Model Estimates Herd Immunity Threshold for COVID-19
A mathematical model shows that SARS-CoV-2 disease-induced herd immunity level may be lower than the classical model assuming homogenous immunization.
Allergy and Immunology Information Center
Reactogenicity of Enhanced Influenza Vaccines in Older Adults
A team of investigators report on the findings from a randomized controlled trial of 3 enhanced influenza vaccines and a standard-dose vaccine in older adults.
First Large Clinical Trial of COVID-19 Vaccine Could Begin in July
A large clinical trial of the first US COVID-19 vaccine could begin next month, according to Moderna Inc., which developed the vaccine with the US National Institutes of Health.
Immunologic Status of Infants Born to COVID-19-Positive Mothers Found Normal
Researchers sought to analyze the immune status of newborns from mothers with COVID-19 in the third trimester.
HPV Vaccine Toolkit Increases Vaccination Rates in Primary Care
The purpose of this project is to implement and evaluate the effectiveness of the 4 Pillars Practice Transformation Program to increase uptake of the HPV vaccine among pediatric patients.
School-Based Health Centers Help Minimize Pediatric Under-Immunization
School-based health centers minimized the number of students excluded from school from under-immunization.
Adenovirus Type-5 Vectored COVID-19 Vaccine Shows Promise
A recombinant adenovirus type-5 (Ad5) vectored COVID-19 vaccine is safe, tolerable, and immunogenic.
Environmental Fungal Sensitization Associated With Worse Outcomes in COPD
Sensitization to environmental fungi was associated with poorer outcomes in patients with COPD.
Moderna’s COVID-19 Vaccine Gets Fast Track Designation
The FDA has granted Fast Track designation to the vaccine candidate, mRNA-1273 (Moderna), against the novel coronavirus (SARS-CoV-2).
AAP: Declines in Immunization During COVID-19 Pandemic Concerning
The AAP has issued a statement regarding recent data published by the Centers for Disease Control and Prevention (CDC) about a decline in pediatric vaccination during the COVID-19 pandemic.
Guidelines Issued for Managing Eosinophilic Esophagitis
Recommendations are presented for the management of eosinophilic esophagitis.
Influenza Vaccine Not Linked to Decrease in Hospitalizations or Mortality Among Elderly
Targeting the elderly (individuals aged 65 years) for influenza vaccination may not decrease hospitalization or mortality rates in this population.
FDA Approves Quadrivalent Meningococcal Vaccine MenQuadfi
The FDA has approved MenQuadfiTM Meningococcal (Groups A, C, Y, W; Sanofi Pasteur) Conjugate Vaccine for the prevention of invasive meningococcal disease caused by Neisseria meningitidis serogroups A, C, W, and Y in patients aged ≥2 years.
Celiac Disease Associated With Slight Increase in Mortality
Researchers sought to evaluate the association between celiac disease and mortality risk in a population-based cohort in Sweden.
PARS vs Asthma Predictive Index for Predicting Allergic, Nonallergic Asthma
The Pediatric Asthma Risk Score (PARS) may be able to predict the development of allergic and nonallergic asthma in children better than the Asthma Predictive Index.
Universal FLU-v Influenza Vaccine, Immunogenic and Warrants Further Testing
The adjuvanted, broad-spectrum influenza vaccine FLU-v was found to be immunogenic and merits phase 3 development to explore efficacy.
Test Vaccine Elicits Strong Ab Response to SARS-CoV-2 in Mice
Microneedle array delivery of trimeric coronavirus spike protein subunit vaccines seems promising for immunization against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
Rotavirus Vaccination Reduces Children Hospitalizations and Deaths
With increasing numbers of countries implementing the use of the rotavirus vaccine, rotavirus and acute gastroenteritis hospitalizations and mortalities continue to show a sustained reduction.
Pipeline: Investigational Therapies for COVID-19
Currently, there are no antivirals licensed by the FDA to treat patients with COVID-19.
Addressing Parents’ Concerns Improves Influenza Immunization Rates
Implementation of an influenza immunization program increased vaccinations rates from 44% to 57% the following year.
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