HealthDay News — Work stress and impaired sleep are associated with an increased risk for cardiovascular disease (CVD) mortality among workers with hypertension, according to a study published online April 27 in the European Journal of Preventive Cardiology.

Jian Li, MD, PhD, from the University of Düsseldorf in Germany, and colleagues conducted a prospective cohort study involving 1,959 workers with hypertension who were free from any CVD and diabetes. Participants were interviewed at baseline for work stress and impaired sleep; the correlations with CVD were examined.

The researchers identified 134 fatal CVD and 73 coronary heart disease (CHD) events during a mean follow-up of 17.8 years covering 34,900 person-years. Increased risk for CVD was seen for participants with work stress (hazard ratio, 1.56; 95% confidence interval, 0.81 to 2.98) or impaired sleep (hazard ratio, 1.76; 95% confidence interval, 0.96 to 3.22) compared with participants with low work stress and nonimpaired sleep; the highest risk for CVD mortality was seen for participants with both work stress and impaired sleep (hazard ratio, 2.94; 95% confidence interval, 1.18 to 7.33). The absolute CVD mortality risk was 7.13 cases per 1000 person-years for participants with both risk conditions compared with 3.05 cases per 1000 person-years in the reference group. The risk patterns were similar for CHD mortality.

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“Future interventions in the workplace to promote cardiovascular health, that is, stress management and sleep treatment, should be considered, especially among workers with chronic conditions, such as hypertension,” the authors write.

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