertension is not a life-threatening cardiovascular event, which may be why your advice to reduce salt intake often makes little impression. But patients’ ears will perk up when you tell them this: New research shows that reducing dietary sodium can lower the chances of an MI or stroke by 25% or more.

Investigators at Harvard Medical School in Boston, the NIH, and a number of other centers contacted 2,415 people (or their relatives) who had completed two trials 10-15 years ago that analyzed the impact of salt reduction on hypertension. People in both trials, which lasted 18-48 months, had been randomized to either their usual diets or to a 25%-35% reduction in sodium. Sodium intake was determined by repeated assessments of 24-hour urinary excretion, an unusually rigorous methodology.

In their follow-up, conducted by phone or mail, researchers determined that 200 trial participants had experienced a cardiovascular event—an MI, stroke, coronary bypass, angioplasty, or death from a cardiovascular cause. The risk of such an event was 25% lower among those in the salt-reduction groups after adjusting for age, race, sex, and other factors. When further adjustments were made, for weight and other issues, the risk fell by 30%.


Continue Reading

“Our study provides unique evidence that sodium reduction might prevent cardiovascular disease and should dispel any residual concern that sodium reduction might be harmful,” the researchers concluded (BMJ. 2007: 334:885-895).

Americans get most of their sodium not from the saltshaker but from processed food. Those on a low-sodium diet should avoid ham, hot dogs, lunch meat, sausage, bacon, smoked fish, olives, pickles, canned soups, bouillon, broth, potato chips, and salted nuts.