HealthDay News — Atopic dermatitis in adulthood is associated with an increased risk for venous thromboembolism (VTE), according to a study published online in JAMA Dermatology.

Tai-Li Chen, MD, from Taipei Veterans General Hospital in Taiwan, and colleagues examined the risk for incident VTE among patients with atopic dermatitis. The analysis included 284,858 matched participants (142,429 participants with atopic dermatitis newly diagnosed between 2003 and 2017).

The researchers found that 0.7% of participants in the atopic dermatitis group and 0.6% in the nonatopic dermatitis cohort developed VTE, with incidence rates of 1.05 and 0.82 per 1,000 person-years, respectively. Compared with adults without atopic dermatitis, adults with atopic dermatitis had a significantly increased risk for incident VTE (hazard ratio, 1.28). Specifically, atopic dermatitis was associated with higher risks for deep vein thrombosis (hazard ratio, 1.26) and pulmonary embolism (hazard ratio, 1.30).

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“The results of this cohort study suggest that atopic dermatitis in adulthood is associated with an increased risk of VTE; however, the absolute risk difference of VTE between adults with and without atopic dermatitis appears small,” the authors wrote. “Nevertheless, cardiovascular examination and imperative management may be considered for adults with atopic dermatitis who present with symptoms suggestive of VTE. Future research is warranted to elucidate the pathophysiology underlying the association between atopic dermatitis and VTE.”

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