(HealthDay News) — If all clinicians followed US Preventive Services Task Force (USPSTF) guidelines for prescription of a statin, 9 million fewer adults would be taking such medication vs adherence to the American College of Cardiology/American Heart Association recommendations, according to a study published in the Journal of the American Medical Association.

Neha Pagidipati, MD, MPH, from the Duke Clinical Research Institute in Durham, NC, and colleagues evaluated data on 3,416 Americans in a nationally representative government health study.

The team found that if all doctors followed the latest guidelines from the USPSTF for statin use, the number of Americans aged 40 to 75 on these medications would rise by 16%. If all doctors followed the advice of the American College of Cardiology/American Heart Association, statin use would increase by 24%. The researchers estimated that if all US doctors followed the Task Force guidelines instead of the heart groups’ recommendations, about 9 million fewer Americans would be on a statin.

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“At the end of the day,” Pagidipati told HealthDay, “providers and patients need to have an open, informed discussion of the pros and cons of using a statin.”


  1. Pagidipati NJ, Navar AM, Mulder H, et al. Comparison of recommended eligibility for primary prevention statin therapy based on the US Preventive Services Task Force Recommendations vs the ACC/AHA guidelines. JAMA. 2017;317(5):1563-1567. doi:10.1001/jama.2017.3416