Although inpatient mortality and average length of stay have decreased for patients hospitalized for chronic obstructive pulmonary disease (COPD), the cost of hospitalization has significantly increased, according to a study published in COPD: Journal of Chronic Obstructive Pulmonary Disease.

The study, led by Chetna Jinjuvadia, MD, from the department of medicine at Wayne State University in Detroit, included patients aged 18 years and older from the National Inpatient Sample (NIS) databases from 2002 to 2010. The researchers used International Classification of Diseases-Ninth Revision (ICD-9) codes to determine patients who were hospitalized with a primary diagnosis of COPD and those who were admitted for other cases but had an underlying acute exacerbation of COPD. Hospital outcomes and length of stay were determined.

In 2002, COPD-related hospitalizations accounted for 3.31% of all hospitalizations. This number did not significantly change in 2010 (3.43%). From 2002 to 2010, there was a significant decrease in inpatient mortality, declining from 4.8% to 3.9%. There was also a significant decrease in average length of stay, decreasing from 6.4 days in 2002 to 6.0 days in 2010.

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Despite the reductions in mortality and length of stay, the researchers found a significant increase in hospitalization cost. In 2002, the average cost was $22,187, increasing to $38,455 in 2010.


  1. Jinjuvadia C, Jinjuvadia R, Mandapakala C, et al. Trends in outcomes, financial burden, and mortality for acute exacerbation of chronic obstructive pulmonary disease (COPD) in the United States from 2002 to 2010. COPD. Published July 15, 2016; doi:10.1080/15412555.2016.1199669 [Epub ahead of print]