WASHINGTON — A single dose of an investigational influenza drug was able to reduce the duration of fever and viral shedding, researchers said here.

In a combined analysis of two randomized placebo-controlled trials, the neuraminidase inhibitor peramivir (Rapivab), given by injection within 48 hours of symptom onset, also lowered the amount of virus in the blood, according to Rich Whitley, MD, of the University of Alabama at Birmingham.

But while the drug reduced the time to resolution of symptoms — the primary endpoint of the trials — the difference from placebo was not statistically significant 

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