HealthDay News — One-fourth of patients receive unnecessary treatment with radioactive iodine after surgery for low-risk papillary thyroid cancer, according to a study published in the June issue of Surgical Oncology.
Ambria S. Moten, MD, from Temple University Hospital in Philadelphia, and colleagues used the Surveillance, Epidemiology and End Results database to identify papillary thyroid cancer patients. Low-risk patients were defined as T1 without metastasis.
The researchers found that of the 32,229 identified cases, 53.6% were low-risk. Low-risk patients were older (mean age, 51.3 vs 48.5 years) and more often female (81.6 vs 71.7%), white (69.7 vs 62%), and insured (87.6 vs 85.6%). Nearly one-fourth of low-risk patients received radioactive iodine (RAI) ablation. Overtreatment with RAI was predicted by age <45 years (odds ratio [OR], 1.393), age 45 to 64 years (OR, 1.275), male sex (OR, 1.191), Hispanic (OR, 1.236) and Asian race (OR, 1.306), and extensive lymphadenectomy (OR, 1.243).
“Identification of groups at risk for overtreatment can help impact practice patterns and improve the effective utilization of healthcare resources,” the authors write.